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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2016 | Research article

Insomnia in probable migraine: a population-based study

Authors: Jiyoung Kim, Soo-Jin Cho, Won-Joo Kim, Kwang Ik Yang, Chang-Ho Yun, Min Kyung Chu

Published in: The Journal of Headache and Pain | Issue 1/2015

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Abstract

Background

Insomnia is a common complaint among individuals with migraine. The close association between insomnia and migraine has been reported in clinic-based and population-based studies. Probable migraine (PM) is a migrainous headache which fulfills all but one criterion in the migraine diagnostic criteria. However, an association between insomnia and PM has rarely been reported. This study is to investigate the association between insomnia and PM in comparison with migraine using data from the Korean Headache-Sleep Study.

Methods

The Korean Headache-Sleep Study is a nation-wide cross-sectional survey for all Korean adults aged 19–69 years. The survey was performed via face-to-face interview using a questionnaire on sleep and headache. If an individual’s Insomnia Severity Index score was ≥15.5, she/he was diagnosed as having insomnia.

Results

Of 2695 participants, the prevalence of migraine, PM and insomnia was 5.3, 14.1 and 3.6 %, respectively. The prevalence of insomnia among subjects with PM was not significantly different compared to those with migraine (8.2 % vs. 9.1 %, p = 0.860). However, insomnia prevalence in subjects with PM was significantly higher than in non-headache controls (8.2 % vs. 1.8 %, p < 0.001). Insomnia Severity Index score was significantly higher in subjects with migraine compared to those with PM (6.8 ± 5.8 vs. 5.5 ± 5.8, p = 0.012). Headache frequency and Headache Impact Test-6 score were significantly higher in subjects with migraine and PM with insomnia compared to those without insomnia. Multivariable linear analyses showed that anxiety, depression, headache frequency and headache intensity were independent variables for contributing the ISI score among subjects with PM.

