Skip to main content
Top
Published in: Chinese Medicine 1/2018

Open Access 01-12-2018 | Review

Indigenous medicinal plants of Pakistan used to treat skin diseases: a review

Authors: Alamgeer, Amber Sharif, Hira Asif, Waqas Younis, Humayun Riaz, Ishfaq Ali Bukhari, Asaad Mohamed Assiri

Published in: Chinese Medicine | Issue 1/2018

Login to get access

Abstract

Ethno-pharmacological relevance

Plants are providing reliable therapy since time immemorial. Pakistan has a great diversity in medicinal flora and people use these ethno-medicines to deal with many skin problems. This review explores the fundamental knowledge on various dermatological properties of medicinal plants of Pakistan and is aimed to provide a baseline for the discovery of new plants having activities against skin issues.

Material and method

A total of 244 published articles were studied using different research engines like PubMed, Google, Google-scholar and science direct.

Results

Review of literature revealed ethno-pharmacological use of 545 plant species, belonging to 118 families and 355 genera, to combat various skin ailments. Out of these, ten most commonly used plant species belonging to ten different families are documented in this review. It was also found out that ehno-medicines are prepared using various parts of the plants including leaves (28.32%), whole plant and roots 13.17% and 10.97% respectively, in the form of powder (23.5%) and paste (22.75%). A total of 13 endangered plant species and ten commercially important plants were recorded.

