Skip to main content
Top
Published in: BMC Ophthalmology 1/2023

Open Access 01-12-2023 | Intense Pulsed Light | Research

Intense pulsed-light treatment improves objective optical quality in patients with meibomian gland dysfunction

Authors: Woong-Joo Whang, Jeongseop Yun, Kyungmin Koh

Published in: BMC Ophthalmology | Issue 1/2023

Login to get access

Abstract

Background

To evaluate changes in objective optical quality following intense pulsed light (IPL) treatment combined with meibomian gland (MG) expression (MGX) in patients with MG dysfunction (MGD).

Methods

This retrospective cross-sectional study included MGD-related dry eye disease (DED) patients who received IPL treatment between March and December 2021 at Kim’s Eye Hospital, Seoul, Republic of Korea. Each patient underwent four sessions of IPL treatment using Lumenis M22 (Lumenis Ltd., Yokneam, Israel) and MGX at three-week intervals.

Results

This study included 90 eyes from 45 patients with MGD. The mean age was 52.3 ± 16.1 years (range, 20–75 years), and 53.3% (24/45) of patients were female. Compared with the baseline, all clinical symptoms and signs significantly improved after IPL treatment combined with MGX. All optical quality parameters obtained with an optical quality analysis system (OQAS: Visiometrics, Castelldefels, Spain) have improved significantly over the baseline (p < 0.001).

