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01-04-2017 | Review

Is there enough evidence to use botulinum toxin injections for bruxism management? A systematic literature review

Authors: Giancarlo De la Torre Canales, Mariana Barbosa Câmara-Souza, Camilla Fraga do Amaral, Renata Cunha Matheus Rodrigues Garcia, Daniele Manfredini

Published in: Clinical Oral Investigations | Issue 3/2017

Abstract

Objective

The objective of the study was to conduct a systematic review of the literature assessing the effects of botulinum toxin (BoNT-A) injections in the management of bruxism.

Materials and methods

Search for articles involved the PubMed, Scopus, Web of Science, Embase, Cochrane, Scielo and Lilacs databases. Specific terms were used and the search carried out from 1980 to March 2016 by three independent researchers. Randomized controlled studies (RCTs), prospective and before–after studies that applied BoNT-A at the masseter and/or temporalis muscles were included.

Results

Three RCTs and two uncontrolled before–after studies out of 904 identified citations were included in this review. All five articles dealt with sleep bruxism and featured a small sample size. None of them was about awake bruxism. Two randomized clinical trials were double-blinded, with a control group using saline solution. Two studies used polysomnography/electromyography for sleep bruxism diagnosis, whilst others were based on history taking and clinical examination. All studies using subjective evaluations for pain and jaw stiffness showed positive results for the BoNT-A treatment. In contrast, the two studies using objective evaluations did not demonstrate any reduction in bruxism episodes, but a decrease in the intensity of muscles contractions.

Conclusion

Despite the paucity of works on the topic, BoNT-A seems to be a possible management option for sleep bruxism, minimizing symptoms and reducing the intensity of muscle contractions, although further studies are necessary especially as far as the treatment indications for bruxism itself is concerned.

Clinical relevance

BoNT-A has been increasingly diffused in dentistry over recent years, being also used for pain management in patients with bruxism. Nonetheless, there is no consensus about its effects in this disorder.

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Title: Is there enough evidence to use botulinum toxin injections for bruxism management? A systematic literature review
Authors: Giancarlo De la Torre Canales
Mariana Barbosa Câmara-Souza
Camilla Fraga do Amaral
Renata Cunha Matheus Rodrigues Garcia
Daniele Manfredini
Publication date: 01-04-2017
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 3/2017
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-017-2092-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Is there enough evidence to use botulinum toxin injections for bruxism management? A systematic literature review

Abstract

Objective

Materials and methods

Results

Conclusion

Clinical relevance

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusion

Clinical relevance

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