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General Thoracic and Cardiovascular Surgery

10-04-2024 | Original Article

Is chest tube capnography effective in differentiating between true and false air leaks after minimally invasive thoracic surgery?

Authors: Giorgio Cannone, Alessio Campisi, Giovanni Maria Comacchio, Giulia Lorenzoni, Stefano Terzi, Alessandro Pangoni, Ivan Lomangino, Chiara Catelli, Federico Rea, Andrea Dell’Amore

Published in: General Thoracic and Cardiovascular Surgery

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Abstract

Objective

Air leak (AL) is the most frequent adverse event after thoracic surgery. When AL occurs, the concentration of the principal gas in the pleural space should be similar to that of air exhaled. Accordingly, we tried to develop a new method to identify AL by analyzing pCO2 levels in the air flow from the chest drainage using capnography.

Methods

This is a prospective observational study of 104 patients who underwent VATS surgery between January 2020 and July 2021. Digital drainage systems were used to detect AL.

Results

Eighty-two patients (79%) had lung resection. Among them, 19 had post-operative day 1 air leaks (median 67 ml/min). AL patients had higher intrapleural CO2 levels (median 24 mmHg) (p < 0.001). Median chest drainage duration was 2 days (range 1.0–3.0). Univariable logistic regression showed a linear and significant association between intrapleural CO2 levels and AL risk (OR 1.26, 95% CI 1.17–1.36, p < 0.001, C index: 0.94). The Univariable Gamma model demonstrated that an elevation in CO2 levels was linked to AL on POD1 (with an adjusted mean effect of 7.006, 95% CI 1.59–12.41, p = 0.011) and extended duration of drainage placement (p < 0.001).

Conclusions

Intrapleural CO2 could be an effective tool to assess AL. The linear association between variables allows us to hypothesize the role of CO2 in the identification of AL. Further studies should be performed to identify a CO2 cutoff that will standardize the management of chest drainage.
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Metadata
Title
Is chest tube capnography effective in differentiating between true and false air leaks after minimally invasive thoracic surgery?
Authors
Giorgio Cannone
Alessio Campisi
Giovanni Maria Comacchio
Giulia Lorenzoni
Stefano Terzi
Alessandro Pangoni
Ivan Lomangino
Chiara Catelli
Federico Rea
Andrea Dell’Amore
Publication date
10-04-2024
Publisher
Springer Nature Singapore
Published in
General Thoracic and Cardiovascular Surgery
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-024-02025-x