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Published in: International Orthopaedics 5/2013

01-05-2013 | Original Paper

Is hybrid imaging (SPECT/CT) a useful adjunct in the management of suspected facet joints arthropathy?

Authors: Hosam E. Matar, Shaunak Navalkissoor, Marko Berovic, Rohit Shetty, Nicholas Garlick, Adrian T. H. Casey, Ann-Marie Quigley

Published in: International Orthopaedics | Issue 5/2013

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Abstract

Purpose

The purpose of this study was to assess the value of SPECT/CT imaging in patients with chronic spinal pain.

Methods

This was a retrospective consecutive study. Patients with chronic neck or back pain from outpatient spinal clinics with clinical features raising the possibility of a facetogenic pain generator and non-conclusive MRI/CT findings were included. Imaging was performed on a dual-headed, hybrid SPECT/CT γ-camera with a low-dose CT transmission scan acquired after the SPECT study. SPECT/CT studies were viewed in the coronal, axial, and sagittal planes and in 3-dimensional mode. Descriptive statistical analysis was performed.

Results

Seventy-two patients were included (37 females, 35 males, mean age of 53.9 years). There were 25 cervical spine scans and 49 lumbar spine scans. In the cervical spine group, 13 (52 %) patients had scintigraphically active cervical facet joint arthropathy and ten (36 %) had other pathology identified. Two thirds of patients diagnosed with facet joint arthropathy received steroid guided injections following their scans. In the lumbar spine group 34 (69.4 %) patients had scintigraphically active lumbar facet joint arthropathy and eight had other pathology identified. Twenty patients (58.8 %) diagnosed with facet joint arthropathy subsequently received steroid guided injections.

