Published in:
01-02-2004 | Poster presentation
Influence of dobutamine and norepinephrine and cerebral blood flow: preliminary data
Authors:
A Donati, R Coltrinari, S Loggi, R Pallotto, M Ruzzi, M Scarcella, I Valentini, P Pelaia
Published in:
Critical Care
|
Special Issue 1/2004
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Excerpt
Severe head trauma patients are often deeply sedated and this can cause a myocardial depression with hypotension and low cardiac output. Hypotension is very dangerous, particularly in patients with cerebral oedema and high intracranial pressure. Dobutamine and/or norepinephrine are usually given to restore myocardial performance and increase blood pressure and, consequently, cerebral perfusion pressure (PPC). The effects of these two drugs on the cerebral blood flow (CBF) are unknown. The aim of this study is to measure CBF and central hemodynamics in a group of patients with severe head trauma (Glasgow Coma Scale < 8), first using dobutamine and then norepinephrine. …
