Skip to main content
Top
Published in: Diagnostic Pathology 1/2008

Open Access 01-12-2008 | Short report

Intravascular lesions of the hand

Authors: Liron Pantanowitz, Wayne H Duke

Published in: Diagnostic Pathology | Issue 1/2008

Login to get access

Abstract

Introduction

Intravascular lesions of the hand comprise reactive and neoplastic entities. The clinical diagnosis of such lesions is often difficult, and usually requires pathologic examination. We present the largest series to date of intravascular lesions affecting the hand.

Methods

A retrospective review of intravascular (arterial and venous) lesions involving the hand was conducted. Data regarding clinicopathologic findings were analyzed.

Results

We identified 10 patients with intravascular lesions of their hands including thromboemboli (n = 3), reactive intravascular conditions such as papillary endothelial hyperplasia or Masson's tumor (n = 2) and fasciitis (n = 1), as well as vascular neoplasms including pyogenic granuloma (n = 2) and angioleiomyoma (n = 2).

Conclusion

Blood vessel injury and/or venous thrombosis may predispose to several intravascular lesions of the hand. Recognition of reactive entities from neoplastic conditions is important.
Appendix
Available only for authorised users
Literature
1.
go back to reference Fleming AN, Smith PJ: Vascular cell tumors of the hand in children. Hand Clin. 2000, 16: 609-24.PubMed Fleming AN, Smith PJ: Vascular cell tumors of the hand in children. Hand Clin. 2000, 16: 609-24.PubMed
2.
go back to reference Julliard FA, Baviera EE: Benign lesions of the hand simulating angiosarcoma: Masson's vegetating intravascular hemangioendothelioma (Article in French). Ann Chir Main. 1983, 2: 59-61. 10.1016/S0753-9053(83)80082-9.CrossRefPubMed Julliard FA, Baviera EE: Benign lesions of the hand simulating angiosarcoma: Masson's vegetating intravascular hemangioendothelioma (Article in French). Ann Chir Main. 1983, 2: 59-61. 10.1016/S0753-9053(83)80082-9.CrossRefPubMed
3.
go back to reference Anand A, Tsapakis EM, Narvani AA, Alhakim A, Cannon SR, Tsiridis E: "Pseudosarcoma" in a pregnant woman. World J Surg Oncol. 2007, 18: 5-7. Anand A, Tsapakis EM, Narvani AA, Alhakim A, Cannon SR, Tsiridis E: "Pseudosarcoma" in a pregnant woman. World J Surg Oncol. 2007, 18: 5-7.
4.
go back to reference Kocer U, Aksoy HM, Tiftikcioglu YO, Karaaslan O: Intravenous pyogenic granuloma of the hand. Dermatol Surg. 2003, 29: 974-6. 10.1046/j.1524-4725.2003.29263.x.PubMed Kocer U, Aksoy HM, Tiftikcioglu YO, Karaaslan O: Intravenous pyogenic granuloma of the hand. Dermatol Surg. 2003, 29: 974-6. 10.1046/j.1524-4725.2003.29263.x.PubMed
5.
go back to reference Hung CH, Kuo HW, Chiu YK, Huang PH: Intravascular pyogenic granuloma arising in an acquired arteriovenous malformation: report of a case and review of the literature. Dermatol Surg. 2004, 30: 1050-3. 10.1111/j.1524-4725.2004.30316.x.PubMed Hung CH, Kuo HW, Chiu YK, Huang PH: Intravascular pyogenic granuloma arising in an acquired arteriovenous malformation: report of a case and review of the literature. Dermatol Surg. 2004, 30: 1050-3. 10.1111/j.1524-4725.2004.30316.x.PubMed