Conclusions

In patients with MGD, IPL treatment combined with MGX improved the objective optical quality and clinical signs and symptoms of DED.
Appendix
Available only for authorised users
Literature
1.
go back to reference Lemp MA, Crews LA, Bron AJ, Foulks GN, Sullivan BD. Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study. Cornea. 2012;31(5):472–8.PubMedCrossRef Lemp MA, Crews LA, Bron AJ, Foulks GN, Sullivan BD. Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study. Cornea. 2012;31(5):472–8.PubMedCrossRef
2.
go back to reference Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, Na KS, Schaumberg D, Uchino M, Vehof J, et al. TFOS DEWS II Epidemiology Report. Ocul Surf. 2017;15(3):334–65.CrossRefPubMed Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, Na KS, Schaumberg D, Uchino M, Vehof J, et al. TFOS DEWS II Epidemiology Report. Ocul Surf. 2017;15(3):334–65.CrossRefPubMed
3.
go back to reference Donthineni PR, Kammari P, Shanbhag SS, Singh V, Das AV, Basu S. Incidence, demographics, types and risk factors of dry eye disease in India: electronic medical records driven big data analytics report I. Ocul Surf. 2019;17(2):250–6.PubMedCrossRef Donthineni PR, Kammari P, Shanbhag SS, Singh V, Das AV, Basu S. Incidence, demographics, types and risk factors of dry eye disease in India: electronic medical records driven big data analytics report I. Ocul Surf. 2019;17(2):250–6.PubMedCrossRef
4.
go back to reference Tutt R, Bradley A, Begley C, Thibos LN. Optical and visual impact of tear break-up in human eyes. Investig Ophthalmol Vis Sci. 2000;41(13):4117–23. Tutt R, Bradley A, Begley C, Thibos LN. Optical and visual impact of tear break-up in human eyes. Investig Ophthalmol Vis Sci. 2000;41(13):4117–23.
5.
go back to reference Koh S, Tung CI, Inoue Y, Jhanji V. Effects of tear film dynamics on quality of vision. Br J Ophthalmol. 2018;102(12):1615–20.PubMedCrossRef Koh S, Tung CI, Inoue Y, Jhanji V. Effects of tear film dynamics on quality of vision. Br J Ophthalmol. 2018;102(12):1615–20.PubMedCrossRef
6.
go back to reference Yokoi N, Uchino M, Uchino Y, Dogru M, Kawashima M, Komuro A, Sonomura Y, Kato H, Tsubota K, Kinoshita S. Importance of tear film instability in dry eye disease in office workers using visual display terminals: the Osaka study. Am J Ophthalmol. 2015;159(4):748–54.PubMedCrossRef Yokoi N, Uchino M, Uchino Y, Dogru M, Kawashima M, Komuro A, Sonomura Y, Kato H, Tsubota K, Kinoshita S. Importance of tear film instability in dry eye disease in office workers using visual display terminals: the Osaka study. Am J Ophthalmol. 2015;159(4):748–54.PubMedCrossRef
7.
go back to reference Karaca EE, Evren Kemer Ö, Özek D. Intense regulated pulse light for the meibomian gland dysfunction. Eur J Ophthalmol. 2020;30(2):289–92.PubMedCrossRef Karaca EE, Evren Kemer Ö, Özek D. Intense regulated pulse light for the meibomian gland dysfunction. Eur J Ophthalmol. 2020;30(2):289–92.PubMedCrossRef
8.
go back to reference Montés-Micó R. Role of the tear film in the optical quality of the human eye. J Cataract Refract Surg. 2007;33(9):1631–5.PubMedCrossRef Montés-Micó R. Role of the tear film in the optical quality of the human eye. J Cataract Refract Surg. 2007;33(9):1631–5.PubMedCrossRef
9.
go back to reference Montés-Micó R, Cáliz A, Alió JL. Changes in ocular aberrations after instillation of artificial tears in dry-eye patients. J Cataract Refract Surg. 2004;30(8):1649–52.PubMedCrossRef Montés-Micó R, Cáliz A, Alió JL. Changes in ocular aberrations after instillation of artificial tears in dry-eye patients. J Cataract Refract Surg. 2004;30(8):1649–52.PubMedCrossRef
10.
go back to reference Huang FC, Tseng SH, Shih MH, Chen FK. Effect of artificial tears on corneal surface regularity, contrast sensitivity, and glare disability in dry eyes. Ophthalmology. 2002;109(10):1934–40.PubMedCrossRef Huang FC, Tseng SH, Shih MH, Chen FK. Effect of artificial tears on corneal surface regularity, contrast sensitivity, and glare disability in dry eyes. Ophthalmology. 2002;109(10):1934–40.PubMedCrossRef
11.
go back to reference Montés-Micó R, Cáliz A, Alió JL. Wavefront analysis of higher order aberrations in dry eye patients. J refractive Surg (Thorofare NJ: 1995). 2004;20(3):243–7.CrossRef Montés-Micó R, Cáliz A, Alió JL. Wavefront analysis of higher order aberrations in dry eye patients. J refractive Surg (Thorofare NJ: 1995). 2004;20(3):243–7.CrossRef
12.
go back to reference Chung HS, Han YE, Lee H, Kim JY, Tchah H. Intense pulsed light treatment of the upper and lower eyelids in patients with moderate-to-severe meibomian gland dysfunction. Int Ophthalmol 2022. Chung HS, Han YE, Lee H, Kim JY, Tchah H. Intense pulsed light treatment of the upper and lower eyelids in patients with moderate-to-severe meibomian gland dysfunction. Int Ophthalmol 2022.
