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Journal of Ophthalmic Inflammation and Infection

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Open Access 01-12-2016 | Brief report

Intravitreal dexamethasone implant for the treatment of cystoid macular oedema associated with acute retinal necrosis

Authors: Parthopratim Dutta Majumder, Jyotirmay Biswas, Asra Ambreen, Rowayda Amin, Zahedur Rahman Pannu, Ahmed Magdy Bedda

Published in: Journal of Ophthalmic Inflammation and Infection | Issue 1/2016

Abstract

Background

Acute retinal necrosis is a rare but devastating ocular condition. We report two cases of acute retinal necrosis in immunocompetent patients, complicated by cystoid macular oedema and treated with intravitreal dexamethasone (OZURDEX®) implant.

Results

Two patients diagnosed with acute retinal necrosis were treated with intravenous acyclovir. Both of them developed cystoid macular oedema following resolution of viral retinitis. Ocular condition of the first patient was further complicated by central serous chorioretinopathy. Under unavoidable circumstances, cystoid macular oedema in both the patients was treated with intravitreal dexamethasone implant with great caution. Resolution of cystoid macular oedema without recurrence of viral retinitis was noted in the long-term follow-up.

Conclusions

Findings of the case report should be interpreted cautiously, and extreme caution should be exercised prior deciding the management with a corticosteroid implant in patients with viral retinitis. However, intravitreal dexamethasone implant can be a useful option in selected patients with cystoid macular oedema in acute retinal necrosis.

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Title: Intravitreal dexamethasone implant for the treatment of cystoid macular oedema associated with acute retinal necrosis
Authors: Parthopratim Dutta Majumder
Jyotirmay Biswas
Asra Ambreen
Rowayda Amin
Zahedur Rahman Pannu
Ahmed Magdy Bedda
Publication date: 01-12-2016
Publisher: Springer Berlin Heidelberg
Published in: Journal of Ophthalmic Inflammation and Infection / Issue 1/2016
Electronic ISSN: 1869-5760
DOI: https://doi.org/10.1186/s12348-016-0116-x

At a glance: The STEP trials

Springer Medicine

Intravitreal dexamethasone implant for the treatment of cystoid macular oedema associated with acute retinal necrosis

Abstract

Background

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Results

Conclusions

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