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Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Research article

Influence of socioeconomic status on antipsychotic prescriptions among youth in France

Authors: Olivier Bonnot, Mélanie Dufresne, Paula Herrera, Emmanuelle Michaud, Jacques Pivette, Anicet Chaslerie, Anne Sauvaget, Caroline Vigneau

Published in: BMC Psychiatry | Issue 1/2017

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Abstract

Background

Recent studies analysing the trends in antipsychotic (AP) prescriptions for children and adolescents have raised concerns regarding the influence of socioeconomic status. Previous findings have also shown variable prescription rates for first-generation (FG) and second-generation (SG) APs.

Method

Our objectives were to assess the proportion of patients from low-income families receiving APs and the most commonly prescribed APs in France. We conducted a descriptive analysis of AP drugs dispensed during a 1-year period (July 1, 2013–June 30, 2014) in a northwestern region of France with 941,857 subjects less than 18 years old. All data were extracted from an exhaustive, individual and anonymous social security database. We obtained each subject’s socioeconomic status (by identifying their affiliation with a specific social security program) and also collected sociodemographic data, drug type, prescribing and dispensing dates and amount, and prescriber type (e.g., hospital physician, general practitioner, psychiatrist, paediatrician).

Results

There were two main novel findings. First, we found that the proportion of patients with AP prescriptions was nearly ten times higher in low-income families than in the general population: 35.9% of CMU-C patients compared to 3.7% in all of Pays de la Loire (X 2 = 7875.1, p < 0.001). Additionally, we found a higher rate of FGAP than SGAP prescriptions (65% vs. 57%).

Conclusions

Our study suggests two types of AP misuse that could provide interesting targets for public healthcare interventions.
First, our results strongly suggest an over-representation of patients from low-income families. Low-income families primarily resided in areas with low physician density and appeared to receive drugs to treat their conditions more frequently than other individuals. This increased prescription rate is a public health issue, potentially requiring political action. Second, the use of FGAPs did not adhere to the latest recommendations for drug use in this population, and this discrepancy should be addressed with informational campaigns targeted to medical practitioners.
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Metadata
Title
Influence of socioeconomic status on antipsychotic prescriptions among youth in France
Authors
Olivier Bonnot
Mélanie Dufresne
Paula Herrera
Emmanuelle Michaud
Jacques Pivette
Anicet Chaslerie
Anne Sauvaget
Caroline Vigneau
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1232-3

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