Conclusion

Medicinal plants of Pakistan have therapeutic effects against several skin problems; however most of medicinal plants are still not evaluated scientifically to support their ethno-pharmacological claim on skin. Dermatological pathogens are recommended to study. Further, the conservational programs should be established for endangered species.
Literature
1.
go back to reference Musharaf K. Ethnobotanical studies on plant resources of Sheikh Maltoon, District Mardan, Pakistan. J Med Plants Res. 2014;4(5):35–45. Musharaf K. Ethnobotanical studies on plant resources of Sheikh Maltoon, District Mardan, Pakistan. J Med Plants Res. 2014;4(5):35–45.
3.
go back to reference Ahmad M, Sultana S, Fazl-I-Hadi S, Ben Hadda T, Rashid S, Zafar M, Khan MA, Khan M, Yaseen G. An ethnobotanical study of medicinal plants in high mountainous region of Chail valley (District Swat–Pakistan). J Ethnibiol Ethnomed. 2014;10(1):36.CrossRef Ahmad M, Sultana S, Fazl-I-Hadi S, Ben Hadda T, Rashid S, Zafar M, Khan MA, Khan M, Yaseen G. An ethnobotanical study of medicinal plants in high mountainous region of Chail valley (District Swat–Pakistan). J Ethnibiol Ethnomed. 2014;10(1):36.CrossRef
4.
go back to reference Abbasi AM, Khan MA, Shah MH, Shah MM, Pervez A, Ahmad M. Ethnobotanical appraisal and cultural values of medicinally important wild edible vegetables of Lesser Himalayas-Pakistan. J Ethnibiol Ethnomed. 2013;9(1):66.CrossRef Abbasi AM, Khan MA, Shah MH, Shah MM, Pervez A, Ahmad M. Ethnobotanical appraisal and cultural values of medicinally important wild edible vegetables of Lesser Himalayas-Pakistan. J Ethnibiol Ethnomed. 2013;9(1):66.CrossRef
5.
go back to reference Bin Asad HHM, Murtaza G, Siraj S, Khan AS, Azhar S, Hussain SM, Ismail T, Hussain SM, Hussain I. Enlisting the scientifically unnoticed medicinal plants of Pakistan as a source of novel therapeutic agents showing anti-venom activity. Afr J Pharm Pharmacol. 2011;5(20):2292–305. Bin Asad HHM, Murtaza G, Siraj S, Khan AS, Azhar S, Hussain SM, Ismail T, Hussain SM, Hussain I. Enlisting the scientifically unnoticed medicinal plants of Pakistan as a source of novel therapeutic agents showing anti-venom activity. Afr J Pharm Pharmacol. 2011;5(20):2292–305.
6.
go back to reference Mussarat S, Abdel-Salam NM, Tariq A, Wazir SM, Ullah R, Adnan M. Use of ethnomedicinal plants by the people living around indus river. Evid Based Complement Alternat Med. 2014;2014:212634.PubMedCentralCrossRefPubMed Mussarat S, Abdel-Salam NM, Tariq A, Wazir SM, Ullah R, Adnan M. Use of ethnomedicinal plants by the people living around indus river. Evid Based Complement Alternat Med. 2014;2014:212634.PubMedCentralCrossRefPubMed
7.
go back to reference Khan AS, Hassan M, Ali S. Secondary metabolite studies of some selected plants of District Gilgit, Gilgit-Baltistan. Int J Pharmacog Phytochem Res. 2014;6(3):467–71. Khan AS, Hassan M, Ali S. Secondary metabolite studies of some selected plants of District Gilgit, Gilgit-Baltistan. Int J Pharmacog Phytochem Res. 2014;6(3):467–71.
8.
go back to reference Ahmad SS, Erum S, Khan MS, Nawaz M, Abdul W. Exploring the medicinal plants wealth: a traditional medico-botanical knowledge of local communities in Changa Manga Forest, Pakistan. Middle-East J. 2014;20(12):1772–9. Ahmad SS, Erum S, Khan MS, Nawaz M, Abdul W. Exploring the medicinal plants wealth: a traditional medico-botanical knowledge of local communities in Changa Manga Forest, Pakistan. Middle-East J. 2014;20(12):1772–9.
9.
go back to reference Manzoor M, Durrani J, Ayesha A. Uses of fruits, vegetables and herbs for the treatment of diabetes by the people of Quetta city. Sci Tech Dev. 2013;32(1):24–7. Manzoor M, Durrani J, Ayesha A. Uses of fruits, vegetables and herbs for the treatment of diabetes by the people of Quetta city. Sci Tech Dev. 2013;32(1):24–7.
10.
go back to reference Johnsy G, Sargunam SD, Kaviyarasan V. Indigenous knowledge of medicinal plants used for the treatment of skin diseases by the Kaani tribe of Kanyakumari District. Int Pharm Pharmaceut Sci. 2012;4(1):309–13. Johnsy G, Sargunam SD, Kaviyarasan V. Indigenous knowledge of medicinal plants used for the treatment of skin diseases by the Kaani tribe of Kanyakumari District. Int Pharm Pharmaceut Sci. 2012;4(1):309–13.
