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Published in: Critical Care 1/2011

Open Access 01-02-2011 | Poster presentation

Interactions of endotoxin, albumin function, albumin binding capacity and oxidative stress in brain-dead organ donors

Authors: V Stadlbauer, B Leber, P Stiegler, S Stanzer, U Mayrhauser, S Köstenbauer, M Sereinigg, A Puntschart, T Stojakovic, K Tscheliessnigg, K Oettl

Published in: Critical Care | Special Issue 1/2011

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Excerpt

Albumin binds and detoxifies endotoxin in healthy people. Oxidative stress leads to protein oxidation and thus to impaired binding properties of albumin. This, in combination with increased gut permeability, leads to appearance of endotoxin in the systemic circulation and further to impaired organ function. We hypothesise that these processes occur in serum of brain-dead organ donors. …
Metadata
Title
Interactions of endotoxin, albumin function, albumin binding capacity and oxidative stress in brain-dead organ donors
Authors
V Stadlbauer
B Leber
P Stiegler
S Stanzer
U Mayrhauser
S Köstenbauer
M Sereinigg
A Puntschart
T Stojakovic
K Tscheliessnigg
K Oettl
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9944

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