13.
go back to reference Qin G, Chen J, Li L, Xia Y, Zhang Q, Wu Y, Yang L, Moutari S, Moore JE, Xu L, et al. Managing severe evaporative Dry Eye with intense pulsed light therapy. Ophthalmology and therapy; 2023. Qin G, Chen J, Li L, Xia Y, Zhang Q, Wu Y, Yang L, Moutari S, Moore JE, Xu L, et al. Managing severe evaporative Dry Eye with intense pulsed light therapy. Ophthalmology and therapy; 2023.
14.
go back to reference Lee SH, Kim M, Lee WJ, Chun YS, Kim KW. Different number of Sessions of intense pulsed light and meibomian gland expression combination therapy for Meibomian Gland Dysfunction. Korean J ophthalmology: KJO. 2022;36(6):527–42.PubMedPubMedCentralCrossRef Lee SH, Kim M, Lee WJ, Chun YS, Kim KW. Different number of Sessions of intense pulsed light and meibomian gland expression combination therapy for Meibomian Gland Dysfunction. Korean J ophthalmology: KJO. 2022;36(6):527–42.PubMedPubMedCentralCrossRef
15.
go back to reference Chung HS, Han YE, Lee H, Kim JY, Tchah H. Intense pulsed light treatment of the upper and lower eyelids in patients with moderate-to-severe meibomian gland dysfunction. Int Ophthalmol. 2023;43(1):73–82.PubMedCrossRef Chung HS, Han YE, Lee H, Kim JY, Tchah H. Intense pulsed light treatment of the upper and lower eyelids in patients with moderate-to-severe meibomian gland dysfunction. Int Ophthalmol. 2023;43(1):73–82.PubMedCrossRef
16.
go back to reference Tang Y, Liu R, Tu P, Song W, Qiao J, Yan X, Rong B. A retrospective study of treatment outcomes and prognostic factors of intense Pulsed Light Therapy Combined with Meibomian Gland expression in patients with Meibomian Gland Dysfunction. Eye Contact Lens. 2021;47(1):38–44.PubMedCrossRef Tang Y, Liu R, Tu P, Song W, Qiao J, Yan X, Rong B. A retrospective study of treatment outcomes and prognostic factors of intense Pulsed Light Therapy Combined with Meibomian Gland expression in patients with Meibomian Gland Dysfunction. Eye Contact Lens. 2021;47(1):38–44.PubMedCrossRef
17.
go back to reference Toyos R, Toyos M, Willcox J, Mulliniks H, Hoover J. Evaluation of the safety and efficacy of intense pulsed light treatment with Meibomian Gland expression of the Upper Eyelids for Dry Eye Disease. Photobiomodulation Photomed laser Surg. 2019;37(9):527–31.CrossRef Toyos R, Toyos M, Willcox J, Mulliniks H, Hoover J. Evaluation of the safety and efficacy of intense pulsed light treatment with Meibomian Gland expression of the Upper Eyelids for Dry Eye Disease. Photobiomodulation Photomed laser Surg. 2019;37(9):527–31.CrossRef
18.
go back to reference Shin KY, Lim DH, Moon CH, Kim BJ, Chung TY. Intense pulsed light plus meibomian gland expression versus intense pulsed light alone for meibomian gland dysfunction: a randomized crossover study. PLoS ONE. 2021;16(3):e0246245.PubMedPubMedCentralCrossRef Shin KY, Lim DH, Moon CH, Kim BJ, Chung TY. Intense pulsed light plus meibomian gland expression versus intense pulsed light alone for meibomian gland dysfunction: a randomized crossover study. PLoS ONE. 2021;16(3):e0246245.PubMedPubMedCentralCrossRef
19.
go back to reference Tashbayev B, Yazdani M, Arita R, Fineide F, Utheim TP. Intense pulsed light treatment in meibomian gland dysfunction: a concise review. Ocul Surf. 2020;18(4):583–94.PubMedCrossRef Tashbayev B, Yazdani M, Arita R, Fineide F, Utheim TP. Intense pulsed light treatment in meibomian gland dysfunction: a concise review. Ocul Surf. 2020;18(4):583–94.PubMedCrossRef
20.
go back to reference Fan Q, Pazo EE, You Y, Zhang C, Zhang C, Xu L, He W. Subjective quality of Vision in Evaporative Dry Eye Patients after intense pulsed light. Photobiomodulation Photomed laser Surg. 2020;38(7):444–51.CrossRef Fan Q, Pazo EE, You Y, Zhang C, Zhang C, Xu L, He W. Subjective quality of Vision in Evaporative Dry Eye Patients after intense pulsed light. Photobiomodulation Photomed laser Surg. 2020;38(7):444–51.CrossRef
21.
go back to reference Yang L, Pazo EE, Qin G, Zhang Q, Wu Y, Song Y, Zhang H, Lin T, Xu L, Moore JE, et al. Effect of intense pulsed light on anterior corneal aberrations and quality of vision in patients with evaporative Dry Eye. Photobiomodulation Photomed laser Surg. 2021;39(3):185–95.CrossRef Yang L, Pazo EE, Qin G, Zhang Q, Wu Y, Song Y, Zhang H, Lin T, Xu L, Moore JE, et al. Effect of intense pulsed light on anterior corneal aberrations and quality of vision in patients with evaporative Dry Eye. Photobiomodulation Photomed laser Surg. 2021;39(3):185–95.CrossRef
