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Published in: International Orthopaedics 1/2018

01-01-2018 | Original Paper

Infection risk assessment in patients undergoing primary total knee arthroplasty

Authors: Lazaros A. Poultsides, Georgios K. Triantafyllopoulos, Vasileios I. Sakellariou, Stavros G. Memtsoudis, Thomas P. Sculco

Published in: International Orthopaedics | Issue 1/2018

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Abstract

Purpose

To determine the incidence and to identify potential risk factors for in-hospital and late infections, as well as for deep periprosthetic joint infection (PJI) following TKA.

Methods

We identified 17,959 patients treated with primary TKA between 2000 and 2009. We recorded patient demographics, comorbidities and in-hospital complications. The rates of in-hospital, late, and deep PJIs were determined. Different logistic regression models were built to identify risk factors for each of the above types of infection.

Results

The rates for in-hospital, post-discharge, and deep PJI were 0.65%, 0.41%, and 0.26%, respectively. Younger age, allogeneic blood transfusion, liver disease, and unilateral or staged bilateral TKA were risk factors for in-hospital infection. Renal and pulmonary disease, urinary tract infection, wound dehiscence, and prior in-hospital infection were risk factors for post-discharge infection. Male gender, history of in-hospital infection, prolonged length of stay, and pulmonary disease were identified as risk factors for deep PJI.

Conclusion

Despite low infection rates after primary TKA, there are patients at higher risk that would benefit by addressing modifiable risk factors for both in-hospital or post-discharge infections, including deep PJIs.
Literature
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go back to reference Newman ET, Watters TS, Lewis JS, Jennings JM, Wellman SS, Attarian DE, Grant SA, Green CL, Vail TP, Bolognesi MP (2014) Impact of perioperative allogeneic and autologous blood transfusion on acute wound infection following total knee and total hip arthroplasty. J Bone Joint Surg Am 96(4):279–284. https://doi.org/10.2106/JBJS.L.01041 CrossRefPubMed Newman ET, Watters TS, Lewis JS, Jennings JM, Wellman SS, Attarian DE, Grant SA, Green CL, Vail TP, Bolognesi MP (2014) Impact of perioperative allogeneic and autologous blood transfusion on acute wound infection following total knee and total hip arthroplasty. J Bone Joint Surg Am 96(4):279–284. https://​doi.​org/​10.​2106/​JBJS.​L.​01041 CrossRefPubMed
Metadata
Title
Infection risk assessment in patients undergoing primary total knee arthroplasty
Authors
Lazaros A. Poultsides
Georgios K. Triantafyllopoulos
Vasileios I. Sakellariou
Stavros G. Memtsoudis
Thomas P. Sculco
Publication date
01-01-2018
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 1/2018
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-017-3675-z

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