Skip to main content
Top
Published in: Child's Nervous System 2/2013

01-02-2013 | Case Report

Intramedullary spinal cord cavernous malformations presenting with unexplained chest pain: case report and review of the literature

Authors: Salvatore Savasta, Mattia Algeri, Elisabetta De Sando, Alessandro Lozza, Georgia Mussati, Davide Locatelli, Gian Luigi Marseglia

Published in: Child's Nervous System | Issue 2/2013

Login to get access

Abstract

Introduction

Intramedullary spinal cord cavernous malformations are very uncommon in pediatric age, with only 26 cases reported within the available literature to date. The diagnosis of such lesions is often difficult and delayed because of their rarity and bizarre clinical presentation.

Case report

We report a case of intramedullary spinal cord cavernous malformation in a girl, in which sudden onset chest pain was the only presenting symptom, followed by appearance of neurological deficits after 5 days. We review the available literature discussing clinical features and principles of management of these lesions in children.
Literature
1.
go back to reference Khalatbari MR, Hamidi M, Moharamzad Y (2011) Pediatric intramedullary cavernous malformation of the conus medullaris: case report and review of the literature. Childs Nerv Syst 27(3):507–511PubMedCrossRef Khalatbari MR, Hamidi M, Moharamzad Y (2011) Pediatric intramedullary cavernous malformation of the conus medullaris: case report and review of the literature. Childs Nerv Syst 27(3):507–511PubMedCrossRef
2.
go back to reference Kharkar S, Shuck J, Conway J, Rigamonti D (2007) The natural history of conservatively managed symptomatic intramedullary spinal cord cavernomas. Neurosurgery 60:865–872PubMedCrossRef Kharkar S, Shuck J, Conway J, Rigamonti D (2007) The natural history of conservatively managed symptomatic intramedullary spinal cord cavernomas. Neurosurgery 60:865–872PubMedCrossRef
3.
go back to reference Sandalcioglu IE, Wiedemayer H, Gasser T, Asgari S, Engelhorn T, Stolke D (2003) Intramedullary spinal cord cavernous malformation: clinical features and risk of hemorrhage. Neurosurg Rev 26:253–256PubMedCrossRef Sandalcioglu IE, Wiedemayer H, Gasser T, Asgari S, Engelhorn T, Stolke D (2003) Intramedullary spinal cord cavernous malformation: clinical features and risk of hemorrhage. Neurosurg Rev 26:253–256PubMedCrossRef
4.
go back to reference Bakir A, Savas A, Yilmaz E, Savaş B, Erden E, Cağlar S, Sener O (2006) Spinal intradural-intramedullary cavernous malformation: case report and literature review. Pediatr Neurosurg 42:35–37PubMedCrossRef Bakir A, Savas A, Yilmaz E, Savaş B, Erden E, Cağlar S, Sener O (2006) Spinal intradural-intramedullary cavernous malformation: case report and literature review. Pediatr Neurosurg 42:35–37PubMedCrossRef
5.
go back to reference Narayan P, Barrow DL (2003) Intramedullary spinal cavernous malformation following spinal irradiation. Case report and review of the literature. J Neurosurg 98:68–72PubMed Narayan P, Barrow DL (2003) Intramedullary spinal cavernous malformation following spinal irradiation. Case report and review of the literature. J Neurosurg 98:68–72PubMed
6.
go back to reference Anson JA, Spetzler RF (1993) Surgical resection of intramedullary spinal cord cavernous malformations. J Neurosurg 78:446–451PubMedCrossRef Anson JA, Spetzler RF (1993) Surgical resection of intramedullary spinal cord cavernous malformations. J Neurosurg 78:446–451PubMedCrossRef
7.
go back to reference Varoglu AO, Tan H, Onbas O, Tuzun Y, Deniz O, Gursan N (2008) Intramedullary angioma with bilateral arm hypothermia. Br J Neurosurg 22:687–689PubMedCrossRef Varoglu AO, Tan H, Onbas O, Tuzun Y, Deniz O, Gursan N (2008) Intramedullary angioma with bilateral arm hypothermia. Br J Neurosurg 22:687–689PubMedCrossRef
8.
go back to reference Marseglia GL, Savasta S, Ravelli A, Gaino TM, Burgio GR (1995) Recurrent chest pain as the presenting manifestation of spinal meningioma. Acta Paediatr 84:1086–1088PubMedCrossRef Marseglia GL, Savasta S, Ravelli A, Gaino TM, Burgio GR (1995) Recurrent chest pain as the presenting manifestation of spinal meningioma. Acta Paediatr 84:1086–1088PubMedCrossRef
9.
go back to reference Selbst SM (2010) Approach to the child with chest pain. Pediatr Clin N Am 57(6):1221–1234CrossRef Selbst SM (2010) Approach to the child with chest pain. Pediatr Clin N Am 57(6):1221–1234CrossRef
10.
go back to reference Hussain MZ, Ishrat S, Salehuddin M, Mahmood M, Islam MT (2011) Chest pain in children: an update. Mymensingh Med J 20(1):165–167PubMed Hussain MZ, Ishrat S, Salehuddin M, Mahmood M, Islam MT (2011) Chest pain in children: an update. Mymensingh Med J 20(1):165–167PubMed
