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Published in: Journal of Neurology 6/2014

01-06-2014 | Review

Intravenous tenecteplase in acute ischemic stroke: an updated review

Author: Réza Behrouz

Published in: Journal of Neurology | Issue 6/2014

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Abstract

Tenecteplase in a genetically engineered variant of alteplase. Although the two have the same mechanism of action, tenecteplase has properties that makes it a seemingly more advantageous thrombolytic. Because of its rapid single-bolus administration, its use is favored over alteplase in the treatment of acute myocardial infarction. Over the past few years, several clinical studies have been conducted to assess the safety, feasibility, and efficacy of tenecteplase in ischemic stroke. In spite of the mixed results of these studies, experimentation with tenecteplase continues in from of clinical trials. In this article, the utility of tenecteplase in ischemic stroke will be discussed.
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Metadata
Title
Intravenous tenecteplase in acute ischemic stroke: an updated review
Author
Réza Behrouz
Publication date
01-06-2014
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology / Issue 6/2014
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-013-7102-0

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