6.
go back to reference Borrelli L, Ciniglio M, Maffulli N, Del Torto M: Intravascular papillary endothelial hyperplasia in the hand of a fencer. Pathologica. 1992, 84: 551-6.PubMed Borrelli L, Ciniglio M, Maffulli N, Del Torto M: Intravascular papillary endothelial hyperplasia in the hand of a fencer. Pathologica. 1992, 84: 551-6.PubMed
7.
go back to reference Kadwa AM, Robbs JV: Gangrenous fingers: the tip of the iceberg. J R Coll Surg Edinb. 1990, 35: 71-4.PubMed Kadwa AM, Robbs JV: Gangrenous fingers: the tip of the iceberg. J R Coll Surg Edinb. 1990, 35: 71-4.PubMed
8.
go back to reference Pruitt A, Dodson TF, Najibi S, Thourani V, Sherman A, Cloft H, Caliendo A, Smith RB: Distal septic emboli and fatal brachiocephalic artery mycotic pseudoaneurysm as a complication of stenting. J Vasc Surg. 2002, 36: 625-8. 10.1067/mva.2002.127340.CrossRefPubMed Pruitt A, Dodson TF, Najibi S, Thourani V, Sherman A, Cloft H, Caliendo A, Smith RB: Distal septic emboli and fatal brachiocephalic artery mycotic pseudoaneurysm as a complication of stenting. J Vasc Surg. 2002, 36: 625-8. 10.1067/mva.2002.127340.CrossRefPubMed
9.
go back to reference Gundes H, Tosun B, Alici T, Buluc L, Arpaci A: Upper-extremity digital amputation secondary to non-traumatic ischemia. Orthopedics. 2005, 28: 697-9.PubMed Gundes H, Tosun B, Alici T, Buluc L, Arpaci A: Upper-extremity digital amputation secondary to non-traumatic ischemia. Orthopedics. 2005, 28: 697-9.PubMed
10.
go back to reference Rippey JJ: General Pathology. 1994, Johannesburg: Witwatersrand University Press, 103-114. Rippey JJ: General Pathology. 1994, Johannesburg: Witwatersrand University Press, 103-114.
11.
go back to reference Guarda LA, Borrero JL: Hand and digital ischemia due to arteriosclerosis and thromboembolization in young adults: pathologic features with clinical correlations. Mod Pathol. 1990, 3: 654-8.PubMed Guarda LA, Borrero JL: Hand and digital ischemia due to arteriosclerosis and thromboembolization in young adults: pathologic features with clinical correlations. Mod Pathol. 1990, 3: 654-8.PubMed
12.
go back to reference Kuo T, Sayers CP, Rosai J: Masson's "vegetant intravascular hemangioendothelioma:" a lesion often mistaken for angiosarcoma: study of seventeen cases located in the skin and soft tissues. Cancer. 1976, 38: 1227-36. 10.1002/1097-0142(197609)38:3<1227::AID-CNCR2820380324>3.0.CO;2-6.CrossRefPubMed Kuo T, Sayers CP, Rosai J: Masson's "vegetant intravascular hemangioendothelioma:" a lesion often mistaken for angiosarcoma: study of seventeen cases located in the skin and soft tissues. Cancer. 1976, 38: 1227-36. 10.1002/1097-0142(197609)38:3<1227::AID-CNCR2820380324>3.0.CO;2-6.CrossRefPubMed
13.
go back to reference Wehbé MA, Otto NR: Intravascular papillary endothelial hyperplasia in the hand. J Hand Surg [Am]. 1986, 11: 275-9.CrossRef Wehbé MA, Otto NR: Intravascular papillary endothelial hyperplasia in the hand. J Hand Surg [Am]. 1986, 11: 275-9.CrossRef
14.