Conclusions

Hybrid SPECT/CT imaging identified potential pain generators in 92 % of cervical spine scans and 86 % of lumbar spine scans. The scan precisely localised SPECT positive facet joint targets in 65 % of the referral population and a clinical decision to inject was made in 60 % of these cases.
Literature
1.
go back to reference Bogduk N (2005) The zygapophysial joints. In Clinical Anatomy of the Lumbar Spine and Sacrum. 3rd edn. Churchill Living stone, New York Bogduk N (2005) The zygapophysial joints. In Clinical Anatomy of the Lumbar Spine and Sacrum. 3rd edn. Churchill Living stone, New York
2.
go back to reference Manchikanti L, Boswell MV, Singh V, Pampati V, Damron KS, Beyer CD (2004) Prevalence of facet joint pain in chronic spinal pain of cervical, thoracic, and lumbar regions. BMC Musculoskelet Disord 5:15PubMedCrossRef Manchikanti L, Boswell MV, Singh V, Pampati V, Damron KS, Beyer CD (2004) Prevalence of facet joint pain in chronic spinal pain of cervical, thoracic, and lumbar regions. BMC Musculoskelet Disord 5:15PubMedCrossRef
3.
go back to reference Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N (1994) Clinical features of patients with pain stemming from the lumbar zygapophysial joints. Is the lumbar facet syndrome a clinical entity? Spine 19:1132–1137PubMedCrossRef Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N (1994) Clinical features of patients with pain stemming from the lumbar zygapophysial joints. Is the lumbar facet syndrome a clinical entity? Spine 19:1132–1137PubMedCrossRef
4.
go back to reference Fukui S, Ohseto K, Shiotani M, Ohno K, Karasawa H, Naganuma Y (1997) Distribution of referral pain from the lumbar zyg apophyseal joints and dorsal rami. Clin J Pain 13:303–307PubMedCrossRef Fukui S, Ohseto K, Shiotani M, Ohno K, Karasawa H, Naganuma Y (1997) Distribution of referral pain from the lumbar zyg apophyseal joints and dorsal rami. Clin J Pain 13:303–307PubMedCrossRef
5.
go back to reference Windsor RE, King FJ, Roman SJ, Tata N, Cone-Sullivan LA, Thampi S, Acebey M, Gilhool JJ, Rao R, Sugar R (2002) Electrical stimulation induced lumbar medial branch referral patterns. Pain Physician 5:347–353PubMed Windsor RE, King FJ, Roman SJ, Tata N, Cone-Sullivan LA, Thampi S, Acebey M, Gilhool JJ, Rao R, Sugar R (2002) Electrical stimulation induced lumbar medial branch referral patterns. Pain Physician 5:347–353PubMed
6.
go back to reference Boswell MV, Shah RV, Everett CR, Sehgal N, Mckenzie-Brown AM, Abdi S, Bowman RC, Deer TR, Datta S, Colson JD, Spillane WF, Smith HS, Lucas-Levin LF, Burton AW, Chopra P, Staats PS, Wasserman RA, Manchikanti L (2005) Interventional techniques in the management of chronic spinal pain: Evidence-based practice guidelines. Pain Physician 8:1–47PubMed Boswell MV, Shah RV, Everett CR, Sehgal N, Mckenzie-Brown AM, Abdi S, Bowman RC, Deer TR, Datta S, Colson JD, Spillane WF, Smith HS, Lucas-Levin LF, Burton AW, Chopra P, Staats PS, Wasserman RA, Manchikanti L (2005) Interventional techniques in the management of chronic spinal pain: Evidence-based practice guidelines. Pain Physician 8:1–47PubMed
7.
go back to reference Bogduk N (2008) Evidence-informed management of chronic low back pain with facet injections and radiofrequency neurotomy. Spine J 8:56–64PubMedCrossRef Bogduk N (2008) Evidence-informed management of chronic low back pain with facet injections and radiofrequency neurotomy. Spine J 8:56–64PubMedCrossRef
8.
go back to reference Sehgal N, Dunbar EE, Shah RV, Colson JD (2007) Systematic review of diagnostic utility of facet (zygapophysial) joint injections in chronic spinal pain: an update. Pain Physician 10:213–228PubMed Sehgal N, Dunbar EE, Shah RV, Colson JD (2007) Systematic review of diagnostic utility of facet (zygapophysial) joint injections in chronic spinal pain: an update. Pain Physician 10:213–228PubMed
9.
go back to reference Delbeke D, Schöder H, Martin WH, Wahl RL (2009) Hybrid imaging (SPECT/CT and PET/CT): improving therapeutic decisions. Semin Nucl Med 39:308–340PubMedCrossRef Delbeke D, Schöder H, Martin WH, Wahl RL (2009) Hybrid imaging (SPECT/CT and PET/CT): improving therapeutic decisions. Semin Nucl Med 39:308–340PubMedCrossRef
10.
go back to reference Filippi L, Schillaci O (2006) Usefulness of hybrid SPECT/CT in 99mTc-HMPAO-labeled leukocyte scintigraphy for bone and joint infections. J Nucl Med 47:1908–1913PubMed Filippi L, Schillaci O (2006) Usefulness of hybrid SPECT/CT in 99mTc-HMPAO-labeled leukocyte scintigraphy for bone and joint infections. J Nucl Med 47:1908–1913PubMed
11.
