Skip to main content
Top
Published in: Pediatric Nephrology 5/2015

01-05-2015 | Original Article

Infectious outcomes following gastrostomy in children receiving peritoneal dialysis

Authors: Chanel Prestidge, Jane Ronaldson, William Wong, Maria Stack, Tonya Kara

Published in: Pediatric Nephrology | Issue 5/2015

Login to get access

Abstract

Background

Early institution of enteral feeding in paediatric end-stage kidney disease (ESKD) is recommended. For patients on peritoneal dialysis (PD) there is concern that gastrostomy tube (GT) insertion may be complicated by increased peritonitis, in particular fungal. Our unit favours early planned GT insertion, and for those with late presentation, there is prompt consideration of GT insertion following dialysis initiation. This study evaluates our rates of peritonitis with GT insertion following or concurrent with PD initiation.

Methods

This was a retrospective, single-centre, cross-sectional study of of 17 New Zealand children with ESKD who received PD in the period 2000–2011. Inclusion criteria were GT placement while on PD or initiation of PD within 72 h of GT insertion.

Results

There were no cases of fungal peritonitis among the 17 children; however, two cases of early peritonitis with organisms derived from the gastrointestinal tract were identified. No statistically significant difference was found between incident rates of bacterial peritonitis before GT placement (0.6 episodes per patient-year; 95 % confidence interval (CI) 0.26–1.18) and post-GT placement (1.21 episodes per patient-year; 95 % CI 0.69–1.97).