go back to reference Katzman B, Caligiuri DA, Klein DM, Nicastri AD, Chen P: Recurrent intravascular papillary endothelial hyperplasia. J Hand Surg [Br]. 1997, 22: 113-5.CrossRef Katzman B, Caligiuri DA, Klein DM, Nicastri AD, Chen P: Recurrent intravascular papillary endothelial hyperplasia. J Hand Surg [Br]. 1997, 22: 113-5.CrossRef
15.
go back to reference Tokyol C, Demir Y, Aktepe F: Cutaneous intravascular papillary endothelial hyperplasia of the hand: a case report and review of the literature. Turk J Pediatr. 2005, 47: 71-4.PubMed Tokyol C, Demir Y, Aktepe F: Cutaneous intravascular papillary endothelial hyperplasia of the hand: a case report and review of the literature. Turk J Pediatr. 2005, 47: 71-4.PubMed
16.
go back to reference Erol O, Ozçakar L, Uygur F, Keçik A, Ozkaya O: Intravascular papillary endothelial hyperplasia in the finger: not a premier diagnosis. J Cutan Pathol. 2007, 34: 806-7. 10.1111/j.1600-0560.2006.00689.x.CrossRefPubMed Erol O, Ozçakar L, Uygur F, Keçik A, Ozkaya O: Intravascular papillary endothelial hyperplasia in the finger: not a premier diagnosis. J Cutan Pathol. 2007, 34: 806-7. 10.1111/j.1600-0560.2006.00689.x.CrossRefPubMed
17.
go back to reference Sangueza OP, Requena L: Pathology of vascular skin lesions. 2003, New Jersey: Humana Press, 99-131.CrossRef Sangueza OP, Requena L: Pathology of vascular skin lesions. 2003, New Jersey: Humana Press, 99-131.CrossRef
18.
go back to reference Reed CN, Cooper PH, Swerlick RA: Intravascular papillary endothelial hyperplasia. Multiple lesions simulating Kaposi's sarcoma. J Am Acad Dermatol. 1984, 10: 110-3.CrossRefPubMed Reed CN, Cooper PH, Swerlick RA: Intravascular papillary endothelial hyperplasia. Multiple lesions simulating Kaposi's sarcoma. J Am Acad Dermatol. 1984, 10: 110-3.CrossRefPubMed
19.
go back to reference Patchefsky AS, Enzinger FM: Intravascular fasciitis: a report of 17 cases. Am J Surg Pathol. 1981, 5: 29-36.CrossRefPubMed Patchefsky AS, Enzinger FM: Intravascular fasciitis: a report of 17 cases. Am J Surg Pathol. 1981, 5: 29-36.CrossRefPubMed
20.
go back to reference Ito M, Matsunaga K, Sano K, Sakaguchi N, Hotchi M: Intravascular fasciitis of the forearm vein: a case report with immunohistochemical characterization. Pathol Int. 1999, 49: 175-9. 10.1046/j.1440-1827.1999.00842.x.CrossRefPubMed Ito M, Matsunaga K, Sano K, Sakaguchi N, Hotchi M: Intravascular fasciitis of the forearm vein: a case report with immunohistochemical characterization. Pathol Int. 1999, 49: 175-9. 10.1046/j.1440-1827.1999.00842.x.CrossRefPubMed
21.
go back to reference Anderson WJ: Intravenous pyogenic granuloma of the hand. J Hand Surg [Am]. 1985, 10: 728-9.CrossRef Anderson WJ: Intravenous pyogenic granuloma of the hand. J Hand Surg [Am]. 1985, 10: 728-9.CrossRef
22.
go back to reference DiFazio F, Mogan J: Intravenous pyogenic granuloma of the hand. J Hand Surg [Am]. 1989, 14: 310-2. 10.1016/0363-5023(89)90028-2.CrossRef DiFazio F, Mogan J: Intravenous pyogenic granuloma of the hand. J Hand Surg [Am]. 1989, 14: 310-2. 10.1016/0363-5023(89)90028-2.CrossRef
23.