22.
go back to reference Ozcura F, Aydin S, Helvaci MR. Ocular surface disease index for the diagnosis of dry eye syndrome. Ocul Immunol Inflamm. 2007;15(5):389–93.PubMedCrossRef Ozcura F, Aydin S, Helvaci MR. Ocular surface disease index for the diagnosis of dry eye syndrome. Ocul Immunol Inflamm. 2007;15(5):389–93.PubMedCrossRef
23.
go back to reference Echieh CI, Etim BA, Echieh CP, Oyeniyi T, Ajewole J. A comparative assessment of dry eye disease among outdoor street sweepers and indoor office cleaners. BMC Ophthalmol. 2021;21(1):265.PubMedPubMedCentralCrossRef Echieh CI, Etim BA, Echieh CP, Oyeniyi T, Ajewole J. A comparative assessment of dry eye disease among outdoor street sweepers and indoor office cleaners. BMC Ophthalmol. 2021;21(1):265.PubMedPubMedCentralCrossRef
24.
go back to reference Park Y, Kim H, Kim S, Cho KJ. Effect of low-level light therapy in patients with dry eye: a prospective, randomized, observer-masked trial. Sci Rep. 2022;12(1):3575.PubMedPubMedCentralCrossRef Park Y, Kim H, Kim S, Cho KJ. Effect of low-level light therapy in patients with dry eye: a prospective, randomized, observer-masked trial. Sci Rep. 2022;12(1):3575.PubMedPubMedCentralCrossRef
25.
go back to reference Jiang X, Lv H, Song H, Zhang M, Liu Y, Hu X, Li X, Wang W. Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction. Journal of ophthalmology 2016, 2016:1910694. Jiang X, Lv H, Song H, Zhang M, Liu Y, Hu X, Li X, Wang W. Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction. Journal of ophthalmology 2016, 2016:1910694.
26.
go back to reference Chen C, Chen D, Chou YY, Long Q. Factors influencing the clinical outcomes of intense pulsed light for meibomian gland dysfunction. Med (Baltim). 2021;100(49):e28166.CrossRef Chen C, Chen D, Chou YY, Long Q. Factors influencing the clinical outcomes of intense pulsed light for meibomian gland dysfunction. Med (Baltim). 2021;100(49):e28166.CrossRef
27.
go back to reference Yu HJ, Kaiser PK, Zamora D, Bocanegra M, Cone C, Brown DM, Sadda SR, Wykoff CC. Visual acuity variability: comparing discrepancies between Snellen and ETDRS measurements among subjects entering prospective trials. Ophthalmol Retina. 2021;5(3):224–33.PubMedCrossRef Yu HJ, Kaiser PK, Zamora D, Bocanegra M, Cone C, Brown DM, Sadda SR, Wykoff CC. Visual acuity variability: comparing discrepancies between Snellen and ETDRS measurements among subjects entering prospective trials. Ophthalmol Retina. 2021;5(3):224–33.PubMedCrossRef
28.
go back to reference Ruan F, Zang Y, Sella R, Lu H, Li S, Yang K, Jin T, Afshari NA, Pan Z, Jie Y. Intense pulsed light therapy with optimal Pulse Technology as an Adjunct Therapy for moderate to severe Blepharitis-Associated Keratoconjunctivitis. J Ophthalmol. 2019;2019:3143469.PubMedPubMedCentralCrossRef Ruan F, Zang Y, Sella R, Lu H, Li S, Yang K, Jin T, Afshari NA, Pan Z, Jie Y. Intense pulsed light therapy with optimal Pulse Technology as an Adjunct Therapy for moderate to severe Blepharitis-Associated Keratoconjunctivitis. J Ophthalmol. 2019;2019:3143469.PubMedPubMedCentralCrossRef
29.
go back to reference Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the ocular surface Disease Index. Archives of ophthalmology (Chicago Ill: 1960). 2000;118(5):615–21.PubMedCrossRef Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the ocular surface Disease Index. Archives of ophthalmology (Chicago Ill: 1960). 2000;118(5):615–21.PubMedCrossRef
30.
go back to reference Asiedu K, Kyei S, Boampong F, Ocansey S. Symptomatic Dry Eye and its Associated factors: a study of University undergraduate students in Ghana. Eye Contact Lens. 2017;43(4):262–6.PubMedCrossRef Asiedu K, Kyei S, Boampong F, Ocansey S. Symptomatic Dry Eye and its Associated factors: a study of University undergraduate students in Ghana. Eye Contact Lens. 2017;43(4):262–6.PubMedCrossRef
31.
go back to reference Lu F, Tao A, Hu Y, Tao W, Lu P. Evaluation of reliability and validity of three common Dry Eye Questionnaires in Chinese. J Ophthalmol. 2018;2018:2401213.PubMedPubMedCentralCrossRef Lu F, Tao A, Hu Y, Tao W, Lu P. Evaluation of reliability and validity of three common Dry Eye Questionnaires in Chinese. J Ophthalmol. 2018;2018:2401213.PubMedPubMedCentralCrossRef
32.
go back to reference Garcin T, Grivet D, Thuret G, Gain P. Using Optical Quality Analysis System for predicting surgical parameters in age-related cataract patients. PLoS ONE. 2020;15(10):e0240350.PubMedPubMedCentralCrossRef Garcin T, Grivet D, Thuret G, Gain P. Using Optical Quality Analysis System for predicting surgical parameters in age-related cataract patients. PLoS ONE. 2020;15(10):e0240350.PubMedPubMedCentralCrossRef
