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Published in: BMC Anesthesiology 1/2015

Open Access 01-12-2015 | Research article

Is tracheostomy a better choice than translaryngeal intubation for critically ill patients requiring mechanical ventilation for more than 14 days? A comparison of short-term outcomes

Authors: Wei-Chieh Lin, Chang-Wen Chen, Jung-Der Wang, Liang-Miin Tsai

Published in: BMC Anesthesiology | Issue 1/2015

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Abstract

Background

Tracheostomy is recommended for patients receiving mechanical ventilation (MV) for 14 days or more in the intensive care unit (ICU). Nevertheless, many patients undergoing prolonged MV remain intubated via the translaryngeal route. The aim of this study was to examine the influence of tracheostomy and persistent translaryngeal intubation on short-term outcomes in patients mechanically ventilated for ≥14 days.

Methods

A retrospective study was conducted using the admissions database of a 75-bed ICU from January 1, 2012, to December 31, 2012. Patients who required prolonged MV without tracheostomy at the time of initiation of a ventilator were included. The outcomes were successful weaning, and ICU and in-hospital death. Cox models were constructed to calculate the influence of tracheostomy on the outcome measures while adjusting for other potentially confounding factors.

Results

Of the 508 patients requiring prolonged MV, 164 were tracheostomized after a median 18 days of MV. Patients in whom translaryngeal intubation was maintained had significantly higher ICU (42.7 % versus 17.1 %, p <0.001) and in-hospital (54.1 % versus 22.0 %, p <0.001) mortality rates, and a significantly lower successful weaning rate (40.4 % versus 68.9 %, p <0.001). The results were consistent after matching for the propensity score of performing tracheostomy. Furthermore, a time-dependent covariate Cox model showed that a tracheostomy was independently associated with lower in-hospital mortality (adjusted hazard ratio [aHR], 0.26; 95 % confidence interval [CI], 0.18–0.39) and higher successful weaning rate (aHR, 2.05; 95 % CI, 1.56–2.68).

Conclusions

Tracheostomy is associated with lower in-hospital mortality and higher successful weaning rates in ICU patients receiving prolonged MV. However, the cost-effectiveness and long-term outcomes of tracheostomy for this cohort require further study.
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Metadata
Title
Is tracheostomy a better choice than translaryngeal intubation for critically ill patients requiring mechanical ventilation for more than 14 days? A comparison of short-term outcomes
Authors
Wei-Chieh Lin
Chang-Wen Chen
Jung-Der Wang
Liang-Miin Tsai
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2015
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-015-0159-9

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