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01-10-2017 | Editorial

Intensive care medicine in 2050: precision medicine

Author: Hector R. Wong

Published in: Intensive Care Medicine | Issue 10/2017

Excerpt

By 2050, intensive care medicine will evolve from reliance on treatment protocols, guidelines, consensus definitions, and organ support to regularly applying the principles of precision medicine. Precision medicine entails the customization of therapies based on unique features of an individual patient or of patient subtypes. At a fundamental level, we already practice precision medicine. For example, among patients with cardiovascular shock, we select different pharmacologic agents on the basis of the etiology of shock. However, the hope is that the field can evolve toward a more granular form of precision medicine, wherein we directly address the unique molecular and biological features of an individual patient. For example, the rapidly evolving discipline of pharmacogenomics provides an opportunity to tailor drug selection and dosing based on genetic variants modifying drug response and metabolism [1]. …

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Title: Intensive care medicine in 2050: precision medicine
Author: Hector R. Wong
Publication date: 01-10-2017
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 10/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4727-y

At a glance: The STEP trials

Springer Medicine

Intensive care medicine in 2050: precision medicine

Excerpt

At a glance: The STEP trials

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Excerpt

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