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Critical Care
Published in: Critical Care 1/2021

Open Access 01-12-2021 | Influenza Virus | Research Letter

Interleukin-34: an important modifier in the pathogenesis of influenza pneumonia

Authors: Banglao Xu, Xue Lin, Yi Gong, Xiaofei Lai, Lei Ren, Ju Cao

Published in: Critical Care | Issue 1/2021

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Excerpt

Influenza is an acute respiratory virus infection of worldwide health importance [1, 2]. Interleukin-34 (IL-34) is an important inflammatory cytokine [3, 4]. We tested here whether IL-34 contributes to the immunopathology of influenza virus infection. …
Literature
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Ni YN, Chen G, Sun J, Liang BM, Liang ZA. The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis. Crit Care. 2019;23:99.CrossRef
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Kenney AD, Li Z, Bian Z, Zhou X, Li H, Whitson BA, et al. Recombinant MG53 protein protects mice from lethal influenza virus infection. Am J Respir Crit Care Med. 2021;203:254–7.CrossRef
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Lin X, Luo H, Yan X, Song Z, Gao X, Xia Y, et al. Interleukin-34 ameliorates survival and bacterial clearance in polymicrobial sepsis. Crit Care Med. 2018;46:e584–90.CrossRef
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Matute-Bello G, Downey G, Moore BB, Groshong SD, Matthay MA, Slutsky AS, et al. An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol. 2011;44:725–38.CrossRef
Metadata
Title
Interleukin-34: an important modifier in the pathogenesis of influenza pneumonia
Authors
Banglao Xu
Xue Lin
Yi Gong
Xiaofei Lai
Lei Ren
Ju Cao
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2021
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-021-03708-0

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