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BMC Nephrology
Published in: BMC Nephrology 1/2009

Open Access 01-12-2009 | Study protocol

Intradialytic versus home based exercise training in hemodialysis patients: a randomised controlled trial

Authors: Kirsten P Koh, Robert G Fassett, James E Sharman, Jeff S Coombes, Andrew D Williams

Published in: BMC Nephrology | Issue 1/2009

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Abstract

Background

Exercise training in hemodialysis patients improves fitness, physical function, quality of life and markers of cardiovascular disease such as arterial stiffness. The majority of trials investigating this area have used supervised exercise training during dialysis (intradialytic), which may not be feasible for some renal units. The aim of this trial is to compare the effects of supervised intradialytic with unsupervised home-based exercise training on physical function and arterial stiffness.

Methods and design

This is a randomised, controlled clinical trial. A total of 72 hemodialysis patients will be randomised to receive either six months of intradialytic exercise training, home-based exercise training or usual care. Intradialytic patients will undergo three training sessions per week on a cycle ergometer and home-based patients will be provided with a walking program to achieve the same weekly physical activity. Primary outcome measures are six-minute walk distance (6 MWD) and aortic pulse wave velocity (PWV). Secondary outcome measures include augmentation index, peripheral and central blood pressures, physical activity and self-reported health. Measures will be made at baseline, three and six months.

Discussion

The results of this study will help determine the efficacy of home-based exercise training in hemodialysis patients. This may assist in developing exercise guidelines specific for these patients.

Trial Registration

ACTRN12608000247370
Appendix
Available only for authorised users
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Metadata
Title
Intradialytic versus home based exercise training in hemodialysis patients: a randomised controlled trial
Authors
Kirsten P Koh
Robert G Fassett
James E Sharman
Jeff S Coombes
Andrew D Williams
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Nephrology / Issue 1/2009
Electronic ISSN: 1471-2369
DOI
https://doi.org/10.1186/1471-2369-10-2

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