Conclusion

Fungal peritonitis has never been encountered by out unit during its many years of experience in GT placement in patients without advanced malnutrition. When children on PD have insufficient dietary intake to maintain appropriate growth velocity, enteral feeding should be initiated promptly. A GT is considered to be safe for long-term use in selected patients.
Literature
1.
go back to reference Rees L, Mak RH (2011) Nutrition and growth in children with chronic kidney disease. Nat Rev Nephrol 7:615–623CrossRefPubMed Rees L, Mak RH (2011) Nutrition and growth in children with chronic kidney disease. Nat Rev Nephrol 7:615–623CrossRefPubMed
2.
go back to reference Ramage IJ, Geary DF, Harvey E, Secker DJ, Balfe JA, Balfe JW (1999) Efficacy of gastrostomy feeding in infants and older children receiving chronic peritoneal dialysis. Perit Dial Int 19:231–236PubMed Ramage IJ, Geary DF, Harvey E, Secker DJ, Balfe JA, Balfe JW (1999) Efficacy of gastrostomy feeding in infants and older children receiving chronic peritoneal dialysis. Perit Dial Int 19:231–236PubMed
3.
go back to reference Ramage IJ, Harvey E, Geary DF, Hebert D, Balfe JA, Balfe JW (1999) Complications of gastrostomy feeding in children receiving peritoneal dialysis. Pediatr Nephrol 13:249–252CrossRefPubMed Ramage IJ, Harvey E, Geary DF, Hebert D, Balfe JA, Balfe JW (1999) Complications of gastrostomy feeding in children receiving peritoneal dialysis. Pediatr Nephrol 13:249–252CrossRefPubMed
4.
go back to reference Warady BA, Bakkaloglu S, Newland J, Cantwell M, Verrina E, Neu A, Chadha V, Yap HK, Schaefer F (2012) Consensus guidelines for the prevention and treatment of catheter-related infections and peritonitis in pediatric patients receiving peritoneal dialysis: 2012 update. Perit Dial Int 32[Suppl 2]:S32–S86CrossRefPubMedCentralPubMed Warady BA, Bakkaloglu S, Newland J, Cantwell M, Verrina E, Neu A, Chadha V, Yap HK, Schaefer F (2012) Consensus guidelines for the prevention and treatment of catheter-related infections and peritonitis in pediatric patients receiving peritoneal dialysis: 2012 update. Perit Dial Int 32[Suppl 2]:S32–S86CrossRefPubMedCentralPubMed
5.
go back to reference Ledermann SE, Spitz L, Moloney J, Rees L, Trompeter RS (2002) Gastrostomy feeding in infants and children on peritoneal dialysis. Pediatr Nephrol 17:246–250CrossRefPubMed Ledermann SE, Spitz L, Moloney J, Rees L, Trompeter RS (2002) Gastrostomy feeding in infants and children on peritoneal dialysis. Pediatr Nephrol 17:246–250CrossRefPubMed
6.
go back to reference Murugasu B, Conley SB, Lemire JM, Portman RJ (1991) Fungal peritonitis in children treated with peritoneal dialysis and gastrostomy feeding. Pediatr Nephrol 5:620–621CrossRefPubMed Murugasu B, Conley SB, Lemire JM, Portman RJ (1991) Fungal peritonitis in children treated with peritoneal dialysis and gastrostomy feeding. Pediatr Nephrol 5:620–621CrossRefPubMed
7.
go back to reference von Schnakenburg C, Feneberg R, Plank C, Zimmering M, Arbeiter K, Bald M, Fehrenbach H, Griebel M, Licht C, Konrad M, Timmermann K, Kemper MJ (2006) Percutaneous endoscopic gastrostomy in children on peritoneal dialysis. Perit Dial Int 26:69–77 von Schnakenburg C, Feneberg R, Plank C, Zimmering M, Arbeiter K, Bald M, Fehrenbach H, Griebel M, Licht C, Konrad M, Timmermann K, Kemper MJ (2006) Percutaneous endoscopic gastrostomy in children on peritoneal dialysis. Perit Dial Int 26:69–77
8.
go back to reference Lindley RM, Williams AR, Fraser N, Shenoy MU (2012) Synchronous laparoscopic-assisted percutaneous endoscopic gastrostomy and peritoneal dialysis catheter placement is a valid alternative to open surgery. J Pediatr Urol 8:527–530CrossRefPubMed Lindley RM, Williams AR, Fraser N, Shenoy MU (2012) Synchronous laparoscopic-assisted percutaneous endoscopic gastrostomy and peritoneal dialysis catheter placement is a valid alternative to open surgery. J Pediatr Urol 8:527–530CrossRefPubMed
9.
go back to reference Fine RN, Martz K, Stablein D (2010) What have 20 years of data from the North American Pediatric Renal Transplant Cooperative Study taught us about growth following renal transplantation in infants, children, and adolescents with end-stage renal disease? Pediatr Nephrol 25:739–746CrossRefPubMed Fine RN, Martz K, Stablein D (2010) What have 20 years of data from the North American Pediatric Renal Transplant Cooperative Study taught us about growth following renal transplantation in infants, children, and adolescents with end-stage renal disease? Pediatr Nephrol 25:739–746CrossRefPubMed
10.
go back to reference Furth SL, Stablein D, Fine RN, Powe NR, Fivush BA (2002) Adverse clinical outcomes associated with short stature at dialysis initiation: a report of the North American Pediatric Renal Transplant Cooperative Study. Pediatrics 109:909–913CrossRefPubMed Furth SL, Stablein D, Fine RN, Powe NR, Fivush BA (2002) Adverse clinical outcomes associated with short stature at dialysis initiation: a report of the North American Pediatric Renal Transplant Cooperative Study. Pediatrics 109:909–913CrossRefPubMed
11.
go back to reference Wong CS, Gipson DS, Gillen DL, Emerson S, Koepsell T, Sherrard DJ, Watkins SL, Stehman-Breen C (2000) Anthropometric measures and risk of death in children with end-stage renal disease. Am J Kidney Dis 36:811–819CrossRefPubMed Wong CS, Gipson DS, Gillen DL, Emerson S, Koepsell T, Sherrard DJ, Watkins SL, Stehman-Breen C (2000) Anthropometric measures and risk of death in children with end-stage renal disease. Am J Kidney Dis 36:811–819CrossRefPubMed
12.
go back to reference Coleman JE, Watson AR, Rance CH, Moore E (1998) Gastrostomy buttons for nutritional support on chronic dialysis. Nephrol Dial Transplant 13:2041–2046CrossRefPubMed Coleman JE, Watson AR, Rance CH, Moore E (1998) Gastrostomy buttons for nutritional support on chronic dialysis. Nephrol Dial Transplant 13:2041–2046CrossRefPubMed
