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01-09-2003 | Editorial

Is prostacyclin an inodilator?

Author: Sven-Erik Ricksten

Published in: Intensive Care Medicine | Issue 9/2003

Excerpt

Prostacyclin is a naturally occurring substance that in addition to an inhibitory effect of platelet aggregation is a potent vasodilator with a half-life of 2–3 min [1, 2]. Prostacyclin activates the intracellular enzyme adenylyl cyclase, through specific membrane receptors, and increases intracellular cyclic adenosine monophosphate (cAMP), which in turn decreases free intracellular calcium concentration of vascular smooth muscle cells [2]. …

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Title: Is prostacyclin an inodilator?
Author: Sven-Erik Ricksten
Publication date: 01-09-2003
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 9/2003
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-003-1834-8

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Is prostacyclin an inodilator?

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