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Published in: Acta Neurochirurgica 12/2009

01-12-2009 | Case Report

Intra-sellar schwannoma co-existing with GH-secreting pituitary adenoma

Authors: Maria Koutourousiou, Andreas Seretis, George Kontogeorgos

Published in: Acta Neurochirurgica | Issue 12/2009

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Abstract

Background

We present a unique example of an intra-sellar schwannoma co-existing with a growth hormone (GH)-secreting pituitary adenoma.

Method and Findings

The patient presented with acromegaly and magnetic resonance imaging (MRI) revealed an intra-sellar mass. The tumour was totally resected via a sub-labial trans-sphenoidal approach. Histopathology demonstrated the presence of a GH-secreting adenoma as well as a schwannoma at the periphery of the adenoma. After surgical excision, remission of the acromegaly occurred. Follow-up monitoring showed no evidence of recurrence of the adenoma two years after surgery.

Conclusion

To the best of our knowledge, this is the first example of an intra-sellar schwannoma co-existing with a GH-secreting pituitary adenoma.
Literature
1.
go back to reference Bleys RLAW, Janssen LM, Groen GJ (2001) The lateral sellar nerve plexus and its connections in humans. J Neurosurg 95:102–110CrossRefPubMed Bleys RLAW, Janssen LM, Groen GJ (2001) The lateral sellar nerve plexus and its connections in humans. J Neurosurg 95:102–110CrossRefPubMed
5.
go back to reference Esposito F, Cappabianca P, Del Basso De Caro M, Cavallo LM, Rinaldi C, de Divitiis E (2004) Endoscopic endonasal trans-sphenoidal removal of an intra-suprasellar schwannoma mimicking a pituitary adenoma. Minim Invasive Neurosurg 47(4):230–234. doi:10.1055/s-2004-818524 CrossRefPubMed Esposito F, Cappabianca P, Del Basso De Caro M, Cavallo LM, Rinaldi C, de Divitiis E (2004) Endoscopic endonasal trans-sphenoidal removal of an intra-suprasellar schwannoma mimicking a pituitary adenoma. Minim Invasive Neurosurg 47(4):230–234. doi:10.​1055/​s-2004-818524 CrossRefPubMed
7.
go back to reference Gibson AAM, Hendrick EB, Conen PE (1966) Intra-cerebral schwannoma: report of a case. J Neurosurg 24:552–557CrossRefPubMed Gibson AAM, Hendrick EB, Conen PE (1966) Intra-cerebral schwannoma: report of a case. J Neurosurg 24:552–557CrossRefPubMed
9.
go back to reference Guenot M, Bataille B, Wager M (1994) Neurochirurgie 40:263–266 Intra-sellar neurinoma: Apropos of the case and review of the literature. FrenchPubMed Guenot M, Bataille B, Wager M (1994) Neurochirurgie 40:263–266 Intra-sellar neurinoma: Apropos of the case and review of the literature. FrenchPubMed
10.
12.
go back to reference Kontogeorgos G, Sano T, Scheithauer BW, Horvath E (2004) Growth hormone producing adenomas. In: DeLellis RA, Heitz P, Lloyd RV, Eng C (eds) WHO classification of tumours: pathology and genetics of endocrine organs. IARC, Lyon, France, pp 164–166 Kontogeorgos G, Sano T, Scheithauer BW, Horvath E (2004) Growth hormone producing adenomas. In: DeLellis RA, Heitz P, Lloyd RV, Eng C (eds) WHO classification of tumours: pathology and genetics of endocrine organs. IARC, Lyon, France, pp 164–166
17.
go back to reference Penfield W (1958) Intracerebral vascular nerves. Arch Neurol Psychiatry 21:92–94 Penfield W (1958) Intracerebral vascular nerves. Arch Neurol Psychiatry 21:92–94
20.
go back to reference Thapar K, Kovacs K (1998) Neoplasms of the sellar region. In: Bigner DD, McLendon RE, Bruner JM (eds) Russell & Rubinstein’s pathology of tumours of the central nervous system, ed 6. vol 2. Edward Arnold, London, pp 561–677 Thapar K, Kovacs K (1998) Neoplasms of the sellar region. In: Bigner DD, McLendon RE, Bruner JM (eds) Russell & Rubinstein’s pathology of tumours of the central nervous system, ed 6. vol 2. Edward Arnold, London, pp 561–677
21.
go back to reference Ulrich H, Tien RD (1998) Tumours of the cranial, spinal and peripheral nerve sheaths. In: Bigner DD, McLendon RE, Bruner JM (eds) Russell and Rubinstein’s pathology of tumours of the central nervous system, ed 6. vol 2. Edward Arnold, London, pp 141–193 Ulrich H, Tien RD (1998) Tumours of the cranial, spinal and peripheral nerve sheaths. In: Bigner DD, McLendon RE, Bruner JM (eds) Russell and Rubinstein’s pathology of tumours of the central nervous system, ed 6. vol 2. Edward Arnold, London, pp 141–193
22.
go back to reference Whee SM, Lee JI, Kim JH (2002) Intra-sellar schwannoma mimicking pituitary adenoma: a case report. J Korean Med Sci 17:147–150PubMed Whee SM, Lee JI, Kim JH (2002) Intra-sellar schwannoma mimicking pituitary adenoma: a case report. J Korean Med Sci 17:147–150PubMed
24.
go back to reference Woodruff JM, Kourea HO, Louis DN, Scheithaurer BWK (2000) Schwannoma. In: Kleihues P, Cavanee WK (eds) WHO classification of tumours: pathology and genetics of endocrine organs. IARC, Lyon, France, pp 14–19 Woodruff JM, Kourea HO, Louis DN, Scheithaurer BWK (2000) Schwannoma. In: Kleihues P, Cavanee WK (eds) WHO classification of tumours: pathology and genetics of endocrine organs. IARC, Lyon, France, pp 14–19
Metadata
Title
Intra-sellar schwannoma co-existing with GH-secreting pituitary adenoma
Authors
Maria Koutourousiou
Andreas Seretis
George Kontogeorgos
Publication date
01-12-2009
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 12/2009
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-009-0304-7

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