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Archives of Orthopaedic and Trauma Surgery

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01-09-2015 | Orthopaedic Surgery

Influence of vertebral column distraction on spinal cord volume: an experimental study in a goat model

Authors: Feng Qiu, Jin-Cheng Yang, Xiang-Yang Ma, Jun-Jie Xu, Qing-Lei Yang, Xin Zhou, Yao-Sheng Xiao, Hai-Sheng Hu, Li-Hui Xia

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 9/2015

Abstract

Introduction

Spinal cord injury may be related to excessive distraction of the spinal cord during surgical correction of spinal deformities by vertebral column resection. This study aimed to investigate how vertebral column distraction influences spinal cord volume to establish the safe range in a goat model.

Materials and methods

A vertebral column resection was performed on the tenth thoracic vertebra of 11 goats. The spinal cord was distracted until the somatosensory evoked potential signals were decreased to 50 % from baseline amplitude or were delayed by 10 % of the baseline peak latency. The osteotomy segment was stabilized with a PEEK mesh cage filled with bone graft, and the pedicle screws on the rods were then tightened in this position. Spinal cord volume was calculated using Mimics software, and T10 height, disk height, osteotomy segment height, and spinal segment height were measured using the MRI image workstation.

Results

Three goats were excluded, and data obtained from the eight remaining goats were analyzed. The safe limit of distraction distance was 11.8 ± 3.65 mm, and the distraction distance was strongly correlated with the difference between the pre- and postoperative measurements (d value) of spinal cord volume per 1 mm of osteotomy segment height (r = −0.952, p < 0.001), but was not correlated with T10 body height (r = 0.16, p = 0.71), spinal segment height (r = 0.29, p = 0.49), disk height (r = −0.12, p = 0.98), or the d value (pre–post) of spinal cord volume per 1 mm of spinal segment height (r = 0.45, p = 0.26). The mean d value (pre–post) of spinal cord volume per 1 mm of osteotomy segment height was 10.05 ± 0.02 mm³ (range 10.02–10.08 mm³).

Conclusion

The maximum change in spinal cord volume per 1-mm change in height was in the osteotomy segment, and its safe limit was 10.05 ± 0.02 mm³. The safe limit of spinal cord distraction can be calculated using the spinal cord volume per unit 1-mm change in height.

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Title: Influence of vertebral column distraction on spinal cord volume: an experimental study in a goat model
Authors: Feng Qiu
Jin-Cheng Yang
Xiang-Yang Ma
Jun-Jie Xu
Qing-Lei Yang
Xin Zhou
Yao-Sheng Xiao
Hai-Sheng Hu
Li-Hui Xia
Publication date: 01-09-2015
Publisher: Springer Berlin Heidelberg
Published in: Archives of Orthopaedic and Trauma Surgery / Issue 9/2015
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI: https://doi.org/10.1007/s00402-015-2264-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Influence of vertebral column distraction on spinal cord volume: an experimental study in a goat model

Abstract

Introduction

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Materials and methods

Results

Conclusion

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