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Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 5/2004

01-05-2004 | Clinical Investigation

Infracyanine-assisted internal limiting membrane peeling in macular hole repair: Does it make a difference?

Authors: Kelvin Rivett, Louis Kruger, Sarah Radloff

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 5/2004

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Abstract

Purpose

To investigate whether Infracyanine-assisted internal limiting membrane (ILM) peeling in macular hole repair affects the anatomical and functional outcome and complication rate.

Methods

A retrospective analysis of 139 consecutive cases of stage 2 and stage 3 macular hole repairs with or without Infracyanine-assisted ILM peeling.

Results

There were 67 eyes with Infracyanine staining of the ILM and 72 eyes in the non-ILM-stained group. The results are analyzed functionally, anatomically and in terms of complications. A similar anatomical and functional closure rate was obtained with one unclosed macular hole in the stained group and two in the non-stained group (P=1.0). Fifty-two percent of the eyes in the stained group and 59% of those in the non-stained group achieved 0.5 vision or better (P=0.40). The mean postoperative vision was 0.55 in the stained group and 0.54 in the non-stained group (P=0.65). The mean improvement in vision was 0.40 in the stained group and 0.36 in the non-stained group (P=0.21).

Conclusion

Anatomical and functional results are similar with or without Infracyanine-assisted ILM peeling. There was no apparent adverse effect of Infracyanine use on visual function, and no apparent retinal toxicity was found.
Literature
1.
go back to reference Brooks HL Jr (2000) Macular hole surgery with and without internal limiting membrane peeling. Ophthalmology 107:1939–1949CrossRefPubMed Brooks HL Jr (2000) Macular hole surgery with and without internal limiting membrane peeling. Ophthalmology 107:1939–1949CrossRefPubMed
2.
go back to reference Da Mata AP, Burk SE, Riemann CD, Rosa RH Jr, Synder ME, Petersen MR, Foster RE (2001) Indocyanine green-assisted peeling of the retinal internal limiting membrane during vitrectomy surgery for macular hole repair. Ophthalmology 108 (7):1187–1192PubMed Da Mata AP, Burk SE, Riemann CD, Rosa RH Jr, Synder ME, Petersen MR, Foster RE (2001) Indocyanine green-assisted peeling of the retinal internal limiting membrane during vitrectomy surgery for macular hole repair. Ophthalmology 108 (7):1187–1192PubMed
3.
go back to reference Engelbrecht NE, Freeman J, Sternberg P Jr, Aaberg TM Sr, Aaberg TM Jr, Martin DF, Sippy BD (2002) Retinal pigment changes after macular hole surgery with indocyanine green-assisted internal limiting membrane peeling. Am J Ophthalmology 133 (1):89–94CrossRef Engelbrecht NE, Freeman J, Sternberg P Jr, Aaberg TM Sr, Aaberg TM Jr, Martin DF, Sippy BD (2002) Retinal pigment changes after macular hole surgery with indocyanine green-assisted internal limiting membrane peeling. Am J Ophthalmology 133 (1):89–94CrossRef
4.
go back to reference Freeman JY, Engelbrecht NE, Aaberg TM Jr, et al. (2001) Retinal and RPE changes after ICG-assisted ILM peeling in macular hole surgery (abstract). Invest Ophthalmol Vis Sci 42:S729 Freeman JY, Engelbrecht NE, Aaberg TM Jr, et al. (2001) Retinal and RPE changes after ICG-assisted ILM peeling in macular hole surgery (abstract). Invest Ophthalmol Vis Sci 42:S729
5.
go back to reference Gandorfer A, Haritoglou C, Gass CA, Ulbig MW, Kampik A (2001) Indocyanine green-assisted peeling of the internal limiting membrane may cause retinal damage. Am J Ophthalmol 132 (3):431–433 Gandorfer A, Haritoglou C, Gass CA, Ulbig MW, Kampik A (2001) Indocyanine green-assisted peeling of the internal limiting membrane may cause retinal damage. Am J Ophthalmol 132 (3):431–433
6.
go back to reference Gandorfer A, Messmer EM, Ulbig MW, Kampik A (2001) Indocyanine green selectively stains the internal limiting membrane. Am J Ophthalmol 131 (3):387–388PubMed Gandorfer A, Messmer EM, Ulbig MW, Kampik A (2001) Indocyanine green selectively stains the internal limiting membrane. Am J Ophthalmol 131 (3):387–388PubMed
7.
go back to reference Gandorfer A, Haritoglou C, Gandorfer A, Kampik A (2003) Retinal damage from indocyanine green in experimental macular surgery. Invest Ophthalmol Vis Sci 44 (1):316–323CrossRefPubMed Gandorfer A, Haritoglou C, Gandorfer A, Kampik A (2003) Retinal damage from indocyanine green in experimental macular surgery. Invest Ophthalmol Vis Sci 44 (1):316–323CrossRefPubMed
