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Critical Care
Published in: Critical Care 4/2005

01-08-2005 | Commentary

Is it time to increase the frequency of use of high-frequency oscillatory ventilation?

Authors: Jeffrey M Singh, Niall D Ferguson

Published in: Critical Care | Issue 4/2005

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Abstract

In this issue of Critical Care, Bollen and colleagues present the results of a multicentre randomised controlled trial, comparing high-frequency oscillatory ventilation with conventional ventilation as the primary ventilation mode for adults with acute respiratory distress syndrome. The study was stopped early after recruiting only 61 patients because of declining enrolment, and although no differences were detected in any primary or secondary endpoint, this trial only had sufficient power to detect extreme differences in outcomes between groups. This editorial attempts to put these results in context with previous work and highlights challenges to be addressed in future studies.
Literature
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Ferguson ND, Chiche JD, Kacmarek RM, Hallett DC, Mehta S, Findlay GP, Granton JT, Slutsky AS, Stewart TE: Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome: the Treatment with Oscillation and an Open Lung Strategy (TOOLS) Trial pilot study. Crit Care Med 2005, 33: 479-486. 10.1097/01.CCM.0000155785.23200.9ECrossRefPubMed
Metadata
Title
Is it time to increase the frequency of use of high-frequency oscillatory ventilation?
Authors
Jeffrey M Singh
Niall D Ferguson
Publication date
01-08-2005
Publisher
BioMed Central
Published in
Critical Care / Issue 4/2005
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc3761

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