Conclusions

The prevalence of insomnia among subjects with PM was not significantly different compared to those with migraine. Anxiety, depression, headache frequency and headache intensity were related with ISI score in subjects with PM.
Literature
1.
Stovner L, Hagen K, Jensen R, Katsarava Z, Lipton R, Scher A, Steiner T, Zwart JA (2007) The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia 27(3):193–210CrossRefPubMed
2.
Morin CM, LeBlanc M, Daley M, Gregoire JP, Merette C (2006) Epidemiology of insomnia: prevalence, self-help treatments, consultations, and determinants of help-seeking behaviors. Sleep Med 7(2):123–130CrossRefPubMed
3.
Uhlig BL, Engstrom M, Odegard SS, Hagen KK, Sand T (2014) Headache and insomnia in population-based epidemiological studies. Cephalalgia 34(10):745–751CrossRefPubMed
4.
Daley M, Morin CM, LeBlanc M, Gregoire JP, Savard J, Baillargeon L (2009) Insomnia and its relationship to health-care utilization, work absenteeism, productivity and accidents. Sleep Med 10(4):427–438CrossRefPubMed
5.
Bolge SC, Doan JF, Kannan H, Baran RW (2009) Association of insomnia with quality of life, work productivity, and activity impairment. Qual Life Res 18(4):415–422CrossRefPubMed
6.
Leonardi M, Steiner TJ, Scher AT, Lipton RB (2005) The global burden of migraine: measuring disability in headache disorders with WHO’s Classification of Functioning, Disability and Health (ICF). J Headache Pain 6(6):429–440CrossRefPubMedPubMedCentral
7.
Blumenfeld AM, Varon SF, Wilcox TK, Buse DC, Kawata AK, Manack A, Goadsby PJ, Lipton RB (2011) Disability, HRQoL and resource use among chronic and episodic migraineurs: results from the International Burden of Migraine Study (IBMS). Cephalalgia 31(3):301–315CrossRefPubMed
8.
Ødegård SS, Engstrøm M, Sand T, Stovner LJ, Zwart J-A, Hagen K (2010) Associations between sleep disturbance and primary headaches: the third Nord-Trøndelag Health Study. J Headache Pain 11(3):197–206CrossRefPubMedPubMedCentral
9.
Ødegård SS, Sand T, Engstrøm M, Stovner LJ, Zwart JA, Hagen K (2011) The Long‐Term Effect of Insomnia on Primary Headaches: A Prospective Population‐Based Cohort Study (HUNT‐2 and HUNT‐3). Headache: J Head Face Pain 51(4):570–580CrossRef
10.
Ødegård SS, Sand T, Engstrøm M, Zwart J-A, Hagen K (2013) The impact of headache and chronic musculoskeletal complaints on the risk of insomnia: longitudinal data from the Nord-Trøndelag health study. J Headache Pain 14(1):1–10CrossRef
11.
Sutton DA, Moldofsky H, Badley EM (2001) Insomnia and health problems in Canadians. Sleep 24(6):665–670PubMed
12.
Sivertsen B, Krokstad S, Overland S, Mykletun A (2009) The epidemiology of insomnia: associations with physical and mental health. The HUNT-2 study. J Psychosom Res 67(2):109–116CrossRefPubMed
13.
Lucchesi LM, Speciali JG, Santos-Silva R, Taddei JA, Tufik S, Bittencourt LR (2010) Nocturnal awakening with headache and its relationship with sleep disorders in a population-based sample of adult inhabitants of Sao Paulo City, Brazil. Cephalalgia 30(12):1477–1485CrossRefPubMed
14.
Budhiraja R, Roth T, Hudgel DW, Budhiraja P, Drake CL (2011) Prevalence and polysomnographic correlates of insomnia comorbid with medical disorders. Sleep 34(7):859–867CrossRefPubMedPubMedCentral
15.
Huang GB, Yao LT, Hou JX, Zhang ZJ, Xin YT, Wu XY, Lu GY, Chen ZQ, Huang JP (2013) Epidemiology of migraine in the She ethnic minority group in Fujian province, China. Neurol Res 35(7):684–692CrossRefPubMed
16.
Lateef T, Swanson S, Cui L, Nelson K, Nakamura E, Merikangas K (2011) Headaches and sleep problems among adults in the United States: findings from the National Comorbidity Survey-Replication study. Cephalalgia 31(6):648–653CrossRefPubMed
17.
Headache Classification Subcommittee of the International Headache S (2004) The International Classification of Headache Disorders: 2nd edition. Cephalalgia 24(Suppl 1):9–160
18.
Lanteri-Minet M, Valade D, Geraud G, Chautard MH, Lucas C (2005) Migraine and probable migraine--results of FRAMIG 3, a French nationwide survey carried out according to the 2004 IHS classification. Cephalalgia 25(12):1146–1158CrossRefPubMed
19.
Kim BK, Chung YK, Kim JM, Lee KS, Chu MK (2013) Prevalence, clinical characteristics and disability of migraine and probable migraine: a nationwide population-based survey in Korea. Cephalalgia 33(13):1106–1116CrossRefPubMed
20.
Silberstein S, Loder E, Diamond S, Reed ML, Bigal ME, Lipton RB, Group AA (2007) Probable migraine in the United States: results of the American Migraine Prevalence and Prevention (AMPP) study. Cephalalgia 27(3):220–229CrossRefPubMed
