Published in:
Open Access
09-02-2024 | Opinions
Inner Ear Organoids: Strengths and Limitations
Authors:
Giulia Pianigiani, Marta Roccio
Published in:
Journal of the Association for Research in Otolaryngology
|
Issue 1/2024
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Abstract
Inner ear organoids derived from differentiation of human pluripotent stem cells have recently gained momentum as tools to study inner ear development and developmental defects. An additional exciting aspect about this technology is represented by its translational potential, specifically, the use of organoids to validate therapeutics for hearing and balance restoration on human/patient-specific cells. This latter aspect will be briefly discussed here including opportunities and current limitations.