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Published in: World Journal of Surgery 6/2006

01-06-2006

Intervention-free Interval following Strictureplasty for Crohn’s Disease

Authors: Pratik Roy, Devinder Kumar

Published in: World Journal of Surgery | Issue 6/2006

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Abstract

Introduction

Strictureplasty is now well established as a bowel-sparing alternative for surgical treatment of complicated Crohn’s disease. Limited resection is still preferred in patients with uncomplicated disease, as subsequent reoperation rates are low.

Methods

A retrospective review of 26 patients who underwent surgery for small bowel Crohn’s disease between 1996 and 2004 was undertaken. A total of 96 small bowel strictureplasties had been performed; 19 patients had strictureplasties performed in isolation, and the remaining 7 patients underwent strictureplasty with concomitant limited resection.

Results

There was no operative mortality. The median follow-up was 41 months. Four patients developed complications that required further surgery. At 41 months, 73.3% of patients undergoing strictureplasty alone and 79.7% undergoing strictureplasty with concomitant resection were intervention-free. If followed up to 70 months or more, the same proportion of patients would remain intervention-free. Four patients developed further recrudescent disease and required surgery: strictureplasty, limited resection, or both. Of these patients, 25% were intervention-free at 41 months.

Conclusions

Our results show that strictureplasty alone or with concomitant resection can confer intervention-free periods of 41 months or more in 73.3% of patients, suggesting that strictureplasty can be utilized as an alternative to limited resection in uncomplicated Crohn’s disease.
Literature
1.
go back to reference Alexander-Williams J, Kumar D. Strictureplasty. Crohn’s Disease and Ulcerative Colitis: Surgical Management. London, Springer, 1993;89–101 Alexander-Williams J, Kumar D. Strictureplasty. Crohn’s Disease and Ulcerative Colitis: Surgical Management. London, Springer, 1993;89–101
3.
go back to reference Katariya RN, Sood S, Rao PG, et al. Stricture-plasty for tubercular strictures of the gastro-intestinal tract. Br J Surg 1977;64:496–498PubMed Katariya RN, Sood S, Rao PG, et al. Stricture-plasty for tubercular strictures of the gastro-intestinal tract. Br J Surg 1977;64:496–498PubMed
4.
go back to reference Lee EC, Papaioannou N. Minimal surgery for chronic obstruction in patients with extensive or universal Crohn’s disease. Ann R Coll Surg Engl 1982;64:229–233PubMed Lee EC, Papaioannou N. Minimal surgery for chronic obstruction in patients with extensive or universal Crohn’s disease. Ann R Coll Surg Engl 1982;64:229–233PubMed
5.
go back to reference Alexander-Williams J, Fornaro M. [“Strictureplasty” in Crohn’s disease]. Chirurg 1982;53:799–801PubMed Alexander-Williams J, Fornaro M. [“Strictureplasty” in Crohn’s disease]. Chirurg 1982;53:799–801PubMed
6.
go back to reference Yamamoto T, Bain IM, Connolly AB, et al. Outcome of strictureplasty for duodenal Crohn’s disease. Br J Surg 1999;86:259–262PubMedCrossRef Yamamoto T, Bain IM, Connolly AB, et al. Outcome of strictureplasty for duodenal Crohn’s disease. Br J Surg 1999;86:259–262PubMedCrossRef
7.
go back to reference Cristaldi M, Sampietro GM, Danelli PG, et al. Long-term results and multivariate analysis of prognostic factors in 138 consecutive patients operated on for Crohn’s disease using “bowel-sparing” techniques. Am J Surg 2000;179:266–270PubMedCrossRef Cristaldi M, Sampietro GM, Danelli PG, et al. Long-term results and multivariate analysis of prognostic factors in 138 consecutive patients operated on for Crohn’s disease using “bowel-sparing” techniques. Am J Surg 2000;179:266–270PubMedCrossRef