33.
go back to reference Chen T, Yu F, Lin H, Zhao Y, Chang P, Lin L, Chen Q, Zheng Q, Zhao YE, Lu F, et al. Objective and subjective visual quality after implantation of all optic zone diffractive multifocal intraocular lenses: a prospective, case-control observational study. Br J Ophthalmol. 2016;100(11):1530–5.PubMedCrossRef Chen T, Yu F, Lin H, Zhao Y, Chang P, Lin L, Chen Q, Zheng Q, Zhao YE, Lu F, et al. Objective and subjective visual quality after implantation of all optic zone diffractive multifocal intraocular lenses: a prospective, case-control observational study. Br J Ophthalmol. 2016;100(11):1530–5.PubMedCrossRef
34.
go back to reference Shetty R, Deshpande K, Jayadev C, Wadia K, Mehta P, Shroff R, Rao HL. The impact of dysfunctional tear films and optical aberrations on chronic migraine. Eye Vis (Lond). 2017;4:4.PubMedCrossRef Shetty R, Deshpande K, Jayadev C, Wadia K, Mehta P, Shroff R, Rao HL. The impact of dysfunctional tear films and optical aberrations on chronic migraine. Eye Vis (Lond). 2017;4:4.PubMedCrossRef
35.
go back to reference Wei Z, Su Y, Su G, Baudouin C, Labbé A, Liang Q. Effect of artificial tears on dynamic optical quality in patients with dry eye disease. BMC Ophthalmol. 2022;22(1):64.PubMedPubMedCentralCrossRef Wei Z, Su Y, Su G, Baudouin C, Labbé A, Liang Q. Effect of artificial tears on dynamic optical quality in patients with dry eye disease. BMC Ophthalmol. 2022;22(1):64.PubMedPubMedCentralCrossRef
36.
go back to reference Alarcon A, Canovas C, Rosen R, Weeber H, Tsai L, Hileman K, Piers P. Preclinical metrics to predict through-focus visual acuity for pseudophakic patients. Biomedical Opt express. 2016;7(5):1877–88.CrossRef Alarcon A, Canovas C, Rosen R, Weeber H, Tsai L, Hileman K, Piers P. Preclinical metrics to predict through-focus visual acuity for pseudophakic patients. Biomedical Opt express. 2016;7(5):1877–88.CrossRef
37.
go back to reference Pieh S, Fiala W, Malz A, Stork W. In vitro strehl ratios with spherical, aberration-free, average, and customized spherical aberration-correcting intraocular lenses. Investig Ophthalmol Vis Sci. 2009;50(3):1264–70.CrossRef Pieh S, Fiala W, Malz A, Stork W. In vitro strehl ratios with spherical, aberration-free, average, and customized spherical aberration-correcting intraocular lenses. Investig Ophthalmol Vis Sci. 2009;50(3):1264–70.CrossRef
38.
go back to reference Son HS, Tandogan T, Liebing S, Merz P, Choi CY, Khoramnia R, Auffarth GU. In vitro optical quality measurements of three intraocular lens models having identical platform. BMC Ophthalmol. 2017;17(1):108.PubMedPubMedCentralCrossRef Son HS, Tandogan T, Liebing S, Merz P, Choi CY, Khoramnia R, Auffarth GU. In vitro optical quality measurements of three intraocular lens models having identical platform. BMC Ophthalmol. 2017;17(1):108.PubMedPubMedCentralCrossRef
39.
go back to reference Tan QQ, Lin J, Tian J, Liao X, Lan CJ. Objective optical quality in eyes with customized selection of aspheric intraocular lens implantation. BMC Ophthalmol. 2019;19(1):152.PubMedPubMedCentralCrossRef Tan QQ, Lin J, Tian J, Liao X, Lan CJ. Objective optical quality in eyes with customized selection of aspheric intraocular lens implantation. BMC Ophthalmol. 2019;19(1):152.PubMedPubMedCentralCrossRef
40.
go back to reference Kang KH, Song MY, Kim KY, Hwang KY, Kwon YA, Koh K. Visual performance and Optical Quality after Implantation of a New Generation Monofocal intraocular Lens. Korean J ophthalmology: KJO. 2021;35(2):112–9.PubMedPubMedCentralCrossRef Kang KH, Song MY, Kim KY, Hwang KY, Kwon YA, Koh K. Visual performance and Optical Quality after Implantation of a New Generation Monofocal intraocular Lens. Korean J ophthalmology: KJO. 2021;35(2):112–9.PubMedPubMedCentralCrossRef
41.
go back to reference Saad A, Saab M, Gatinel D. Repeatability of measurements with a double-pass system. J Cataract Refract Surg. 2010;36(1):28–33.PubMedCrossRef Saad A, Saab M, Gatinel D. Repeatability of measurements with a double-pass system. J Cataract Refract Surg. 2010;36(1):28–33.PubMedCrossRef
42.
go back to reference Lee J, Hwang G, Ha M, Kim HS, Han K, Na KS. Evaluation of the meibomian glands using the tear interferometer wearing orthokeratology lenses. BMC Ophthalmol. 2022;22(1):133.PubMedPubMedCentralCrossRef Lee J, Hwang G, Ha M, Kim HS, Han K, Na KS. Evaluation of the meibomian glands using the tear interferometer wearing orthokeratology lenses. BMC Ophthalmol. 2022;22(1):133.PubMedPubMedCentralCrossRef
43.
