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01-05-2007 | Original Article

Is single-dose fosfomycin trometamol a good alternative for asymptomatic bacteriuria in the second trimesterof pregnancy?

Authors: Ömer Bayrak, Ersin Çimentepe, İlknur İnegöl, Ali Fuat Atmaca, Candan İltemir Duvan, Akif Koç, Nilgün Öztürk Turhan

Published in: International Urogynecology Journal | Issue 5/2007

Abstract

Untreated asymptomatic bacteriuria has been associated with acute pyelonephritis, which may have a role in many maternal and fetal complications. Acute pyelonephritis in pregnancy is related to anemia, septicemia, transient renal dysfunction, and pulmonary insufficiency. A randomized study was conducted to assess the clinical and microbiological efficacy of a single dose of fosfomycin trometamol for the treatment of asymptomatic bacteriuria in the second trimester of pregnancy compared with a 5-day regimen of cefuroxime axetyl. Forty-four women received fosfomycin trometamol and 40 women received cefuroxime axetyl. There were no statistically significant differences between both groups regarding the mean age and mean duration of pregnancy. Therapeutic success was achieved in 93.2% of the patients treated with fosfomycin trometamol vs 95% of those treated with cefuroxime axetyl. A single dose of fosfomycin trometamol is a safe and effective alternative in the treatment of asymptomatic urinary tract infections in the second trimester of pregnancy.

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Title: Is single-dose fosfomycin trometamol a good alternative for asymptomatic bacteriuria in the second trimesterof pregnancy?
Authors: Ömer Bayrak
Ersin Çimentepe
İlknur İnegöl
Ali Fuat Atmaca
Candan İltemir Duvan
Akif Koç
Nilgün Öztürk Turhan
Publication date: 01-05-2007
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 5/2007
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-006-0190-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Is single-dose fosfomycin trometamol a good alternative for asymptomatic bacteriuria in the second trimesterof pregnancy?

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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