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BMC Neurology
Published in: BMC Neurology 1/2008

Open Access 01-12-2008 | Research article

Ischemic stroke incidence in Santa Coloma de Gramenet (ISISCOG), Spain. A community-based study

Authors: María Teresa Alzamora, Marta Sorribes, Antonio Heras, Nicolás Vila, Marisa Vicheto, Rosa Forés, José Sánchez-Ojanguren, Amparo Sancho, Guillem Pera, the "ISISCOG Study Group"

Published in: BMC Neurology | Issue 1/2008

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Abstract

Background

In Spain, stroke is one of the major causes of death and the main cause of severe disability in people over 65 years. We analyzed the incidence of ischemic stroke, stroke subtypes, case fatality and disability at 90 days after the event in a Spanish population.

Methods

A prospective community-based register of ischemic strokes was established in Santa Coloma de Gramenet (Barcelona) [116,220 inhabitants of all ages, according to the municipal census of December 31,2001], from January 1 to December 31, 2003.
Standard definitions and case finding methods were used to identify all cases in all age groups. Every patient underwent a complete clinical evaluation and systematic tests including neuroimaging (CT/MRI) and vascular studies (carotid duplex ultrasound intra and extracranial and MR angiography).

Results

Over a one year period, 196 ischemic strokes were registered [107 men; median age = 76 years (range 39–98)], being the first event in 159 patients (81.1%) and a recurrent stroke in 37 (18.9%). After age-adjustment to the European population, the incidence of ischemic stroke per 100,000 inhabitants was 172 (95% CI, 148–196); 219 (176–261) in men and 133 (105–160) in women, with an annual incidence for first ischemic stroke of 139 (118–161); 165 (128–201) in men and 115 (89–140) in women. The incidence of stroke increased with age.
Stroke subtypes (TOAST classification criteria) were lacunar in 28.8%, atherothrombotic in 18.6%, cardioembolic in 26.6% and undetermined in 26.0% of patients. At 90 days, the case-fatality was 12%, and among survivors, moderate-to-severe disability was present in 45 % at 3 months.

Conclusion

This prospective community-based study shows one of the lowest incidences of stroke in Europe, as well as one of the lowest case fatality and disability rates at 90 days after stroke.
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Metadata
Title
Ischemic stroke incidence in Santa Coloma de Gramenet (ISISCOG), Spain. A community-based study
Authors
María Teresa Alzamora
Marta Sorribes
Antonio Heras
Nicolás Vila
Marisa Vicheto
Rosa Forés
José Sánchez-Ojanguren
Amparo Sancho
Guillem Pera
the "ISISCOG Study Group"
Publication date
01-12-2008
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2008
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/1471-2377-8-5

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