go back to reference Lee JM, Jeon YJ, Kim KY, Hwang KY, Kwon YA, Koh K. Ocular surface analysis: a comparison between the LipiView(®) II and IDRA(®). Eur J Ophthalmol. 2021;31(5):2300–6.PubMedCrossRef Lee JM, Jeon YJ, Kim KY, Hwang KY, Kwon YA, Koh K. Ocular surface analysis: a comparison between the LipiView(®) II and IDRA(®). Eur J Ophthalmol. 2021;31(5):2300–6.PubMedCrossRef
44.
go back to reference Jeon YJ, Song MY, Kim KY, Hwang KY, Kwon YA, Koh K. Relationship between the partial blink rate and ocular surface parameters. Int Ophthalmol. 2021;41(7):2601–8.PubMedPubMedCentralCrossRef Jeon YJ, Song MY, Kim KY, Hwang KY, Kwon YA, Koh K. Relationship between the partial blink rate and ocular surface parameters. Int Ophthalmol. 2021;41(7):2601–8.PubMedPubMedCentralCrossRef
45.
go back to reference Noh SR, Chung JL, Lee JM, Seo KY, Koh K. Meibomian gland atrophy with duration of Sjogren’s syndrome in adult females. Int Ophthalmol. 2022;42(1):191–200.PubMedCrossRef Noh SR, Chung JL, Lee JM, Seo KY, Koh K. Meibomian gland atrophy with duration of Sjogren’s syndrome in adult females. Int Ophthalmol. 2022;42(1):191–200.PubMedCrossRef
46.
go back to reference Park JW, Han J, Choi WK, Kim J, Choi CY. Simple surgical punctal occlusion with high frequency radiowave electrosurgery. BMC Ophthalmol. 2023;23(1):49.PubMedPubMedCentralCrossRef Park JW, Han J, Choi WK, Kim J, Choi CY. Simple surgical punctal occlusion with high frequency radiowave electrosurgery. BMC Ophthalmol. 2023;23(1):49.PubMedPubMedCentralCrossRef
47.
go back to reference Tauber J, Berdy GJ, Wirta DL, Krösser S, Vittitow JL. NOV03 for Dry Eye Disease Associated with Meibomian Gland Dysfunction: results of the Randomized phase 3 GOBI Study. Ophthalmology; 2022. Tauber J, Berdy GJ, Wirta DL, Krösser S, Vittitow JL. NOV03 for Dry Eye Disease Associated with Meibomian Gland Dysfunction: results of the Randomized phase 3 GOBI Study. Ophthalmology; 2022.
48.
go back to reference Ekici E, Çağlar İ, Akgümüş E. The Repeatability, Reproducibility, and Correlation of the Schirmer Test: A Comparison of Open versus Closed Eye. Korean J ophthalmology: KJO 2022. Ekici E, Çağlar İ, Akgümüş E. The Repeatability, Reproducibility, and Correlation of the Schirmer Test: A Comparison of Open versus Closed Eye. Korean J ophthalmology: KJO 2022.
49.
go back to reference Yurttaser Ocak S, Karakus S, Ocak OB, Cakir A, Bolukbasi S, Erden B, Bas E, Elcioglu M. Intense pulse light therapy treatment for refractory dry eye disease due to meibomian gland dysfunction. Int Ophthalmol. 2020;40(5):1135–41.PubMedCrossRef Yurttaser Ocak S, Karakus S, Ocak OB, Cakir A, Bolukbasi S, Erden B, Bas E, Elcioglu M. Intense pulse light therapy treatment for refractory dry eye disease due to meibomian gland dysfunction. Int Ophthalmol. 2020;40(5):1135–41.PubMedCrossRef
50.
go back to reference Kim HM, Eom Y, Song JS. The relationship between morphology and function of the Meibomian Glands. Eye Contact Lens. 2018;44(1):1–5.PubMedCrossRef Kim HM, Eom Y, Song JS. The relationship between morphology and function of the Meibomian Glands. Eye Contact Lens. 2018;44(1):1–5.PubMedCrossRef
51.
go back to reference Lee JS, Jun I, Kim EK, Seo KY, Kim TI. Clinical accuracy of an advanced corneal topographer with Tear-Film analysis in functional and structural evaluation of Dry Eye Disease. Semin Ophthalmol. 2020;35(2):134–40.PubMedCrossRef Lee JS, Jun I, Kim EK, Seo KY, Kim TI. Clinical accuracy of an advanced corneal topographer with Tear-Film analysis in functional and structural evaluation of Dry Eye Disease. Semin Ophthalmol. 2020;35(2):134–40.PubMedCrossRef
52.
go back to reference Eom Y, Na KS, Cho KJ, Hwang HS, Kim SW, Chung TY, Jun RM, Song JS, Kim HS. Distribution and characteristics of Meibomian Gland Dysfunction Subtypes: a Multicenter Study in South Korea. Korean J ophthalmology: KJO. 2019;33(3):205–13.PubMedPubMedCentralCrossRef Eom Y, Na KS, Cho KJ, Hwang HS, Kim SW, Chung TY, Jun RM, Song JS, Kim HS. Distribution and characteristics of Meibomian Gland Dysfunction Subtypes: a Multicenter Study in South Korea. Korean J ophthalmology: KJO. 2019;33(3):205–13.PubMedPubMedCentralCrossRef
53.
go back to reference Li D, Lin SB, Zhang MZ, Cheng B. Preliminary Assessment of intense pulsed light treatment on the Upper Eyelids for Meibomian Gland Dysfunction. Photobiomodulation Photomed laser Surg. 2020;38(4):249–54.CrossRef Li D, Lin SB, Zhang MZ, Cheng B. Preliminary Assessment of intense pulsed light treatment on the Upper Eyelids for Meibomian Gland Dysfunction. Photobiomodulation Photomed laser Surg. 2020;38(4):249–54.CrossRef
54.
