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CardioVascular and Interventional Radiology

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01-08-2013 | Commentary

Intra-arterial Stroke Therapy: Patient Safety Considerations

Authors: Michael J. Lee, Jim A. Reekers, D. Vorwerk

Published in: CardioVascular and Interventional Radiology | Issue 4/2013

Excerpt

Stroke is one of the leading causes of adult disability and mortality worldwide, and approximately 80 % of all strokes are due to ischemia [1, 2]. Acute ischemic stroke (AIS) is now considered a medical emergency that demands prompt intervention to prevent disability and death. Intravenous thrombolysis with recombinant tissue-plasminogen activator (rtPA) during the first hours after the onset of symptoms is now the first-line treatment for ischemic stroke [3‐5]. However, IV thrombolysis is not as affective when there is occlusion of a relatively large artery. Alternative treatments such as intra-arterial thrombolysis or mechanical thrombectomy have been studied, with encouraging results [6‐14]. Randomized controlled trials have been published detailing the results of intra-arterial thrombolysis [15‐18] but as of yet, there is no level 1 evidence regarding the efficacy of mechanical or stent-assisted thrombectomy. …

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Title: Intra-arterial Stroke Therapy: Patient Safety Considerations
Authors: Michael J. Lee
Jim A. Reekers
D. Vorwerk
Publication date: 01-08-2013
Publisher: Springer New York
Published in: CardioVascular and Interventional Radiology / Issue 4/2013
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-013-0651-x

At a glance: The STEP trials

Springer Medicine

Intra-arterial Stroke Therapy: Patient Safety Considerations

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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