8.
go back to reference Dietz DW, Laureti S, Strong SA, et al. Safety and long term efficacy of strictureplasty in 314 patients with obstructing small bowel Crohn’s disease. J Am Coll Surg 2001;192:330–337PubMedCrossRef Dietz DW, Laureti S, Strong SA, et al. Safety and long term efficacy of strictureplasty in 314 patients with obstructing small bowel Crohn’s disease. J Am Coll Surg 2001;192:330–337PubMedCrossRef
9.
go back to reference Fazio VW, Tjandra JJ. Strictureplasty for Crohn’s disease with multiple long strictures. Dis Colon Rectum 1993;36:71–72PubMedCrossRef Fazio VW, Tjandra JJ. Strictureplasty for Crohn’s disease with multiple long strictures. Dis Colon Rectum 1993;36:71–72PubMedCrossRef
10.
go back to reference Hurst RD, Michelassi F. Strictureplasty for Crohn’s disease: techniques and long-term results. World J Surg 1998;22:359–363PubMedCrossRef Hurst RD, Michelassi F. Strictureplasty for Crohn’s disease: techniques and long-term results. World J Surg 1998;22:359–363PubMedCrossRef
11.
go back to reference Stebbing JF, Jewell DP, Kettlewell MG, et al. Recurrence and reoperation after strictureplasty for obstructive Crohn’s disease: long-term results [corrected]. Br J Surg 1995;82:1471–1474PubMed Stebbing JF, Jewell DP, Kettlewell MG, et al. Recurrence and reoperation after strictureplasty for obstructive Crohn’s disease: long-term results [corrected]. Br J Surg 1995;82:1471–1474PubMed
12.
go back to reference Tjandra JJ, Fazio VW. Strictureplasty for ileocolic anastomotic strictures in Crohn’s disease. Dis Colon Rectum 1993;36:1099–1103PubMedCrossRef Tjandra JJ, Fazio VW. Strictureplasty for ileocolic anastomotic strictures in Crohn’s disease. Dis Colon Rectum 1993;36:1099–1103PubMedCrossRef
13.
go back to reference Agwunobi AO, Carlson GL, Anderson ID, et al. Mechanisms of intestinal failure in Crohn’s disease. Dis Colon Rectum 2001;44:1834–1837PubMedCrossRef Agwunobi AO, Carlson GL, Anderson ID, et al. Mechanisms of intestinal failure in Crohn’s disease. Dis Colon Rectum 2001;44:1834–1837PubMedCrossRef
14.
go back to reference Dunne WT, Cooke WT, Allan RN. Enzymatic and morphometric evidence for Crohn’s disease as a diffuse lesion of the gastrointestinal tract. Gut 1977;18:290–294PubMed Dunne WT, Cooke WT, Allan RN. Enzymatic and morphometric evidence for Crohn’s disease as a diffuse lesion of the gastrointestinal tract. Gut 1977;18:290–294PubMed
15.
go back to reference Wakefield AJ, Sawyerr AM, Dhillon AP, et al. Pathogenesis of Crohn’s disease: multifocal gastrointestinal infarction. Lancet 1989;2:1057–1062PubMedCrossRef Wakefield AJ, Sawyerr AM, Dhillon AP, et al. Pathogenesis of Crohn’s disease: multifocal gastrointestinal infarction. Lancet 1989;2:1057–1062PubMedCrossRef
16.
go back to reference Kim NK, Senagore AJ, Luchtefeld MA, et al. Long-term outcome after ileocaecal resection for Crohn’s disease. Am Surg 1997;63:627–633PubMed Kim NK, Senagore AJ, Luchtefeld MA, et al. Long-term outcome after ileocaecal resection for Crohn’s disease. Am Surg 1997;63:627–633PubMed
17.
go back to reference Lauschke H, Kaminski M, Wiedwald C, et al. [Long-term results after surgical therapy of Crohn’s disease.] Zentralbl Chir 2002;127:706–711PubMedCrossRef Lauschke H, Kaminski M, Wiedwald C, et al. [Long-term results after surgical therapy of Crohn’s disease.] Zentralbl Chir 2002;127:706–711PubMedCrossRef
18.
go back to reference Kaplan EM, Meier P. Nonparametric observation from incomplete observations. J Am Stat Assoc 1958;53:457–481CrossRef Kaplan EM, Meier P. Nonparametric observation from incomplete observations. J Am Stat Assoc 1958;53:457–481CrossRef
19.