go back to reference Utsunomiya D, Shiraishi S, Imuta M, Tomiguchi S, Kawanaka K, Morishita S, Awai K, Yamashita Y (2006) Added value of SPECT/CT fusion in assessing suspected bone metastasis: comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology 238:264–271PubMedCrossRef Utsunomiya D, Shiraishi S, Imuta M, Tomiguchi S, Kawanaka K, Morishita S, Awai K, Yamashita Y (2006) Added value of SPECT/CT fusion in assessing suspected bone metastasis: comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology 238:264–271PubMedCrossRef
12.
go back to reference Dolan AL, Ryan PJ, Arden NK, Stratton R, Wedley JR, Hamann W, Fogelman I, Gibson T (1996) The value of SPECT scans in identifying back pain likely to benefit from facet joint injection. Br J Rheumatol 35:1269–1273PubMedCrossRef Dolan AL, Ryan PJ, Arden NK, Stratton R, Wedley JR, Hamann W, Fogelman I, Gibson T (1996) The value of SPECT scans in identifying back pain likely to benefit from facet joint injection. Br J Rheumatol 35:1269–1273PubMedCrossRef
13.
go back to reference Dutton JA, Hughes SP, Peters AM (2000) SPECT in the management of patients with back pain and spondylolysis. Clin Nucl Med 25:93–96PubMedCrossRef Dutton JA, Hughes SP, Peters AM (2000) SPECT in the management of patients with back pain and spondylolysis. Clin Nucl Med 25:93–96PubMedCrossRef
14.
go back to reference Holder LE, Machin JL, Asdourian PL, Links JM, Sexton CC (1995) Planar and high-resolution SPECT bone imaging in the diagnosis of facet syndrome. J Nucl Med 36:37–44PubMed Holder LE, Machin JL, Asdourian PL, Links JM, Sexton CC (1995) Planar and high-resolution SPECT bone imaging in the diagnosis of facet syndrome. J Nucl Med 36:37–44PubMed
15.
go back to reference Horger M, Bares R (2006) The role of single-photon emission computed tomography/computed tomography in benign and malignant bone disease. Semin Nucl Med 36:286–294PubMedCrossRef Horger M, Bares R (2006) The role of single-photon emission computed tomography/computed tomography in benign and malignant bone disease. Semin Nucl Med 36:286–294PubMedCrossRef
16.
go back to reference Husarik DB, Steinert HC (2007) Single-photon emission computed tomography/computed tomography for sentinel node mapping in breast cancer. Semin Nucl Med 37:29–33PubMedCrossRef Husarik DB, Steinert HC (2007) Single-photon emission computed tomography/computed tomography for sentinel node mapping in breast cancer. Semin Nucl Med 37:29–33PubMedCrossRef
17.
go back to reference Krausz Y, Israel O (2006) Single-photon emission computed tomography/computed tomography in endocrinology. Semin Nucl Med 36:267–274PubMedCrossRef Krausz Y, Israel O (2006) Single-photon emission computed tomography/computed tomography in endocrinology. Semin Nucl Med 36:267–274PubMedCrossRef
18.
go back to reference Hirschmann MT, Davda K, Iranpour F, Rasch H, Friederich NF (2011) Combined single photon emission computerised tomography and conventional computerised tomography (SPECT/CT) in patellofemoral disorders: a clinical review. Int Orthop 35:675–680PubMedCrossRef Hirschmann MT, Davda K, Iranpour F, Rasch H, Friederich NF (2011) Combined single photon emission computerised tomography and conventional computerised tomography (SPECT/CT) in patellofemoral disorders: a clinical review. Int Orthop 35:675–680PubMedCrossRef
19.
go back to reference Hirschmann MT, Mathis D, Rasch H, Amsler F, Friederich NF, Arnold MP (2012) SPECT/CT tracer uptake is influenced by tunnel orientation and position of the femoral and tibial ACL graft insertion site. Int Orthop. doi:10.1007/s00264-012-1704-5 [Epub ahead of print] Hirschmann MT, Mathis D, Rasch H, Amsler F, Friederich NF, Arnold MP (2012) SPECT/CT tracer uptake is influenced by tunnel orientation and position of the femoral and tibial ACL graft insertion site. Int Orthop. doi:10.​1007/​s00264-012-1704-5 [Epub ahead of print]
20.
go back to reference McDonald M, Cooper R, Wang MY (2007) Use of computed tomography-single-photon emission computed tomography fusion for diagnosing painful facet arthropathy. Technical note. Neurosurg Focus 22:E2PubMedCrossRef McDonald M, Cooper R, Wang MY (2007) Use of computed tomography-single-photon emission computed tomography fusion for diagnosing painful facet arthropathy. Technical note. Neurosurg Focus 22:E2PubMedCrossRef
21.
go back to reference Strobel K, Burger C, Seifert B (2007) Husarik DB, Soyka JD, Hany TF (2007) Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. AJR Am J Roentgenol 188:W467–W474PubMedCrossRef Strobel K, Burger C, Seifert B (2007) Husarik DB, Soyka JD, Hany TF (2007) Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. AJR Am J Roentgenol 188:W467–W474PubMedCrossRef
22.
