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Health Services and Outcomes Research Methodology OnlineFirst articles

16-05-2024

Entropy balancing versus vector-based kernel weighting for causal inference in categorical treatment settings

Applied health services researchers often use methods that address observed confounding in attempts to estimate causal treatment effects. In prior work, vector-based kernel weighting (VBKW) was shown to minimize bias and maximize efficiency …

Authors:
Yevgeniy Feyman, Jessica Lum, Daniel Asfaw, Steven Pizer, Melissa Garrido

18-04-2024

A terminal trend model for longitudinal medical cost data and survival

A joint modeling approach on survival and longitudinal data has proven to be valuable in end of life applications, especially when there is a strong relationship between the longitudinal measurements and survival outcomes in the presence of high …

Authors:
Qian Yang, Tor D. Tosteson, Anna N. A. Tosteson, Jeffrey C. Munson

16-04-2024 | Mood Disorders

Multimodal mental state analysis

Self-reports or professional interviews have typically been used to diagnose depression, although these methods often miss significant behavioral signals. Sometimes, people with depression may not express their feelings accurately, which can make …

Authors:
Bipin Kumar Rai, Ishika Jain, Baibhav Tiwari, Abhay Saxena

Open Access 12-04-2024

Practical challenges in mediation analysis: a guide for applied researchers

Mediation analysis is a statistical approach that can provide insights regarding the intermediary processes by which an intervention or exposure affects a given outcome. Mediation analyses rose to prominence, particularly in social science …

Authors:
Megan S. Schuler, Donna L. Coffman, Elizabeth A. Stuart, Trang Q. Nguyen, Brian Vegetabile, Daniel F. McCaffrey

Open Access 18-03-2024 | COVID-19 | Case Study

A machine learning approach for diagnostic and prognostic predictions, key risk factors and interactions

Machine learning (ML) has the potential to revolutionize healthcare, allowing healthcare providers to improve patient-care planning, resource planning and utilization. Furthermore, identifying key-risk-factors and interaction-effects can help …

Authors:
Murtaza Nasir, Nichalin S. Summerfield, Stephanie Carreiro, Dan Berlowitz, Asil Oztekin

15-02-2024 | Research

Evaluating medical providers in terms of patient health disparities: a statistical framework

Statistical methods for provider profiling are designed to measure healthcare quality and create incentives for low-quality providers to improve. While most existing healthcare quality metrics assess the overall treatment delivered to providers’ …

Authors:
Nicholas Hartman, Claudia Dahlerus

Open Access 02-02-2024 | Research

Exact-matching algorithms using administrative health claims database equivalence factors for real-world data analysis based on the target trial emulation framework

Real-world data have become increasingly important in medical science and healthcare. A new, effective, and practically feasible statistical design is needed to unlock the potential of real-world data that decision-makers and practitioners can use …

Authors:
Yuichi Nishioka, Emiri Morita, Saki Takeshita, Sakura Tamamoto, Tomoya Myojin, Tatsuya Noda, Tomoaki Imamura

24-01-2024

Blockchain based E-procurement system in healthcare

Public procurement, a critical facet in acquiring goods and services, has garnered scholarly attention in e-procurement. However, its application in healthcare remains underexplored. This paper addresses this gap by proposing a decentralized …

Authors:
Bipin Kumar Rai, Vedant Dubey, Khushi Dubey

Open Access 29-11-2023

ATRAcTR (Authentic Transparent Relevant Accurate Track-Record): a screening tool to assess the potential for real-world data sources to support creation of credible real-world evidence for regulatory decision-making

Adoption and use of real-world data (RWD) for decision-making has been complicated by concerns regarding whether RWD was fit-for-purpose or was of sufficient validity to support the creation of credible RWE. This has greater urgency as regulatory …

Authors:
Marc L. Berger, William H. Crown, Jim Z. Li, Kelly H. Zou

28-11-2023

Evaluation of survey delivery methods in a national study of Veteran’s healthcare preferences

Researchers often use survey methods to elicit patient perspectives on their healthcare. Survey results are often subject to response bias and missing data. As part of an observational study of Veterans’ healthcare preferences, we conducted a …

Authors:
Natalie Disher, Jennifer Scott, Anna Tyzik, Sara Golden, Georgia Baker, Denise M. Hynes, Christopher G. Slatore

18-11-2023

Propensity score weighting with survey weighted data when outcomes are binary: a simulation study

Propensity score methods have been widely adopted in observational studies, however research on propensity score-based weighting (PSW) methods in complex survey data settings is lacking, particularly for binary outcomes. We conducted a simulation …

Authors:
Chen Yang, Meaghan S. Cuerden, Wei Zhang, Melissa Aldridge, Lihua Li

13-11-2023

Bootstrap approach to disparity testing with source uncertainty in the data

This article addresses the problem of one-sided hypothesis testing on the means of two populations when there is uncertainty as to which population a datum is drawn. Such situations arise, for example, in the use of Bayesian imputation methods to …

Authors:
Gary C. McDonald, Joseph F. Willard

01-11-2023 | Parkinson's Disease

Descriptive and inferential analysis of features for Dysphonia and Dysarthria Parkinson’s disease symptoms

Parkinson’s disease is related to nervous system disorders in human beings. In this paper, the status of Parkinson’s disease has been predicted based on the analysis of features of two Parkinson’s disease symptoms: Dysphonia and Dysarthria. The …

Authors:
Saiyed Umer, Ranjeet Kumar Rout

Open Access 24-10-2023 | Care

Inspecting the quality of care: a comparison of CUSUM methods for inter hospital performance

During the past 14 years, a clinical audit has been used in the Netherlands to provide hospitals with data on their performance in colorectal cancer care. Continuous feedback on the quality of care provided at each hospital is essential to improve …

Authors:
Daniel Gomon, Julie Sijmons, Hein Putter, Jan Willem Dekker, Rob Tollenaar, Michel Wouters, Pieter Tanis, Marta Fiocco, Mirko Signorelli

Open Access 15-09-2023 | Pathology

Emergency department pathology order support tool (ED POST): a protocol using qualitative inquiry to inform design and development of a prototype to reduce low value care

Laboratory tests have an important role in informing diagnosis and aiding in the determination of appropriate courses of management and/or treatment in the Emergency Department setting. Over-ordering of laboratory tests can lead to increased costs …

Authors:
Judith Thomas, Julie Li, Craig Scowen, Alex Eigenstetter, Andrew Georgiou

04-09-2023

Usability evaluation of interoperability interfaces in electronic medical record systems

Interoperability plays a crucial role in facilitating seamless data sharing across system boundaries, necessitating collaborative efforts among multiple systems. To achieve this, the presence of a common reference model for data exchange and …

Authors:
Nadeem Q. Mehmood, Syed Z. Mahfooz, Saeed Faroom, Steffen Mencke, Nafees Qamar