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Published in: Journal of the Association for Research in Otolaryngology 1/2024

Open Access 09-02-2024 | Opinions

Inner Ear Organoids: Strengths and Limitations

Authors: Giulia Pianigiani, Marta Roccio

Published in: Journal of the Association for Research in Otolaryngology | Issue 1/2024

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Abstract

Inner ear organoids derived from differentiation of human pluripotent stem cells have recently gained momentum as tools to study inner ear development and developmental defects. An additional exciting aspect about this technology is represented by its translational potential, specifically, the use of organoids to validate therapeutics for hearing and balance restoration on human/patient-specific cells. This latter aspect will be briefly discussed here including opportunities and current limitations.
Literature
10.
go back to reference Nie J, Hashino E (2020) Generation of inner ear organoids from human pluripotent stem cells. Methods Cell Biol 159:303–321 Nie J, Hashino E (2020) Generation of inner ear organoids from human pluripotent stem cells. Methods Cell Biol 159:303–321
Metadata
Title
Inner Ear Organoids: Strengths and Limitations
Authors
Giulia Pianigiani
Marta Roccio
Publication date
09-02-2024
Publisher
Springer US
Published in
Journal of the Association for Research in Otolaryngology / Issue 1/2024
Print ISSN: 1525-3961
Electronic ISSN: 1438-7573
DOI
https://doi.org/10.1007/s10162-024-00929-2

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