11.
go back to reference Noudel R, Litrè F, Vinchon M, Patey M, Rousseaux P (2008) Intramedullary spinal cord cavernous angioma in children: case report and literature review. Childs Nerv Syst 24(2):259–263PubMedCrossRef Noudel R, Litrè F, Vinchon M, Patey M, Rousseaux P (2008) Intramedullary spinal cord cavernous angioma in children: case report and literature review. Childs Nerv Syst 24(2):259–263PubMedCrossRef
12.
go back to reference Cornips E, Vinken P, Ter Laak-Poort M, Beuls EA, Weber J, Vles JS (2010) Intramedullary cavernoma presenting with hematomyelia: report of two girls. Childs Nerv Syst 26:391–398PubMedCrossRef Cornips E, Vinken P, Ter Laak-Poort M, Beuls EA, Weber J, Vles JS (2010) Intramedullary cavernoma presenting with hematomyelia: report of two girls. Childs Nerv Syst 26:391–398PubMedCrossRef
13.
go back to reference Nagib MG, O’Fallon MT (2002) Intramedullary cavernous angiomas of the spinal cord in the pediatric age group: a pediatric series. Pediatr Neurosurg 36:57–63PubMedCrossRef Nagib MG, O’Fallon MT (2002) Intramedullary cavernous angiomas of the spinal cord in the pediatric age group: a pediatric series. Pediatr Neurosurg 36:57–63PubMedCrossRef
14.
go back to reference Ogilvy CS, Louis DN, Ojemann RG (1992) Intramedullary cavernous angiomas of the spinal cord: clinical presentation, pathological features, and surgical management. Neurosurgery 31:219–229PubMedCrossRef Ogilvy CS, Louis DN, Ojemann RG (1992) Intramedullary cavernous angiomas of the spinal cord: clinical presentation, pathological features, and surgical management. Neurosurgery 31:219–229PubMedCrossRef
15.
go back to reference Gross BA, Du R, Popp AJ, Day AL (2010) Intramedullary spinal cord cavernous malformations. Neurosurg Focus 29(3):E14PubMedCrossRef Gross BA, Du R, Popp AJ, Day AL (2010) Intramedullary spinal cord cavernous malformations. Neurosurg Focus 29(3):E14PubMedCrossRef
16.
go back to reference Chen C-C, Wang C-M, Chu N-K, Wu KP-H, Tang SF-T, Wong AM-K (2008) Spinal cord arteriovenous malformation presenting as chest pain in a child. Spinal Cord 46:456–458PubMedCrossRef Chen C-C, Wang C-M, Chu N-K, Wu KP-H, Tang SF-T, Wong AM-K (2008) Spinal cord arteriovenous malformation presenting as chest pain in a child. Spinal Cord 46:456–458PubMedCrossRef
17.
go back to reference Jallo GI, Freed D, Zareck M, Epstein F, Kothbauer KF (2006) Clinical presentation and optimal management for intramedullary cavernous malformation. Neurosurg Focus 21:E10PubMedCrossRef Jallo GI, Freed D, Zareck M, Epstein F, Kothbauer KF (2006) Clinical presentation and optimal management for intramedullary cavernous malformation. Neurosurg Focus 21:E10PubMedCrossRef
18.
go back to reference Scott RM, Barnes P, Kupsky W, Adelman LS (1992) Cavernous angiomas of the central nervous system in children. J Neurosurg 76:38–46PubMedCrossRef Scott RM, Barnes P, Kupsky W, Adelman LS (1992) Cavernous angiomas of the central nervous system in children. J Neurosurg 76:38–46PubMedCrossRef
19.
go back to reference Kolias AG, Debasish P, Aditya S, Azzam I, Atul T (2009) Paediatric intramedullary spinal cord cavernous malformation: case report and review of the literature. Clin Neurol Neurosurg 111:784–788PubMedCrossRef Kolias AG, Debasish P, Aditya S, Azzam I, Atul T (2009) Paediatric intramedullary spinal cord cavernous malformation: case report and review of the literature. Clin Neurol Neurosurg 111:784–788PubMedCrossRef
20.
go back to reference McGirt MJ, Chaichana KL, Atiba A, Bydon A, Witham TF, Yao KC, Jallo GI (2008) Incidence of spinal deformity after resection of intramedullary spinal cord tumors in children who underwent laminectomy compared with laminoplasty. J Neurosurg Pediatr 1(1):57–62PubMedCrossRef McGirt MJ, Chaichana KL, Atiba A, Bydon A, Witham TF, Yao KC, Jallo GI (2008) Incidence of spinal deformity after resection of intramedullary spinal cord tumors in children who underwent laminectomy compared with laminoplasty. J Neurosurg Pediatr 1(1):57–62PubMedCrossRef
Metadata
Title
Intramedullary spinal cord cavernous malformations presenting with unexplained chest pain: case report and review of the literature
Authors
Salvatore Savasta
Mattia Algeri
Elisabetta De Sando
Alessandro Lozza
Georgia Mussati
Davide Locatelli
Gian Luigi Marseglia
Publication date
01-02-2013
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 2/2013
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-012-1941-3

Other articles of this Issue 2/2013

Child's Nervous System 2/2013 Go to the issue