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Journal of Orthopaedic Science
Published in: Journal of Orthopaedic Science 5/2006

Open Access 01-09-2006 | Instructional lecture

Intervertebral disc degeneration: biological and biomechanical factors

Authors: Howard S. An, Koichi Masuda, Nozomu Inoue

Published in: Journal of Orthopaedic Science | Issue 5/2006

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Excerpt

There has been significant progress over the past two decades in the surgical treatment of spinal disorders, including advances in spinal instrumentation, minimally invasive spine surgery, biomaterials, and artificial disc replacement. Although improvements in surgical treatments are on track, basic science research on the pathogenesis of intervertebral disc (IVD) degeneration and the mechanism of pain is nascent. A better understanding of the pathogenesis of IVD degeneration will culminate in greater advances in treatment and improve patient selection and indications for emerging techniques and procedures. In this article, we review the relevant literature on biological and biomechanical research, including our own recent publications. …
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Metadata
Title
Intervertebral disc degeneration: biological and biomechanical factors
Authors
Howard S. An
Koichi Masuda
Nozomu Inoue
Publication date
01-09-2006
Publisher
Springer-Verlag
Published in
Journal of Orthopaedic Science / Issue 5/2006
Print ISSN: 0949-2658
Electronic ISSN: 1436-2023
DOI
https://doi.org/10.1007/s00776-006-1055-4

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