11.
go back to reference Ali H, Qaiser M. The ethnobotany of chitral valley. Pakistan with particular reference to medicinal plants. Pak J Bot. 2009;41(4):2009–41. Ali H, Qaiser M. The ethnobotany of chitral valley. Pakistan with particular reference to medicinal plants. Pak J Bot. 2009;41(4):2009–41.
12.
go back to reference Bibi T, Ahmad M, Tareen BR, Tareen MN, Jabeen R, Ur-Rehman S, Sultana S, Zafar M, Yaseen G. Ethnobotany of medicinal plants in district Mastung of Balochistan province-Pakistan. J Ethnopharmacol. 2014;157:79–89.CrossRefPubMed Bibi T, Ahmad M, Tareen BR, Tareen MN, Jabeen R, Ur-Rehman S, Sultana S, Zafar M, Yaseen G. Ethnobotany of medicinal plants in district Mastung of Balochistan province-Pakistan. J Ethnopharmacol. 2014;157:79–89.CrossRefPubMed
13.
go back to reference Arshad M, Ahmad M, Ahmed E, Saboor A, Abbas A, Sadiq S. An ethnobiological study in Kala Chitta hills of Pothwar region. Pakistan: multinomial logit specification. J Ethnobiol Ethnomed. 2014;10:13.PubMedCentralCrossRefPubMed Arshad M, Ahmad M, Ahmed E, Saboor A, Abbas A, Sadiq S. An ethnobiological study in Kala Chitta hills of Pothwar region. Pakistan: multinomial logit specification. J Ethnobiol Ethnomed. 2014;10:13.PubMedCentralCrossRefPubMed
14.
go back to reference Gilani SA, Khan AM, Qureshi RA, Sherwani SK, Rehman RU, Bukhari TZ. Advances in bioresearch ethno-medicinal treatment of common gastrointestinal disorders by indigenous people in Pakistan. Adv Biores. 2014;5(1):42–9. Gilani SA, Khan AM, Qureshi RA, Sherwani SK, Rehman RU, Bukhari TZ. Advances in bioresearch ethno-medicinal treatment of common gastrointestinal disorders by indigenous people in Pakistan. Adv Biores. 2014;5(1):42–9.
15.
go back to reference Shinwari KZ. Medicinal plants research in Pakistan. J Med Plants Res. 2010;4(3):161–76. Shinwari KZ. Medicinal plants research in Pakistan. J Med Plants Res. 2010;4(3):161–76.
16.
go back to reference Ahmed JM, Malik HZ, Khan S, Nasar S. Biological spectrum and ethnomedicinal uses of plants in Chellah district Muzaffarabad Azad Kashmir Pakistan. J Adv Bot Zool. 2014;1(4):1–5. Ahmed JM, Malik HZ, Khan S, Nasar S. Biological spectrum and ethnomedicinal uses of plants in Chellah district Muzaffarabad Azad Kashmir Pakistan. J Adv Bot Zool. 2014;1(4):1–5.
17.
go back to reference Shedayi AA, Gulshan B. Ethnomedicinal uses of plant resources in Gilgit-Baltistan of Pakistan. J Med Plants Res. 2012;6(29):4540–9. Shedayi AA, Gulshan B. Ethnomedicinal uses of plant resources in Gilgit-Baltistan of Pakistan. J Med Plants Res. 2012;6(29):4540–9.
18.
go back to reference Shaheen H, Nazir J, Firdous SS, Khalid A. Cosmetic ethnobotany practiced by tribal women of Kashmir Himalayas. Avicenna J Phytomed. 2014;4(4):239–50.PubMedCentralPubMed Shaheen H, Nazir J, Firdous SS, Khalid A. Cosmetic ethnobotany practiced by tribal women of Kashmir Himalayas. Avicenna J Phytomed. 2014;4(4):239–50.PubMedCentralPubMed
19.
go back to reference Hussain S, Malik F, Riaz H, Qayyum MA, Khalid N. Alternative and traditional medicines systems in Pakistan: history, regulation, trends, usefulness, challenges, prospects and limitations. New York: INTECH Open Access Publisher; 2012. Hussain S, Malik F, Riaz H, Qayyum MA, Khalid N. Alternative and traditional medicines systems in Pakistan: history, regulation, trends, usefulness, challenges, prospects and limitations. New York: INTECH Open Access Publisher; 2012.
20.
go back to reference Baloch PM, Marri MY, Qaisrani MA, Baloch A. Plants treasures, traditional knowledge and baloch society. Bi Ann Res J. 2013;28(1):1810–2174. Baloch PM, Marri MY, Qaisrani MA, Baloch A. Plants treasures, traditional knowledge and baloch society. Bi Ann Res J. 2013;28(1):1810–2174.
21.