21.
Kim BK, Cho SJ, Kim BS, Sohn JH, Kim SK, Cha MJ, Song TJ, Kim JM, Park JW, Chu MK, Park KY, Moon HS (2016) Comprehensive Application of the International Classification of Headache Disorders Third Edition, Beta Version. J Korean Med Sci 31(1):106–113CrossRefPubMed
22.
Cho SJ, Chung YK, Kim JM, Chu MK (2015) Migraine and restless legs syndrome are associated in adults under age fifty but not in adults over fifty: a population-based study. J Headache Pain 16:554CrossRefPubMed
23.
World Medical A (2001) World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects. Bull World Health Organ 79(4):373–374
24.
Stang PE, Osterhaus JT (1993) Impact of migraine in the United States: data from the National Health Interview Survey. Headache 33(1):29–35CrossRefPubMed
25.
Bastien CH, Vallieres A, Morin CM (2001) Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med 2(4):297–307CrossRefPubMed
26.
27.
28.
Lim JY, Lee SH, Cha YS, Park HS, Sunwoo S (2001) Reliability and validity of anxiety screening scale. J Korean Acad Fam Med 22(8):1224–1232
29.
Pignone MP, Gaynes BN, Rushton JL, Burchell CM, Orleans CT, Mulrow CD, Lohr KN (2002) Screening for depression in adults: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 136(10):765–776CrossRefPubMed
30.
Choi HS, Choi JH, Park KH, Joo KJ, Ga H, Ko HJ, Kim SR (2007) Standardization of the Korean version of Patient Health Questionnaire-9 as a screening instrument for major depressive disorder. J Korean Acad Fam Med 28(2):114–119
31.
Rubin DB, Little RJ (2002) Statistical analysis with missing data. J Wiley & Sons, Hoboken
32.
Peng KP, Wang SJ (2014) Epidemiology of headache disorders in the Asia-pacific region. Headache 54(4):610–618CrossRefPubMed
33.
Rains JC, Penzien DB, Lipchik GL, Ramadan NM (2001) Diagnosis of migraine: empirical analysis of a large clinical sample of atypical migraine (IHS 1.7) patients and proposed revision of the IHS criteria. Cephalalgia 21(5):584–595CrossRefPubMed
34.
Bigal ME, Kolodner KB, Lafata JE, Leotta C, Lipton RB (2006) Patterns of medical diagnosis and treatment of migraine and probable migraine in a health plan. Cephalalgia 26(1):43–49CrossRefPubMed
35.
Patel NV, Bigal ME, Kolodner KB, Leotta C, Lafata JE, Lipton RB (2004) Prevalence and impact of migraine and probable migraine in a health plan. Neurology 63(8):1432–1438CrossRefPubMed
36.
Vukovic V, Plavec D, Pavelin S, Janculjak D, Ivankovic M, Demarin V (2010) Prevalence of migraine, probable migraine and tension-type headache in the Croatian population. Neuroepidemiology 35(1):59–65CrossRefPubMed
37.
Yeo BK, Perera IS, Kok LP, Tsoi WF (1996) Insomnia in the community. Singapore Med J 37(3):282–284PubMed
38.
Kim K, Uchiyama M, Okawa M, Liu X, Ogihara R (2000) An epidemiological study of insomnia among the Japanese general population. Sleep 23(1):41–47PubMed
39.
Ohayon MM, Hong SC (2002) Prevalence of insomnia and associated factors in South Korea. J Psychosom Res 53(1):593–600CrossRefPubMed
40.
Sivertsen B, Lallukka T, Salo P, Pallesen S, Hysing M, Krokstad S, Simon O (2014) Insomnia as a risk factor for ill health: results from the large population-based prospective HUNT Study in Norway. J Sleep Res 23(2):124–132CrossRefPubMed
41.
Esposito M, Roccella M, Parisi L, Gallai B, Carotenuto M (2013) Hypersomnia in children affected by migraine without aura: a questionnaire-based case–control study. Neuropsychiatr Dis Treat 9:289–294PubMedPubMedCentral
42.
Dosi C, Riccioni A, Della Corte M, Novelli L, Ferri R, Bruni O (2013) Comorbidities of sleep disorders in childhood and adolescence: focus on migraine. Nat Sci Sleep 5:77–85PubMedPubMedCentral
43.
Walters AB, Hamer JD, Smitherman TA (2014) Sleep disturbance and affective comorbidity among episodic migraineurs. Headache 54(1):116–124CrossRefPubMed
44.
Vgontzas A, Cui L, Merikangas KR (2008) Are sleep difficulties associated with migraine attributable to anxiety and depression? Headache 48(10):1451–1459CrossRefPubMedPubMedCentral
45.
Sauro KM, Rose MS, Becker WJ, Christie SN, Giammarco R, Mackie GF, Eloff AG, Gawel MJ (2010) HIT-6 and MIDAS as measures of headache disability in a headache referral population. Headache 50(3):383–395CrossRefPubMed
Metadata
Title
Insomnia in probable migraine: a population-based study
Authors
Jiyoung Kim
Soo-Jin Cho
Won-Joo Kim
Kwang Ik Yang
Chang-Ho Yun
Min Kyung Chu
Publication date
01-12-2016
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/s10194-016-0681-2

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