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Critical Care
Published in: Critical Care 1/2015

Open Access 01-12-2015 | Letter

Ionized calcium measurements during regional citrate anticoagulation in CRRT: we need better blood gas analyzers

Authors: Detlef Kindgen-Milles, Marlies Ostermann, Torsten Slowinski

Published in: Critical Care | Issue 1/2015

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Excerpt

Schwarzer et al. [1] showed discrepant postfilter ionized calcium concentrations [iCa] when using different blood gas analyzers (BGAs) and called for a change of the Fresenius regional citrate anticoagulation (RCA) protocol to ensure patient safety. Of note, precision of the BGAs was not tested. …
Literature
1.
Schwarzer P, Kuhn S-O, Stracke S, Grundling M, Knigge S, et al. Discrepant post filter ionized calcium concentrations by common blood gas analyzers in CRRT using regional citrate anticoagulation. Crit Care. 2015;19:321.CrossRef
2.
Kalb R, Kram R, Morgera S, Slowinski T, Kindgen-Milles D. Regional citrate anticoagulation for high volume continuous venovenous hemodialysis in surgical patients with high bleeding risk. Ther Apher Dial. 2013;17:202–12.CrossRef
3.
Khadzhynov D, Schelter C, Lieker I, Mika A, Staeck O, et al. Incidence and outcome of metabolic disarrangements consistent with citrate accumulation in critically ill patients undergoing continuous venovenous hemodialysis with regional citrate anticoagulation. J Crit Care. 2014;29:265–71.CrossRef
4.
Morgera S, Schneider M, Slowinski T, Vargas-Hein O, Zuckermann-Becker H, et al. A safe citrate anticoagulation protocol with variable treatment efficacy and excellent control of the acid-base status. Crit Care Med. 2009;37:2018–24.CrossRef
5.
Slowinski T, Morgera S, Joannidis M, Henneberg T, Stocker R, et al. Safety and efficacy of regional citrate anticoagulation in continuous veno-venous hemodialysis in the presence of liver failure: The Liver Citrate Anticoagulation Threshold (L-CAT)—an observational study. Crit Care. 2015;19:349.CrossRef
Metadata
Title
Ionized calcium measurements during regional citrate anticoagulation in CRRT: we need better blood gas analyzers
Authors
Detlef Kindgen-Milles
Marlies Ostermann
Torsten Slowinski
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2015
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-015-1143-y

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