go back to reference Bano A, Ahmad M, Zafar M, Sultana S, Rashid S, Khan MA. Ethnomedicinal knowledge of the most commonly used plants from Deosai Plateau, Western Himalayas, Gilgit Baltistan, Pakistan. J Ethnopharmacol. 2014;155:1046–52.CrossRefPubMed Bano A, Ahmad M, Zafar M, Sultana S, Rashid S, Khan MA. Ethnomedicinal knowledge of the most commonly used plants from Deosai Plateau, Western Himalayas, Gilgit Baltistan, Pakistan. J Ethnopharmacol. 2014;155:1046–52.CrossRefPubMed
22.
go back to reference Ahmad SK, Habib S. Indigenous knowledge of some medicinal plants of himalaya region, Dawarian Village, Neelum Valley, Azad Jammu and Kashmir, Pakistan. Univ J Plant Sci. 2014;2(2):40–7. Ahmad SK, Habib S. Indigenous knowledge of some medicinal plants of himalaya region, Dawarian Village, Neelum Valley, Azad Jammu and Kashmir, Pakistan. Univ J Plant Sci. 2014;2(2):40–7.
23.
go back to reference Hostettmann K, Marston A, Ndjoko Loset K, Wolfender JL. The potential of African plants as a source of drugs. Curr Org Chem. 2000;4(10):973–1010.CrossRef Hostettmann K, Marston A, Ndjoko Loset K, Wolfender JL. The potential of African plants as a source of drugs. Curr Org Chem. 2000;4(10):973–1010.CrossRef
25.
go back to reference De Wet H, Nkwanyana MN, van Vuuren SF. Medicinal plants used for the treatment of diarrhoea in northern Maputaland, KwaZulu-Natal Province, South Africa. J Ethnopharmacol. 2010;130(2):284–9.CrossRefPubMed De Wet H, Nkwanyana MN, van Vuuren SF. Medicinal plants used for the treatment of diarrhoea in northern Maputaland, KwaZulu-Natal Province, South Africa. J Ethnopharmacol. 2010;130(2):284–9.CrossRefPubMed
26.
go back to reference Njoroge GN, Bussmann RW. Ethnotherapeautic management of skin diseases among the Kikuyus of Central Kenya. J Ethnopharmacol. 2007;111(2):303–7.CrossRefPubMed Njoroge GN, Bussmann RW. Ethnotherapeautic management of skin diseases among the Kikuyus of Central Kenya. J Ethnopharmacol. 2007;111(2):303–7.CrossRefPubMed
27.
go back to reference Doğan A, Demirci S, Cağlayan AB, Kılıç E, Günal MY, Uslu U, Cumbul A, Sahin F. Sodium pentaborate pentahydrate and pluronic containing hydrogel increases cutaneous wound healing in vitro and in vivo. Biol Trace Elem Res. 2014;7(3):37–44. Doğan A, Demirci S, Cağlayan AB, Kılıç E, Günal MY, Uslu U, Cumbul A, Sahin F. Sodium pentaborate pentahydrate and pluronic containing hydrogel increases cutaneous wound healing in vitro and in vivo. Biol Trace Elem Res. 2014;7(3):37–44.
29.
go back to reference Tariq A, Musarat S, Adnan M. Review on ethno medicinal, phytochemical and pharmacological evidence of Himalayan anticancer plants. J Ethnopharmacol. 2015;164:96–119.CrossRefPubMed Tariq A, Musarat S, Adnan M. Review on ethno medicinal, phytochemical and pharmacological evidence of Himalayan anticancer plants. J Ethnopharmacol. 2015;164:96–119.CrossRefPubMed
30.
go back to reference Kumar K, Sharma YP, Manhas RK, Bhatia H. Ethnomedicinal plants of Shankaracharya Hill, Srinagar, J&K, India. J Ethnopharmacol. 2015;170:255–74.CrossRefPubMed Kumar K, Sharma YP, Manhas RK, Bhatia H. Ethnomedicinal plants of Shankaracharya Hill, Srinagar, J&K, India. J Ethnopharmacol. 2015;170:255–74.CrossRefPubMed
31.
go back to reference Barker MS, Kane NC, Matvienko M, Kozik A, Michelmore RW, Knapp SJ, Rieseberg LH. Multiple paleopolyploidizations during the evolution of the Compositae reveal parallel patterns of duplicate gene retention after millions of years. Mol Biol Evol. 2008;25(11):2445–55.PubMedCentralCrossRefPubMed Barker MS, Kane NC, Matvienko M, Kozik A, Michelmore RW, Knapp SJ, Rieseberg LH. Multiple paleopolyploidizations during the evolution of the Compositae reveal parallel patterns of duplicate gene retention after millions of years. Mol Biol Evol. 2008;25(11):2445–55.PubMedCentralCrossRefPubMed
32.
go back to reference Kumar S, Malhotra R, Kumar D. Euphorbia hirta: its chemistry, traditional and medicinal uses, and pharmacological activities. Pharmacogn Rev. 2010;4(7):58–61.PubMedCentralCrossRefPubMed Kumar S, Malhotra R, Kumar D. Euphorbia hirta: its chemistry, traditional and medicinal uses, and pharmacological activities. Pharmacogn Rev. 2010;4(7):58–61.PubMedCentralCrossRefPubMed
33.
