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Trials
Published in: Trials 1/2022

Open Access 01-12-2022 | Intracranial Hypertension | Study protocol

Rapid chest compression effects on intracranial pressure in patients with acute cerebral injury

Authors: Ricardo Miguel Rodrigues-Gomes, Joan-Daniel Martí, Rosa Martínez Rolán, Miguel Gelabert-González

Published in: Trials | Issue 1/2022

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Abstract

Background

Patients with acute brain injury often require invasive mechanical ventilation, increasing the risk of developing complications such as respiratory secretions retention. Rapid chest compression is a manual chest physiotherapy technique that aims to improve clearance of secretions in these patients. However, the rapid chest compression technique has been suggested to be associated with increased intracranial pressure in patients with acute brain injury. The aim of this work is to elucidate the effects of the technique on intracranial pressure in mechanically ventilated patients with acute brain injury. Furthermore, the effects of the technique in different volumes and flows recorded by the ventilator and the relationship between the pressure applied in the intervention group and the different variables will also be studied.

Methods

Randomized clinical trial, double-blinded. Patients with acute brain injury on invasive mechanical ventilation > 48 h will be included and randomized in two groups. In the control group, a technique of passive hallux mobilization will be applied, and in the intervention group, it will be performed using the rapid chest compression technique. Intracranial pressure (main variable) will be collected with an intracranial pressure monitoring system placed at the lateral ventricles (Integra Camino).

Discussion

The safety of chest physiotherapy techniques in patients at risk of intracranial hyperpressure is still uncertain. The aim of this study is to identify if the rapid manual chest compression technique is safe in ventilated patients with acute brain injury.

Trial registration

NCT03609866. Registered on 08/01/2018.
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Metadata
Title
Rapid chest compression effects on intracranial pressure in patients with acute cerebral injury
Authors
Ricardo Miguel Rodrigues-Gomes
Joan-Daniel Martí
Rosa Martínez Rolán
Miguel Gelabert-González
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Trials / Issue 1/2022
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-022-06189-w

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