go back to reference Kim M, Min J. Effect of Intense Pulsed-Light Treatment Using a Novel Dual-Band Filter in Patients with Meibomian Gland Dysfunction. Journal of clinical medicine 2022, 11(13). Kim M, Min J. Effect of Intense Pulsed-Light Treatment Using a Novel Dual-Band Filter in Patients with Meibomian Gland Dysfunction. Journal of clinical medicine 2022, 11(13).
55.
go back to reference Wu Y, Li J, Hu M, Zhao Y, Lin X, Chen Y, Li L, Zhao YE. Comparison of two intense pulsed light patterns for treating patients with meibomian gland dysfunction. Int Ophthalmol. 2020;40(7):1695–705.PubMedCrossRef Wu Y, Li J, Hu M, Zhao Y, Lin X, Chen Y, Li L, Zhao YE. Comparison of two intense pulsed light patterns for treating patients with meibomian gland dysfunction. Int Ophthalmol. 2020;40(7):1695–705.PubMedCrossRef
56.
go back to reference Min JS, Yoon SH, Kim KY, Jun I, Kim EK, Kim TI, Seo KY. Treatment Effect and Pain during treatment with intense pulsed-light therapy according to the light guide in patients with Meibomian Gland Dysfunction. Cornea. 2022;41(2):177–82.PubMedCrossRef Min JS, Yoon SH, Kim KY, Jun I, Kim EK, Kim TI, Seo KY. Treatment Effect and Pain during treatment with intense pulsed-light therapy according to the light guide in patients with Meibomian Gland Dysfunction. Cornea. 2022;41(2):177–82.PubMedCrossRef
57.
go back to reference Yu AY, Lu T, Pan AP, Lin DR, Xu CC, Huang JH, Bao FJ. Assessment of tear Film Optical Quality Dynamics. Investig Ophthalmol Vis Sci. 2016;57(8):3821–7.CrossRef Yu AY, Lu T, Pan AP, Lin DR, Xu CC, Huang JH, Bao FJ. Assessment of tear Film Optical Quality Dynamics. Investig Ophthalmol Vis Sci. 2016;57(8):3821–7.CrossRef
58.
go back to reference Herbaut A, Liang H, Rabut G, Trinh L, Kessal K, Baudouin C, Labbé A. Impact of Dry Eye Disease on Vision Quality: an Optical Quality Analysis System Study. Translational Vis Sci Technol. 2018;7(4):5.CrossRef Herbaut A, Liang H, Rabut G, Trinh L, Kessal K, Baudouin C, Labbé A. Impact of Dry Eye Disease on Vision Quality: an Optical Quality Analysis System Study. Translational Vis Sci Technol. 2018;7(4):5.CrossRef
59.
go back to reference Koh S, Maeda N, Ikeda C, Asonuma S, Mitamura H, Oie Y, Soma T, Tsujikawa M, Kawasaki S, Nishida K. Ocular forward light scattering and corneal backward light scattering in patients with dry eye. Investig Ophthalmol Vis Sci. 2014;55(10):6601–6.CrossRef Koh S, Maeda N, Ikeda C, Asonuma S, Mitamura H, Oie Y, Soma T, Tsujikawa M, Kawasaki S, Nishida K. Ocular forward light scattering and corneal backward light scattering in patients with dry eye. Investig Ophthalmol Vis Sci. 2014;55(10):6601–6.CrossRef
60.
61.
go back to reference Vigo L, Pellegrini M, Carones F, Scorcia V, Giannaccare G. Outcomes of serial sessions of activa mask combined with intense pulsed light therapy in patients with meibomian gland dysfunction. BMC Ophthalmol. 2022;22(1):313.PubMedPubMedCentralCrossRef Vigo L, Pellegrini M, Carones F, Scorcia V, Giannaccare G. Outcomes of serial sessions of activa mask combined with intense pulsed light therapy in patients with meibomian gland dysfunction. BMC Ophthalmol. 2022;22(1):313.PubMedPubMedCentralCrossRef
62.
go back to reference Jones L, Downie LE, Korb D, Benitez-Del-Castillo JM, Dana R, Deng SX, Dong PN, Geerling G, Hida RY, Liu Y, et al. TFOS DEWS II Management and Therapy Report. Ocul Surf. 2017;15(3):575–628.PubMedCrossRef Jones L, Downie LE, Korb D, Benitez-Del-Castillo JM, Dana R, Deng SX, Dong PN, Geerling G, Hida RY, Liu Y, et al. TFOS DEWS II Management and Therapy Report. Ocul Surf. 2017;15(3):575–628.PubMedCrossRef
63.
go back to reference Arita R, Fukuoka S, Morishige N. Therapeutic efficacy of intense pulsed light in patients with refractory meibomian gland dysfunction. Ocul Surf. 2019;17(1):104–10.PubMedCrossRef Arita R, Fukuoka S, Morishige N. Therapeutic efficacy of intense pulsed light in patients with refractory meibomian gland dysfunction. Ocul Surf. 2019;17(1):104–10.PubMedCrossRef
64.
go back to reference Chung HS, Rhim JW, Park JH. Combination treatment with intense pulsed light, thermal pulsation (LipiFlow), and meibomian gland expression for refractory meibomian gland dysfunction. Int Ophthalmol 2022. Chung HS, Rhim JW, Park JH. Combination treatment with intense pulsed light, thermal pulsation (LipiFlow), and meibomian gland expression for refractory meibomian gland dysfunction. Int Ophthalmol 2022.
65.
go back to reference Toyos R, McGill W, Briscoe D. Intense pulsed light treatment for dry eye disease due to meibomian gland dysfunction; a 3-year retrospective study. Photomed Laser Surg. 2015;33(1):41–6.PubMedPubMedCentralCrossRef Toyos R, McGill W, Briscoe D. Intense pulsed light treatment for dry eye disease due to meibomian gland dysfunction; a 3-year retrospective study. Photomed Laser Surg. 2015;33(1):41–6.PubMedPubMedCentralCrossRef
