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01-03-2014 | Editorial and Commentary

Is a policy of watch and wait after a complete response following neoadjuvant treatment for locally advanced rectal adenocarcinoma justified? Should we reset the limit?

Authors: Carlo Eugenio Vitelli, Francesco Stipa, Ugo De Paula

Published in: Updates in Surgery | Issue 1/2014

Excerpt

Radical surgery has been considered, in the past century, the unique and more effective therapeutic option for locally advanced rectal adenocarcinoma. Standardization of surgical technique [1] has reduced the local recurrence rates to one digit percentages, and the addition of radiation therapy treatments combined with less toxic chemotherapy regimens either pre- or post-operatively has significantly improved the short- and long-term outcomes of these patients. The systematic use of neoadjuvant therapy has led to the common observation that at least 20–30 % of patients (depending on the CHT regimen used and the timing of surgery) are completely free of tumor (CR: ypT0ypN0) in the resected specimens [2, 3]. …

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Title: Is a policy of watch and wait after a complete response following neoadjuvant treatment for locally advanced rectal adenocarcinoma justified? Should we reset the limit?
Authors: Carlo Eugenio Vitelli
Francesco Stipa
Ugo De Paula
Publication date: 01-03-2014
Publisher: Springer Milan
Published in: Updates in Surgery / Issue 1/2014
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI: https://doi.org/10.1007/s13304-013-0239-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Is a policy of watch and wait after a complete response following neoadjuvant treatment for locally advanced rectal adenocarcinoma justified? Should we reset the limit?

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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