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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 3/2004

01-09-2004 | Oral presentation

Is leptin the link between obesity and osteoarthritis?

Authors: P Pottie, N Presle, H Dumond, B Terlain, D Mainard, D Leuille, P Netter

Published in: Arthritis Research & Therapy | Special Issue 3/2004

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Excerpt

Leptin is a small, 16-kDa protein produced and secreted primarily by adipocytes found in white adipose tissue. Initially discovered as a central regulator of appetite and energy expenditure, leptin may also be involved in the regulation of metabolic activity in the growth plate and bone. Since obese individuals have an increased incidence of osteoarthritis (OA), we evaluated the contribution of leptin to cartilage changes associated with this degenerative disease. …
Metadata
Title
Is leptin the link between obesity and osteoarthritis?
Authors
P Pottie
N Presle
H Dumond
B Terlain
D Mainard
D Leuille
P Netter
Publication date
01-09-2004
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 3/2004
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar1342

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