go back to reference Saikia AP, Ryakala VK, Sharma P, Goswami P, Bora U. Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmetics. J Ethnopharmacol. 2006;106(2):149–57.CrossRefPubMed Saikia AP, Ryakala VK, Sharma P, Goswami P, Bora U. Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmetics. J Ethnopharmacol. 2006;106(2):149–57.CrossRefPubMed
34.
go back to reference Mabona U, Van Vuuren FS. Southern African medicinal plants used to treat skin diseases. S Afr J Bot. 2013;87:175–93.CrossRef Mabona U, Van Vuuren FS. Southern African medicinal plants used to treat skin diseases. S Afr J Bot. 2013;87:175–93.CrossRef
35.
go back to reference Khan SM, Page S, Ahmad H, Harper D. Identifying plant species and communities across environmental gradients in the Western Himalayas: method development and conservation use. Ecol Inf. 2013;14:99–103.CrossRef Khan SM, Page S, Ahmad H, Harper D. Identifying plant species and communities across environmental gradients in the Western Himalayas: method development and conservation use. Ecol Inf. 2013;14:99–103.CrossRef
36.
go back to reference Ahmad M, Qureshi R, Arshad M, Khan MA, Zafar M. Traditional herbal remedies used for the treatment of diabetes from district Attock (Pakistan). Pak J Bot. 2009;41(6):2777–82. Ahmad M, Qureshi R, Arshad M, Khan MA, Zafar M. Traditional herbal remedies used for the treatment of diabetes from district Attock (Pakistan). Pak J Bot. 2009;41(6):2777–82.
37.
go back to reference Bhat JA, Kumar M, Bussmann RW. Ecological status and traditional knowledge of medicinal plants in Kedarnath Wildlife Sanctuary of Garhwal Himalaya, India. J Ethnobiol Ethnomed. 2013;9:1.PubMedCentralCrossRefPubMed Bhat JA, Kumar M, Bussmann RW. Ecological status and traditional knowledge of medicinal plants in Kedarnath Wildlife Sanctuary of Garhwal Himalaya, India. J Ethnobiol Ethnomed. 2013;9:1.PubMedCentralCrossRefPubMed
38.
go back to reference Ghorbani A. Studies on pharmaceutical ethnobotany in the region of Turkmen Sahra, north of Iran:(part 1): general results. J Ethnopharmacol. 2005;102(1):58–68.CrossRefPubMed Ghorbani A. Studies on pharmaceutical ethnobotany in the region of Turkmen Sahra, north of Iran:(part 1): general results. J Ethnopharmacol. 2005;102(1):58–68.CrossRefPubMed
39.
go back to reference Ayyanar M, Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India. J Ethnopharmacol. 2011;134:851–64.CrossRefPubMed Ayyanar M, Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India. J Ethnopharmacol. 2011;134:851–64.CrossRefPubMed
40.
go back to reference Adnan M, Ullah I, Tariq A, Murad W, Azizullah A, Khan AL, Ali N. Ethnomedicine use in the war affected region of northwest Pakistan. J Ethnobiol Ethnomed. 2014;10:1–16.CrossRef Adnan M, Ullah I, Tariq A, Murad W, Azizullah A, Khan AL, Ali N. Ethnomedicine use in the war affected region of northwest Pakistan. J Ethnobiol Ethnomed. 2014;10:1–16.CrossRef
41.
go back to reference Farnsworth NR. The role of ethnopharmacology in drug development. In: Chadwick DJ, Marsh J, editors. Bioactive compounds from plants Ciba-Geigy Symposium No154 Bangkok 20–22February. Wiley: New York; 1990. p. 2–21. Farnsworth NR. The role of ethnopharmacology in drug development. In: Chadwick DJ, Marsh J, editors. Bioactive compounds from plants Ciba-Geigy Symposium No154 Bangkok 20–22February. Wiley: New York; 1990. p. 2–21.
42.
go back to reference Watt JM, Breyer-Brandwijk MG. The medicinal and poisonous plants of southern and eastern Africa. 2nd ed. London: Livingstone Edinburgh; 1962. p. 205–6. Watt JM, Breyer-Brandwijk MG. The medicinal and poisonous plants of southern and eastern Africa. 2nd ed. London: Livingstone Edinburgh; 1962. p. 205–6.
43.
go back to reference Hutchings A. Zulu medicinal plants: an inventory. Kwazulu: University of Kwazulu Natal Press; 1996. Hutchings A. Zulu medicinal plants: an inventory. Kwazulu: University of Kwazulu Natal Press; 1996.
44.
go back to reference Felhaber T. South African traditional healers’ primary health care handbook, Kagiso Publishers. South Africa: Cape Town; 1997. Felhaber T. South African traditional healers’ primary health care handbook, Kagiso Publishers. South Africa: Cape Town; 1997.
45.