13.
go back to reference Kari JA, Gonzalez C, Ledermann SE, Shaw V, Rees L (2000) Outcome and growth of infants with severe chronic renal failure. Kidney Int 57:1681–1687CrossRefPubMed Kari JA, Gonzalez C, Ledermann SE, Shaw V, Rees L (2000) Outcome and growth of infants with severe chronic renal failure. Kidney Int 57:1681–1687CrossRefPubMed
14.
go back to reference Ledermann SE, Scanes ME, Fernando ON, Duffy PG, Madden SJ, Trompeter RS (2000) Long-term outcome of peritoneal dialysis in infants. J Pediatr 136:24–29CrossRefPubMed Ledermann SE, Scanes ME, Fernando ON, Duffy PG, Madden SJ, Trompeter RS (2000) Long-term outcome of peritoneal dialysis in infants. J Pediatr 136:24–29CrossRefPubMed
15.
go back to reference Ledermann SE, Shaw V, Trompeter RS (1999) Long-term enteral nutrition in infants and young children with chronic renal failure. Pediatr Nephrol 13:870–875CrossRefPubMed Ledermann SE, Shaw V, Trompeter RS (1999) Long-term enteral nutrition in infants and young children with chronic renal failure. Pediatr Nephrol 13:870–875CrossRefPubMed
16.
17.
go back to reference Parekh RS, Flynn JT, Smoyer WE, Milne JL, Kershaw DB, Bunchman TE, Sedman AB (2001) Improved growth in young children with severe chronic renal insufficiency who use specified nutritional therapy. J Am Soc Nephrol 12:2418–2426PubMed Parekh RS, Flynn JT, Smoyer WE, Milne JL, Kershaw DB, Bunchman TE, Sedman AB (2001) Improved growth in young children with severe chronic renal insufficiency who use specified nutritional therapy. J Am Soc Nephrol 12:2418–2426PubMed
19.
go back to reference Strife CF, Quinlan M, Mears K, Davey ML, Clardy C (1986) Improved growth of three uremic children by nocturnal nasogastric feedings. Am J Dis Child 140:438–443PubMed Strife CF, Quinlan M, Mears K, Davey ML, Clardy C (1986) Improved growth of three uremic children by nocturnal nasogastric feedings. Am J Dis Child 140:438–443PubMed
20.
go back to reference Rees L, Azocar M, Borzych D, Watson AR, Buscher A, Edefonti A, Bilge I, Askenazi D, Leozappa G, Gonzales C, van Hoeck K, Secker D, Zurowska A, Ronnholm K, Bouts AH, Stewart H, Ariceta G, Ranchin B, Warady BA, Schaefer F, International Pediatric Peritoneal Dialysis Network (2011) Growth in very young children undergoing chronic peritoneal dialysis. J Am Soc Nephrol 22:2303–2312CrossRefPubMedCentralPubMed Rees L, Azocar M, Borzych D, Watson AR, Buscher A, Edefonti A, Bilge I, Askenazi D, Leozappa G, Gonzales C, van Hoeck K, Secker D, Zurowska A, Ronnholm K, Bouts AH, Stewart H, Ariceta G, Ranchin B, Warady BA, Schaefer F, International Pediatric Peritoneal Dialysis Network (2011) Growth in very young children undergoing chronic peritoneal dialysis. J Am Soc Nephrol 22:2303–2312CrossRefPubMedCentralPubMed
21.
go back to reference Group KW (2009) KDOQI clinical practice guideline for nutrition in children with CKD: 2008 update. Executive summary. Am J Kidney Dis 53:S11–S104 Group KW (2009) KDOQI clinical practice guideline for nutrition in children with CKD: 2008 update. Executive summary. Am J Kidney Dis 53:S11–S104
22.
go back to reference Hijazi R, Abitbol CL, Chandar J, Seeherunvong W, Freundlich M, Zilleruelo G (2009) Twenty-five years of infant dialysis: a single center experience. J Pediatr 155:111–117CrossRefPubMed Hijazi R, Abitbol CL, Chandar J, Seeherunvong W, Freundlich M, Zilleruelo G (2009) Twenty-five years of infant dialysis: a single center experience. J Pediatr 155:111–117CrossRefPubMed
23.
go back to reference Rees L, Brandt ML (2010) Tube feeding in children with chronic kidney disease: technical and practical issues. Pediatr Nephrol 25:699–704CrossRefPubMed Rees L, Brandt ML (2010) Tube feeding in children with chronic kidney disease: technical and practical issues. Pediatr Nephrol 25:699–704CrossRefPubMed
24.
go back to reference Fein PA, Madane SJ, Jorden A, Babu K, Mushnick R, Avram MM, Grosman I (2001) Outcome of percutaneous endoscopic gastrostomy feeding in patients on peritoneal dialysis. Adv Perit Dial 17:148–152PubMed Fein PA, Madane SJ, Jorden A, Babu K, Mushnick R, Avram MM, Grosman I (2001) Outcome of percutaneous endoscopic gastrostomy feeding in patients on peritoneal dialysis. Adv Perit Dial 17:148–152PubMed
25.
go back to reference Warady BA, Bashir M, Donaldson LA (2000) Fungal peritonitis in children receiving peritoneal dialysis: a report of the NAPRTCS. Kidney Int 58:384–389CrossRefPubMed Warady BA, Bashir M, Donaldson LA (2000) Fungal peritonitis in children receiving peritoneal dialysis: a report of the NAPRTCS. Kidney Int 58:384–389CrossRefPubMed
26.
go back to reference Warady BA, Feneberg R, Verrina E, Flynn JT, Muller-Wiefel DE, Besbas N, Zurowska A, Aksu N, Fischbach M, Sojo E, Donmez O, Sever L, Sirin A, Alexander SR, Schaefer F, IPPR (2007) Peritonitis in children who receive long-term peritoneal dialysis: a prospective evaluation of therapeutic guidelines. J Am Soc Nephrol 18:2172–2179CrossRefPubMed Warady BA, Feneberg R, Verrina E, Flynn JT, Muller-Wiefel DE, Besbas N, Zurowska A, Aksu N, Fischbach M, Sojo E, Donmez O, Sever L, Sirin A, Alexander SR, Schaefer F, IPPR (2007) Peritonitis in children who receive long-term peritoneal dialysis: a prospective evaluation of therapeutic guidelines. J Am Soc Nephrol 18:2172–2179CrossRefPubMed
Metadata
Title
Infectious outcomes following gastrostomy in children receiving peritoneal dialysis
Authors
Chanel Prestidge
Jane Ronaldson
William Wong
Maria Stack
Tonya Kara
Publication date
01-05-2015
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Nephrology / Issue 5/2015
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-014-2951-z

Other articles of this Issue 5/2015

Pediatric Nephrology 5/2015 Go to the issue