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Current Nutrition Reports

Inflammation: a New Player in the Link Between Mediterranean Diet and Diabetes Mellitus: a Review

  • 01-09-2017
  • Cardiovascular Disease (JHY Wu, Section Editor)
Published in:
Authors
Efi Koloverou
Demosthenes B. Panagiotakos
Published in
Current Nutrition Reports | Issue 3/2017

Abstract

Purpose of Review

Mediterranean diet (MD) has been inversely linked with insulin resistance and diabetes, while inflammation is recognized as a common denominator in cardiometabolic disorders. Here, we review the synergistic effect between MD and inflammation, the anti-inflammatory properties of core MD components, and the possible biological mechanisms linking nutrients with inflammation.

Recent Findings

MD is abundant in anti-inflammatory foods, like whole grains, fruits and vegetables, wine, olive oil, nuts, and fish. This results in a high intake of various polyphenols, as well as high unsaturated/saturated and n3/n6 fatty acid ratios, leading through different mechanisms, such as oxidative stress reduction, alteration of NF-κB, PPAR-γ pathways, prebiotic function on gut microbiota, and others, to an attenuation of inflammation state.

Summary

MD is comprised by a plethora of foods, with anti-inflammatory potential, so its observed anti-diabetic effect could, at least partially, be ascribed to an attenuation of inflammation state.
Title
Inflammation: a New Player in the Link Between Mediterranean Diet and Diabetes Mellitus: a Review
Authors
Efi Koloverou
Demosthenes B. Panagiotakos
Publication date
01-09-2017
Publisher
Springer US
Published in
Current Nutrition Reports / Issue 3/2017
Electronic ISSN: 2161-3311
DOI
https://doi.org/10.1007/s13668-017-0209-7
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