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Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 4/2011

01-10-2011 | Materno-fetal Medicine

Is colonization with GBS in a previous pregnancy associated with adverse perinatal outcomes?

Authors: Adi Y. Weintraub, Roy Kessous, Ruslan Sergienko, Shimrit Salem Yaniv, Fernanda Press, Arnon Wiznitzer, Eyal Sheiner

Published in: Archives of Gynecology and Obstetrics | Issue 4/2011

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Abstract

Objective

To investigate whether colonization with GBS in a previous pregnancy is associated subsequently with adverse obstetric and perinatal outcomes.

Methods

A retrospective study was undertaken comparing pregnancy complications of patients with and without colonization with GBS in a previous pregnancy from 1988 to 2006. Women with a positive GBS culture in the current pregnancy, women lacking prenatal care and multiple gestations were excluded from the analysis.

Main outcome measures

Adverse obstetric and perinatal outcomes including premature rupture of membranes, intrapartum fever, chorioamnionitis and perinatal mortality.

Results

Out of 184,266 singleton deliveries, 230 (0.12%) were of patients with a positive GBS culture in their previous pregnancy. Previous GBS colonization was not found to be associated with adverse pregnancy outcomes such as PROM (9.1 vs. 6.8%; P = 0.16), intrapartum fever (1.3 vs. 2.2%; P = 0.72) and chorioamnionitis (1.3 vs. 0.8%; P = 0.29).

Conclusions

GBS colonization in a previous pregnancy is not associated with adverse pregnancy outcomes in the current pregnancy.
Literature
1.
Prevention of perinatal group B streptococcal disease: revised guideline from CDC. MMWR Recomm Rep 2002; 51(RR-11):1–22
2.
Baker CJ, Edwards MS (1995) Group B streptococcal infections. In: Remington TA, Klein JO (eds) Infectious diseases of the fetus and newborn, 4th edn. WB Saunders, Philadelphia, pp 980–1054
3.
Eidelman AI, Rudensky B, Turgeman D, Nubani N, Schimmel MS, Isachson M (1990) Epidemiology of perinatal group B streptococci colonization and disease in mothers and infants. Update of ongoing 10 years Jerusalem study. Isr J Med Sci 26:71–73PubMed
4.
Schimmel MS, Eidelman AI, Rudensky B (1994) Epidemiology of group B streptococcal colonization and infection in Jerusalem 1989–1991. Isr J Med Sci 30:349–351PubMed
5.
Schimmel MS, Samueloff A, Eidelman AI (1998) Prevention of neonatal group B streptococcal infections. Is there a rational prevention strategy? Clin Perinatol 25:687–697PubMed
6.
Eisenberg VH, Raveh D, Meislish Y, Rudensky B, Ezra Y, Samueloff A, Eidelman AI, Schimmel MS (2006) Prevention of early-onset neonatal group B streptococcal infection: is universal screening by culture universally applicable? Isr Med Assoc J 8(10):698–702PubMed
7.
Marchaim D, Gortzak-Uzan L, Peled N, Riesenberg K, Schlaeffer F (2003) Cell wall proteins of group B streptococcus, low incidence of neonatal disease in southern Israel. J Reprod Med 48(9):697–702PubMed
8.
Garland SM (1991) Early-onset neonatal group B streptococcus (GBS) infection: associated obstetric factors. Aust NZJ Obstet Gynaecol 31:117–118CrossRef
9.
Regan JA, Klebanoff MA, Nugent RP (1996) Colonization with group B Streptococci in pregnancy and adverse outcome. VIP Study Group. Am J Obstet Gynaecol 174:1354–1360CrossRef
10.
Moller M, Thomsen AC, Borch K (1984) Rupture of fetal membranes and premature delivery associated with group B streptococci in urine of pregnant women. Lancet 2:69–70PubMedCrossRef
11.
McDonald HM, O’Loughlin JA, Jolley P, Vigneswaran R, McDonald PJ (1991) Vaginal infection and preterm labor. Brit J Obstet Gynaecol 98:427–435CrossRef
12.
Schuchat A, Oxtoby M, Cochi S (1990) Population-based risk factors for neonatal group B streptococcal disease: results of a cohort study in metropolitan Atlanta. J Infect Dis 162:672–677PubMedCrossRef
13.
Gibbs RS, Schrag S, Schuchat A (2004) Perinatal infections due to group B streptococci. Obstet Gynecol 104:1062–1076PubMedCrossRef
14.
Rouse DJ, Goldenberg RL, Cliver SP, Cutter GR, Mennemeyer ST, Fargason CA Jr (1994) Strategies for the prevention of early-onset neonatal group B streptococcal sepsis: a decision analysis. Obstet Gynecol 83:483–494PubMedCrossRef
15.
Faxelius G, Bremme K, Christensen KK, Christensen P, Ringertz S (1988) Neonatal septicemia due to group B streptococci—perinatal risk factors and outcome of subsequent pregnancies. J Perinat Med 16:423–430PubMedCrossRef
16.
Christensen KK, Dahlander K, Linden V, Svenningsen N, Christensen P (1981) Obstetrical care in future pregnancies after fetal loss in group B streptococcal septicemia. A prevention program based on bacteriological and immunological follow-up. Eur J Obstet Gynecol Reprod Biol 12:143–150PubMedCrossRef
17.
Twizer I, Sheiner E, Hallak M, Mazor M, Katz M, Shoham-Vardi I (2001) Lack of prenatal care in a traditional society. Is it an obstetric hazard? J Reprod Med 46:662–668PubMed
18.
Sheiner E, Shoham-Vardi I, Weitzman D, Gohar J, Carmi R (1998) Decisions regarding pregnancy termination among Bedouin couples referred to third level ultrasound clinic. Eur J Obstet Gynecol Reprod Biol 76:141–146PubMedCrossRef
Metadata
Title
Is colonization with GBS in a previous pregnancy associated with adverse perinatal outcomes?
Authors
Adi Y. Weintraub
Roy Kessous
Ruslan Sergienko
Shimrit Salem Yaniv
Fernanda Press
Arnon Wiznitzer
Eyal Sheiner
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 4/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1724-6

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