go back to reference Borley NR, Mortensen NJ, Chaudry MA, et al. Recurrence after abdominal surgery for Crohn’s disease: relationship to disease site and surgical procedure. Dis Colon Rectum 2002;45:377–383PubMedCrossRef Borley NR, Mortensen NJ, Chaudry MA, et al. Recurrence after abdominal surgery for Crohn’s disease: relationship to disease site and surgical procedure. Dis Colon Rectum 2002;45:377–383PubMedCrossRef
20.
go back to reference Parente F, Sampietro GM, Molteni M, et al. Behaviour of the bowel wall during the first year after surgery is a strong predictor of symptomatic recurrence of Crohn’s disease: a prospective study. Aliment Pharmacol Ther 2004;20:959–968PubMedCrossRef Parente F, Sampietro GM, Molteni M, et al. Behaviour of the bowel wall during the first year after surgery is a strong predictor of symptomatic recurrence of Crohn’s disease: a prospective study. Aliment Pharmacol Ther 2004;20:959–968PubMedCrossRef
21.
go back to reference Laurent S, Detry O, Detroz B, et al. Strictureplasty in Crohn’s disease: short- and long-term follow-up. Acta Chir Belg 2002;102:253–255PubMed Laurent S, Detry O, Detroz B, et al. Strictureplasty in Crohn’s disease: short- and long-term follow-up. Acta Chir Belg 2002;102:253–255PubMed
22.
go back to reference Serra J, Cohen Z, McLeod RS. Natural history of strictureplasty in Crohn’s disease: 9-year experience. Can J Surg 1995;38:481–485PubMed Serra J, Cohen Z, McLeod RS. Natural history of strictureplasty in Crohn’s disease: 9-year experience. Can J Surg 1995;38:481–485PubMed
23.
go back to reference Spencer MP, Nelson H, Wolff BG, et al. Strictureplasty for obstructive Crohn’s disease: the Mayo experience. Mayo Clin Proc 1994;69:33–36PubMed Spencer MP, Nelson H, Wolff BG, et al. Strictureplasty for obstructive Crohn’s disease: the Mayo experience. Mayo Clin Proc 1994;69:33–36PubMed
24.
go back to reference Tichansky D, Cagir B, Yoo E, et al. Strictureplasty for Crohn’s disease: meta-analysis. Dis Colon Rectum 2000;43:911–919PubMedCrossRef Tichansky D, Cagir B, Yoo E, et al. Strictureplasty for Crohn’s disease: meta-analysis. Dis Colon Rectum 2000;43:911–919PubMedCrossRef
25.
go back to reference Present DH, Korelitz BI, Wisch N, et al. Treatment of Crohn’s disease with 6-mercaptopurine: a long-term, randomized, double-blind study. N Engl J Med 1980;302:981–987PubMedCrossRef Present DH, Korelitz BI, Wisch N, et al. Treatment of Crohn’s disease with 6-mercaptopurine: a long-term, randomized, double-blind study. N Engl J Med 1980;302:981–987PubMedCrossRef
26.
go back to reference Michelassi F. Side-to-side isoperistaltic strictureplasty for multiple Crohn’s strictures. Dis Colon Rectum 1996;39:345–349PubMedCrossRef Michelassi F. Side-to-side isoperistaltic strictureplasty for multiple Crohn’s strictures. Dis Colon Rectum 1996;39:345–349PubMedCrossRef
27.
go back to reference Michelassi F, Hurst RD, Melis M, et al. Side-to-side isoperistaltic strictureplasty in extensive Crohn’s disease: a prospective longitudinal study. Ann Surg 2000;232:401–408PubMedCrossRef Michelassi F, Hurst RD, Melis M, et al. Side-to-side isoperistaltic strictureplasty in extensive Crohn’s disease: a prospective longitudinal study. Ann Surg 2000;232:401–408PubMedCrossRef
28.
go back to reference Poggioli G, Laureti S, Pierangeli F, et al. A new model of strictureplasty for multiple and long stenoses in Crohn’s ileitis: side-to-side diseased to disease-free anastomosis. Dis Colon Rectum 2003;46:127–130PubMedCrossRef Poggioli G, Laureti S, Pierangeli F, et al. A new model of strictureplasty for multiple and long stenoses in Crohn’s ileitis: side-to-side diseased to disease-free anastomosis. Dis Colon Rectum 2003;46:127–130PubMedCrossRef
Metadata
Title
Intervention-free Interval following Strictureplasty for Crohn’s Disease
Authors
Pratik Roy
Devinder Kumar
Publication date
01-06-2006
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 6/2006
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-005-0284-6

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