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Published in: BMC Complementary Medicine and Therapies 1/2023

Open Access 01-12-2023 | Infertility | Research

Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study

Authors: Su-Ji Choi, Dong-Il Kim

Published in: BMC Complementary Medicine and Therapies | Issue 1/2023

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Abstract

Background

This study aimed to investigate the prescription of traditional herbal medicines for the treatment of unexplained female infertility in Korea. By analyzing the relationships among the prescriptions and between the prescriptions and treatment outcomes, we aimed to confirm the utilization of standardized prescriptions and the effectiveness of this standardization.

Methods

The data were derived from the “support projects” of the local government for infertile women to receive Korean medical treatments. The presciption data of 453 participants from 2017 to 2018 were analyzed. Data preprocessing, frequency analysis, and network analysis were conducted. For network analysis, the characteristics of the herbal medicine prescriptions were used to calculate the degree centrality, closeness centrality and eigenvector centrality. Modularity clustering was also performed for cluster analysis.

Results

Fifty different prescriptions were used, among which only 22 were used for participants who became pregnant. The recommended standard prescriptions for support projects were used frequently. “BaeranChacksangBang” showed the highest level of in-degree centrality. Among the prescriptions for participants who became pregnant, “JogyeongJongokTang” and “BaeranChacksangBang” were the most influential nodes. “BaeranChacksangBang,AnjeonYicheonTang,YukLinZu” and “JogyeongJongokTang” had high closeness centrality among the prescriptions for participants who became pregnant. Clustering analysis of the prescriptions for participants who became pregnant revealed that the prescriptions showed the best modularity when divided into five groups.

Conclusions

These findings depict the utilization of Korean herbal medicine in the real world and the dynamics underlying the herbal medicine prescription patterns for infertile women.
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Literature
4.
go back to reference Hruska KS, Furth PA, Seifer DB, Sharara FI, Flaws JA. Environmental factors in infertility. Clin Obstet Gynecol. 2000;43(4):821–9.CrossRefPubMed Hruska KS, Furth PA, Seifer DB, Sharara FI, Flaws JA. Environmental factors in infertility. Clin Obstet Gynecol. 2000;43(4):821–9.CrossRefPubMed
5.
go back to reference Saleem H, Chaudhry AG, Jabbar A, Mishal S. Late marriages and infertility: an anthropological analysis on health. The Explorer Islamabad: Journal of Social Sciences. 2015;1(7):246–50. Saleem H, Chaudhry AG, Jabbar A, Mishal S. Late marriages and infertility: an anthropological analysis on health. The Explorer Islamabad: Journal of Social Sciences. 2015;1(7):246–50.
6.
go back to reference Kim D. Korean medicine clinical practice guideline of female infertility. Seoul: The Association of Korean Medicine; 2018. Kim D. Korean medicine clinical practice guideline of female infertility. Seoul: The Association of Korean Medicine; 2018.
7.
go back to reference Kim D. Oriental medicine clinical practice guideline of infertility. Seoul: The Association of Korean Medicine; 2010. p. 46. Kim D. Oriental medicine clinical practice guideline of infertility. Seoul: The Association of Korean Medicine; 2010. p. 46.
12.
go back to reference Lee SS. Methodology of network analysis. Seoul: NonHyong; 2012. Lee SS. Methodology of network analysis. Seoul: NonHyong; 2012.
13.
go back to reference Wasserman S, Faust K. Social network analysis: methods and applications. Cambridge: Cambridge University Press; 1994.CrossRef Wasserman S, Faust K. Social network analysis: methods and applications. Cambridge: Cambridge University Press; 1994.CrossRef
14.
go back to reference Freeman LC. Centrality in social networks: conceptual clarification. In: Social network: critical concepts in sociology, vol. 1. Londres: Routledge; 2002. p. 238–63. Freeman LC. Centrality in social networks: conceptual clarification. In: Social network: critical concepts in sociology, vol. 1. Londres: Routledge; 2002. p. 238–63.
16.
go back to reference Bonacich P. Factoring and weighting approaches to status scores and clique identification. J Math Sociol. 1972;2(1):113–20.CrossRef Bonacich P. Factoring and weighting approaches to status scores and clique identification. J Math Sociol. 1972;2(1):113–20.CrossRef
27.
go back to reference Lee SJ, Lim JY, Lee DK, Lee TK. Effect of Jokyong-Jongok-tang on the fertilization and maturation of immature oocytes in bovine. J Orient Obstet Gynecol. 1999;12:134–47. Lee SJ, Lim JY, Lee DK, Lee TK. Effect of Jokyong-Jongok-tang on the fertilization and maturation of immature oocytes in bovine. J Orient Obstet Gynecol. 1999;12:134–47.
Metadata
Title
Utilization of traditional herbal medicine formulas for unexplained female infertility in Korea: a retrospective study
Authors
Su-Ji Choi
Dong-Il Kim
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Complementary Medicine and Therapies / Issue 1/2023
Electronic ISSN: 2662-7671
DOI
https://doi.org/10.1186/s12906-023-04192-5

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