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Published in: Acta Neurochirurgica 2/2009

01-02-2009 | Brief Report of a Special Case

Isolated Whipple disease of the brain resembling a tumour

Authors: James L. Frazier, Alfredo Quinones-Hinojosa

Published in: Acta Neurochirurgica | Issue 2/2009

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Abstract

Introduction

Isolated Whipple disease of the central nervous system is a rare occurrence. Migratory arthralgias and gastrointestinal problems, including malabsorption, abdominal pain, diarrhea, and weight loss, are common presenting symptoms.

Discussion

For those patients with systemic signs and symptoms of Whipple disease, 6% to 43% will have clinically manifested CNS involvement that may include alterations in personality, ataxia, and dementia. We report our experience with a patient, who was successfully treated for Whipple disease 12 years prior to presentation and had a magnetic resonance image of the brain that revealed two solitary lesions resembling a tumor upon presentation.
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Metadata
Title
Isolated Whipple disease of the brain resembling a tumour
Authors
James L. Frazier
Alfredo Quinones-Hinojosa
Publication date
01-02-2009
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 2/2009
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-008-0180-6

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