8.
go back to reference Gass JDM (1995) Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol 119:752–759 Gass JDM (1995) Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol 119:752–759
9.
go back to reference Haritoglou C, Gandorfer A, Gass CA, Schaumberger M, Ulbig MW, Kampik A (2002) Indocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation. Am J Ophthalmol 134(6):836–841CrossRef Haritoglou C, Gandorfer A, Gass CA, Schaumberger M, Ulbig MW, Kampik A (2002) Indocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation. Am J Ophthalmol 134(6):836–841CrossRef
10.
go back to reference Hee MR, Puliafito CA, Wong C, et al (1995) Optical coherence tomography of macular holes. Ophthalmology 102:748–756PubMed Hee MR, Puliafito CA, Wong C, et al (1995) Optical coherence tomography of macular holes. Ophthalmology 102:748–756PubMed
11.
go back to reference Johnson MW (2002) Improvements in the understanding and treatment of macular hole. Curr Opin Ophthalmol 13 (3):152–160CrossRefPubMed Johnson MW (2002) Improvements in the understanding and treatment of macular hole. Curr Opin Ophthalmol 13 (3):152–160CrossRefPubMed
12.
go back to reference Johnson MW, van Niekerk MR, Meyer KA (2001) Perifoveal vitreous detachment is the primary pathogenic event in idiopathic macular hole formation. Arch Ophthalmol 119:215–222PubMed Johnson MW, van Niekerk MR, Meyer KA (2001) Perifoveal vitreous detachment is the primary pathogenic event in idiopathic macular hole formation. Arch Ophthalmol 119:215–222PubMed
13.
go back to reference Mester V, Kuhn F (2000) Internal limiting membrane removal in the management of full-thickness macular holes. Am J Ophthalmol 129:769–777 Mester V, Kuhn F (2000) Internal limiting membrane removal in the management of full-thickness macular holes. Am J Ophthalmol 129:769–777
14.
go back to reference Park DW, Sipperley JO, Sneed SR, et al (1999) Macular hole surgery with internal-limiting membrane peeling and intravitreous air. Ophthalmology 106:1932–1398 Park DW, Sipperley JO, Sneed SR, et al (1999) Macular hole surgery with internal-limiting membrane peeling and intravitreous air. Ophthalmology 106:1932–1398
15.
go back to reference Sippy BD, Engelbrecht NE, Hubbard GB, Moriarty SE, Jiang S, Aaberg TM Jr, Aaberg TM Sr, Grossniklaus HE, Sternberg P Jr (2001) Indocyanine green effect on cultured human retinal pigment epithelial cells: implication for macular hole surgery. Am J Ophthalmol 132 (3):433–435 Sippy BD, Engelbrecht NE, Hubbard GB, Moriarty SE, Jiang S, Aaberg TM Jr, Aaberg TM Sr, Grossniklaus HE, Sternberg P Jr (2001) Indocyanine green effect on cultured human retinal pigment epithelial cells: implication for macular hole surgery. Am J Ophthalmol 132 (3):433–435
16.
go back to reference Stalmans P, Parys-Vanginderdeuren R, De Vos R, Feron EJ (2001) ICG staining of the inner limiting membrane facilitates its removal during surgery for macular holes and puckers. Bull Soc Belge Ophtalmol 281:21–26PubMed Stalmans P, Parys-Vanginderdeuren R, De Vos R, Feron EJ (2001) ICG staining of the inner limiting membrane facilitates its removal during surgery for macular holes and puckers. Bull Soc Belge Ophtalmol 281:21–26PubMed
17.
go back to reference Stalmans P, Van Eken EH, Veckeneer M, Feron EJ, Stalmans I (2002) Toxic effect of indocyanine green on retinal pigment epithelium related to osmotic effects of the solvent. Am J Ophthalmol 134:282–285 Stalmans P, Van Eken EH, Veckeneer M, Feron EJ, Stalmans I (2002) Toxic effect of indocyanine green on retinal pigment epithelium related to osmotic effects of the solvent. Am J Ophthalmol 134:282–285
18.
go back to reference Van der Moere A, Stalmans P (2003) Anatomical and visual outcome of macular hole surgery with Infracyanine green-assisted peeling of the internal limiting membrane, endodrainage, and silicone oil tamponade. Am J Ophthalmol 136 (5):879–887CrossRefPubMed Van der Moere A, Stalmans P (2003) Anatomical and visual outcome of macular hole surgery with Infracyanine green-assisted peeling of the internal limiting membrane, endodrainage, and silicone oil tamponade. Am J Ophthalmol 136 (5):879–887CrossRefPubMed
Metadata
Title
Infracyanine-assisted internal limiting membrane peeling in macular hole repair: Does it make a difference?
Authors
Kelvin Rivett
Louis Kruger
Sarah Radloff
Publication date
01-05-2004
Publisher
Springer-Verlag
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 5/2004
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-003-0857-8

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