66.
go back to reference Lee JH, Kim CH, Choe CM, Choi TH. Correlation analysis between ocular surface parameters with subjective Symptom Severity in Dry Eye Disease. Korean J ophthalmology: KJO. 2020;34(3):203–9.PubMedCentralCrossRef Lee JH, Kim CH, Choe CM, Choi TH. Correlation analysis between ocular surface parameters with subjective Symptom Severity in Dry Eye Disease. Korean J ophthalmology: KJO. 2020;34(3):203–9.PubMedCentralCrossRef
67.
go back to reference Walker PM, Lane KJ, Ousler GW 3rd, Abelson MB. Diurnal variation of visual function and the signs and symptoms of dry eye. Cornea. 2010;29(6):607–12.PubMedCrossRef Walker PM, Lane KJ, Ousler GW 3rd, Abelson MB. Diurnal variation of visual function and the signs and symptoms of dry eye. Cornea. 2010;29(6):607–12.PubMedCrossRef
68.
go back to reference Bron AJ, de Paiva CS, Chauhan SK, Bonini S, Gabison EE, Jain S, Knop E, Markoulli M, Ogawa Y, Perez V et al. Corrigendum to “TFOS DEWS II pathophysiology report” [Ocul. Surf. 15 (3) (2017) 438–510]. The ocular surface 2019, 17(4):842. Bron AJ, de Paiva CS, Chauhan SK, Bonini S, Gabison EE, Jain S, Knop E, Markoulli M, Ogawa Y, Perez V et al. Corrigendum to “TFOS DEWS II pathophysiology report” [Ocul. Surf. 15 (3) (2017) 438–510]. The ocular surface 2019, 17(4):842.
69.
go back to reference Hu AL, Qiao LY, Zhang Y, Cai XG, Li L, Wan XH. Reproducibility of optical quality parameters measured at objective and subjective best focuses in a double-pass system. Int J Ophthalmol. 2015;8(5):1043–50.PubMedPubMedCentral Hu AL, Qiao LY, Zhang Y, Cai XG, Li L, Wan XH. Reproducibility of optical quality parameters measured at objective and subjective best focuses in a double-pass system. Int J Ophthalmol. 2015;8(5):1043–50.PubMedPubMedCentral
70.
go back to reference Koh S, Maeda N, Kuroda T, Hori Y, Watanabe H, Fujikado T, Tano Y, Hirohara Y, Mihashi T. Effect of tear film break-up on higher-order aberrations measured with wavefront sensor. Am J Ophthalmol. 2002;134(1):115–7.PubMedCrossRef Koh S, Maeda N, Kuroda T, Hori Y, Watanabe H, Fujikado T, Tano Y, Hirohara Y, Mihashi T. Effect of tear film break-up on higher-order aberrations measured with wavefront sensor. Am J Ophthalmol. 2002;134(1):115–7.PubMedCrossRef
71.
go back to reference Liu H, Thibos L, Begley CG, Bradley A. Measurement of the time course of optical quality and visual deterioration during tear break-up. Investig Ophthalmol Vis Sci. 2010;51(6):3318–26.CrossRef Liu H, Thibos L, Begley CG, Bradley A. Measurement of the time course of optical quality and visual deterioration during tear break-up. Investig Ophthalmol Vis Sci. 2010;51(6):3318–26.CrossRef
72.
go back to reference Goto T, Zheng X, Klyce SD, Kataoka H, Uno T, Yamaguchi M, Karon M, Hirano S, Okamoto S, Ohashi Y. Evaluation of the tear film stability after laser in situ keratomileusis using the tear film stability analysis system. Am J Ophthalmol. 2004;137(1):116–20.PubMedCrossRef Goto T, Zheng X, Klyce SD, Kataoka H, Uno T, Yamaguchi M, Karon M, Hirano S, Okamoto S, Ohashi Y. Evaluation of the tear film stability after laser in situ keratomileusis using the tear film stability analysis system. Am J Ophthalmol. 2004;137(1):116–20.PubMedCrossRef
73.
go back to reference Chu MF, Hui N, Wang CY, Yu L, Ma B, Li Y, Pei C. Early outcomes of vision and objective visual quality analysis after cataract surgery with trifocal intraocular lens implantation. Int J Ophthalmol. 2019;12(10):1575–81.PubMedPubMedCentralCrossRef Chu MF, Hui N, Wang CY, Yu L, Ma B, Li Y, Pei C. Early outcomes of vision and objective visual quality analysis after cataract surgery with trifocal intraocular lens implantation. Int J Ophthalmol. 2019;12(10):1575–81.PubMedPubMedCentralCrossRef
74.
go back to reference Benito A, Pérez GM, Mirabet S, Vilaseca M, Pujol J, Marín JM, Artal P. Objective optical assessment of tear-film quality dynamics in normal and mildly symptomatic dry eyes. J Cataract Refract Surg. 2011;37(8):1481–7.PubMedCrossRef Benito A, Pérez GM, Mirabet S, Vilaseca M, Pujol J, Marín JM, Artal P. Objective optical assessment of tear-film quality dynamics in normal and mildly symptomatic dry eyes. J Cataract Refract Surg. 2011;37(8):1481–7.PubMedCrossRef
Metadata
Title
Intense pulsed-light treatment improves objective optical quality in patients with meibomian gland dysfunction
Authors
Woong-Joo Whang
Jeongseop Yun
Kyungmin Koh
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2023
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-023-02939-9

Other articles of this Issue 1/2023

BMC Ophthalmology 1/2023 Go to the issue