go back to reference Cooper PH, McAllister HA, Helwig EB: Intravenous pyogenic granuloma. A study of 18 cases. Am J Surg Pathol. 1979, 3: 221-8.CrossRefPubMed Cooper PH, McAllister HA, Helwig EB: Intravenous pyogenic granuloma. A study of 18 cases. Am J Surg Pathol. 1979, 3: 221-8.CrossRefPubMed
24.
go back to reference Inalöz HS, Patel G, Knight AG: Recurrent intravascular papillary endothelial hyperplasia developing from a pyogenic granuloma. J Eur Acad Dermatol Venereol. 2001, 15: 156-8. 10.1046/j.1468-3083.2001.00228.x.CrossRefPubMed Inalöz HS, Patel G, Knight AG: Recurrent intravascular papillary endothelial hyperplasia developing from a pyogenic granuloma. J Eur Acad Dermatol Venereol. 2001, 15: 156-8. 10.1046/j.1468-3083.2001.00228.x.CrossRefPubMed
25.
go back to reference Uchida M, Kojima T, Hirase Y, Iizuka T: Clinical characteristics of vascular leiomyoma of the upper extremity: report of 11 cases. Br J Plast Surg. 1992, 45: 547-9. 10.1016/0007-1226(92)90153-O.CrossRefPubMed Uchida M, Kojima T, Hirase Y, Iizuka T: Clinical characteristics of vascular leiomyoma of the upper extremity: report of 11 cases. Br J Plast Surg. 1992, 45: 547-9. 10.1016/0007-1226(92)90153-O.CrossRefPubMed
26.
go back to reference Hwang JW, Ahn JM, Kang HS, Suh JS, Kim SM, Seo JW: Vascular leiomyoma of an extremity: MR imaging-pathology correlation. AJR Am J Roentgenol. 1998, 171: 981-5.CrossRefPubMed Hwang JW, Ahn JM, Kang HS, Suh JS, Kim SM, Seo JW: Vascular leiomyoma of an extremity: MR imaging-pathology correlation. AJR Am J Roentgenol. 1998, 171: 981-5.CrossRefPubMed
27.
go back to reference Sajben FP, Barnette DJ, Barrett TL: Intravascular angioleiomyoma. J Cutan Pathol. 1999, 26: 165-7. 10.1111/j.1600-0560.1999.tb01823.x.CrossRefPubMed Sajben FP, Barnette DJ, Barrett TL: Intravascular angioleiomyoma. J Cutan Pathol. 1999, 26: 165-7. 10.1111/j.1600-0560.1999.tb01823.x.CrossRefPubMed
28.
go back to reference Hashimoto H, Quade B: Angioleiomyoma. Tumours of soft tissue and bone. Edited by: Fletcher CDM, Unni K, Mertens F. 2002, IARC Press, Lyon, 128-129. Hashimoto H, Quade B: Angioleiomyoma. Tumours of soft tissue and bone. Edited by: Fletcher CDM, Unni K, Mertens F. 2002, IARC Press, Lyon, 128-129.
29.
go back to reference Luzar B, Antony F, Ramdial PK, Calonje E: Intravascular Kaposi's sarcoma – a hitherto unrecognized phenomenon. J Cutan Pathol. 2007, 34: 861-4. 10.1111/j.1600-0560.2007.00734.x.CrossRefPubMed Luzar B, Antony F, Ramdial PK, Calonje E: Intravascular Kaposi's sarcoma – a hitherto unrecognized phenomenon. J Cutan Pathol. 2007, 34: 861-4. 10.1111/j.1600-0560.2007.00734.x.CrossRefPubMed
30.
go back to reference McMenamin ME, Calonje E: Intravascular myopericytoma. J Cutan Pathol. 2002, 29: 557-561. 10.1034/j.1600-0560.2002.290908.x.CrossRefPubMed McMenamin ME, Calonje E: Intravascular myopericytoma. J Cutan Pathol. 2002, 29: 557-561. 10.1034/j.1600-0560.2002.290908.x.CrossRefPubMed
Metadata
Title
Intravascular lesions of the hand
Authors
Liron Pantanowitz
Wayne H Duke
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2008
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-3-24

Other articles of this Issue 1/2008

Diagnostic Pathology 1/2008 Go to the issue