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Open Access 01-12-2015 | Poster presentation

Interim sample size re-estimation in the IIVOP trial

Authors: Sarah Dawson, Mike Lee, Simon Bond

Published in: Trials | Special Issue 2/2015

Excerpt

The IIVOP trial is a cross-over trial which examines the effect of the drug ivabridine in reducing pain in an enriched healthy volunteer pain model. The trial was designed based on very limited information, and as such an interim analysis was built into the design to allow the re-estimation of the sample size requirements based on updated trial parameters. …

Title: Interim sample size re-estimation in the IIVOP trial
Authors: Sarah Dawson
Mike Lee
Simon Bond
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Trials / Issue Special Issue 2/2015
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/1745-6215-16-S2-P128

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Interim sample size re-estimation in the IIVOP trial

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