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Published in: Annals of General Psychiatry 1/2010

Open Access 01-04-2010 | Meeting abstract

Is amisulpride associated less with neuroleptic malignant syndrome? Review and hypothesis

Authors: Vaios Peritogiannis, Georgios Kalampokis, Charalampos Lixouriotis

Published in: Annals of General Psychiatry | Special Issue 1/2010

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Excerpt

Atypical antipsychotics have been reported to induce neuroleptic malignant syndrome (NMS). The precise pathophysiologic mechanism is unknown but dopamine blockage is pivotal. The serotoninergic action of atypical antipsychotics may also been implicated because serotonin may inhibit dopamine release and worsen hypodopaminergic states. Amisulpride, which is a selective D2/D3 receptor antagonist and has no affinity for serotonin receptors may be less associated with the development of NMS. …
Metadata
Title
Is amisulpride associated less with neuroleptic malignant syndrome? Review and hypothesis
Authors
Vaios Peritogiannis
Georgios Kalampokis
Charalampos Lixouriotis
Publication date
01-04-2010
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue Special Issue 1/2010
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/1744-859X-9-S1-S158

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