go back to reference Strobel K, Burger C, Seifert B, Husarik DB, Soyka JD, Hany TF (2007) Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. AJR Am J Roentgenol 188:467–474CrossRef Strobel K, Burger C, Seifert B, Husarik DB, Soyka JD, Hany TF (2007) Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. AJR Am J Roentgenol 188:467–474CrossRef
23.
go back to reference Gorbach C, Schmid MR, Elfering A, Hodler J, Boos N (2006) Therapeutic efficacy of facet joint blocks. AJR Am J Roentgenol 186:1228–1233PubMedCrossRef Gorbach C, Schmid MR, Elfering A, Hodler J, Boos N (2006) Therapeutic efficacy of facet joint blocks. AJR Am J Roentgenol 186:1228–1233PubMedCrossRef
24.
go back to reference Savigny P, Kuntze S, Watson P, Underwood M, Ritchie G, Cotterell M, Hill D, Browne N, Buchanan E, Coffey P, Dixon P, Drummond C, Flanagan M, Greenough C, Griffiths M, Halliday-Bell J, Hettinga D, Vogel S, Walsh D (2009) Low back pain: early management of persistent non-specific low back pain. National Collaborating Centre for Primary Care and Royal College of General Practitioners, London Savigny P, Kuntze S, Watson P, Underwood M, Ritchie G, Cotterell M, Hill D, Browne N, Buchanan E, Coffey P, Dixon P, Drummond C, Flanagan M, Greenough C, Griffiths M, Halliday-Bell J, Hettinga D, Vogel S, Walsh D (2009) Low back pain: early management of persistent non-specific low back pain. National Collaborating Centre for Primary Care and Royal College of General Practitioners, London
25.
go back to reference Carrino JA, Lurie JD, Tosteson AN, Tosteson TD, Carragee EJ, Kaiser J, Grove MR, Blood E, Pearson LH, Weinstein JN, Herzog R (2009) Lumbar spine: reliability of MR imaging findings. Radiology 250:161–170PubMedCrossRef Carrino JA, Lurie JD, Tosteson AN, Tosteson TD, Carragee EJ, Kaiser J, Grove MR, Blood E, Pearson LH, Weinstein JN, Herzog R (2009) Lumbar spine: reliability of MR imaging findings. Radiology 250:161–170PubMedCrossRef
26.
go back to reference Even-Sapir E (2005) Imaging of malignant bone involvement by morphologic, scintigraphic, and hybrid modalities. J Nucl Med 46:1356–1367PubMed Even-Sapir E (2005) Imaging of malignant bone involvement by morphologic, scintigraphic, and hybrid modalities. J Nucl Med 46:1356–1367PubMed
27.
go back to reference Papathanassiou D, Bruna-Muraille C, Jouannaud C, Gagneux-Lemoussu L, Eschard JP, Liehn JC (2009) Single-photon emission computed tomography combined with computed tomography (SPECT/CT) in bone diseases. Joint Bone Spine 76:474–480PubMedCrossRef Papathanassiou D, Bruna-Muraille C, Jouannaud C, Gagneux-Lemoussu L, Eschard JP, Liehn JC (2009) Single-photon emission computed tomography combined with computed tomography (SPECT/CT) in bone diseases. Joint Bone Spine 76:474–480PubMedCrossRef
28.
go back to reference Horger M, Eschmann SM, Pfannenberg C, Vonthein R, Besenfelder H, Claussen CD, Bares R (2004) Evaluation of combined transmission and emission tomography for classification of skeletal lesions. AJR Am J Roentgenol 183:655–661PubMedCrossRef Horger M, Eschmann SM, Pfannenberg C, Vonthein R, Besenfelder H, Claussen CD, Bares R (2004) Evaluation of combined transmission and emission tomography for classification of skeletal lesions. AJR Am J Roentgenol 183:655–661PubMedCrossRef
29.
go back to reference Tharp K, Israel O, Hausmann J, Bettman L, Martin WH, Daitzchman M, Sandler MP, Delbeke D (2004) Impact of 131I-SPECT/CT images obtained with an integrated system in the follow-up of patients with thyroid carcinoma. Eur J Nucl Med Mol Imaging 31:1435–1442PubMedCrossRef Tharp K, Israel O, Hausmann J, Bettman L, Martin WH, Daitzchman M, Sandler MP, Delbeke D (2004) Impact of 131I-SPECT/CT images obtained with an integrated system in the follow-up of patients with thyroid carcinoma. Eur J Nucl Med Mol Imaging 31:1435–1442PubMedCrossRef
30.
go back to reference Even-Sapir E, Keidar Z, Sachs J, Engel A, Bettman L, Gaitini D, Guralnik L, Werbin N, Iosilevsky G, Israel O (2001) The new technology of combined transmission and emission tomography in evaluation of endocrine neoplasms. J Nucl Med 42:998–1004PubMed Even-Sapir E, Keidar Z, Sachs J, Engel A, Bettman L, Gaitini D, Guralnik L, Werbin N, Iosilevsky G, Israel O (2001) The new technology of combined transmission and emission tomography in evaluation of endocrine neoplasms. J Nucl Med 42:998–1004PubMed
Metadata
Title
Is hybrid imaging (SPECT/CT) a useful adjunct in the management of suspected facet joints arthropathy?
Authors
Hosam E. Matar
Shaunak Navalkissoor
Marko Berovic
Rohit Shetty
Nicholas Garlick
Adrian T. H. Casey
Ann-Marie Quigley
Publication date
01-05-2013
Publisher
Springer-Verlag
Published in
International Orthopaedics / Issue 5/2013
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-013-1811-y

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