go back to reference Williams VL, Balkwill K, Witkowski ET. Unraveling the commercial market for medicinal plants and plant parts on the Witwatersrand, South Africa. Econ Bot. 2000;54(3):310–27.CrossRef Williams VL, Balkwill K, Witkowski ET. Unraveling the commercial market for medicinal plants and plant parts on the Witwatersrand, South Africa. Econ Bot. 2000;54(3):310–27.CrossRef
46.
go back to reference Bhatt D, Joshi GC, Kumar R, Tewari LM. Phytosociological features and threat categorization of A heterophyllum Wall. ex. Royle and A. ferox Wall. ex. Ser. in Kumaun. J Ecol Nat Environ. 2014;6(3):111–8.CrossRef Bhatt D, Joshi GC, Kumar R, Tewari LM. Phytosociological features and threat categorization of A heterophyllum Wall. ex. Royle and A. ferox Wall. ex. Ser. in Kumaun. J Ecol Nat Environ. 2014;6(3):111–8.CrossRef
47.
go back to reference Ved DK, Kinhal GA, Ravikumar K, Prabhakaran V, Ghate U, Sankar RV, Indresha JH. Conservation assessment & management prioritisation for the medicinal plants of Jammu & Kashmir. Himachal Pradesh: Foundation for Revitalisation of Local Health Traditions; 2003. Ved DK, Kinhal GA, Ravikumar K, Prabhakaran V, Ghate U, Sankar RV, Indresha JH. Conservation assessment & management prioritisation for the medicinal plants of Jammu & Kashmir. Himachal Pradesh: Foundation for Revitalisation of Local Health Traditions; 2003.
48.
go back to reference Ved DK, Kinhal GA, Ravikumar K, Sankar RV, Haridasan K. Conservation Assessment and Management Prioritisation (CAMP) for wild medicinal plants of North-East India. Med Plant Conserv. 2005;11:40–4. Ved DK, Kinhal GA, Ravikumar K, Sankar RV, Haridasan K. Conservation Assessment and Management Prioritisation (CAMP) for wild medicinal plants of North-East India. Med Plant Conserv. 2005;11:40–4.
49.
go back to reference Belt J, Lengkeek A, VanderZant J. Cultivating a healthy enterprise: developing a sustainable medicinal plant chain in Uttaranchal-India. Amsterdam: KIT Publishers; 2003. p. 350. Belt J, Lengkeek A, VanderZant J. Cultivating a healthy enterprise: developing a sustainable medicinal plant chain in Uttaranchal-India. Amsterdam: KIT Publishers; 2003. p. 350.
50.
go back to reference Srivastava N, Sharma V, Kamal B, Jadon VS. Aconitum: need for sustainable exploitation (with special reference to Uttarakhand). Int J Green Pharm. 2010;4:220–8.CrossRef Srivastava N, Sharma V, Kamal B, Jadon VS. Aconitum: need for sustainable exploitation (with special reference to Uttarakhand). Int J Green Pharm. 2010;4:220–8.CrossRef
51.
go back to reference Soni V. Conservation of Commiphora wightii, an endangered medicinal shrub, through propagation and planting, and education awareness programs in the Aravali Hills of Rajasthan, India. Cons Eviron. 2010;7(2):27–31. Soni V. Conservation of Commiphora wightii, an endangered medicinal shrub, through propagation and planting, and education awareness programs in the Aravali Hills of Rajasthan, India. Cons Eviron. 2010;7(2):27–31.
52.
go back to reference Goraya GS, Jishtu V, Rawat GS, Ved DK. Wild medicinal plants of Himachal Pradesh: an assessment of their conservation status and management prioritisation. Shimla: Himachal Pradesh Forest Department; 2013. Goraya GS, Jishtu V, Rawat GS, Ved DK. Wild medicinal plants of Himachal Pradesh: an assessment of their conservation status and management prioritisation. Shimla: Himachal Pradesh Forest Department; 2013.
53.
go back to reference Singh SK, Rawat GS. Flora of Great Himalayan National Park: Himachal Pradesh; 2000. Singh SK, Rawat GS. Flora of Great Himalayan National Park: Himachal Pradesh; 2000.
54.
go back to reference Shinwari ZK, Watanabe T, Rehman M, Youshikawa T. A Pictorial Guide to medicinal plants of Pakistan. Kohat: Kohat University of Science and Technology; 2006. Shinwari ZK, Watanabe T, Rehman M, Youshikawa T. A Pictorial Guide to medicinal plants of Pakistan. Kohat: Kohat University of Science and Technology; 2006.
55.
go back to reference Cano HJ, Volpado G. Herbal mixtures in the traditional medicines of eastern Cuba. J Ethnopharmacol. 2004;90:293–316.CrossRefPubMed Cano HJ, Volpado G. Herbal mixtures in the traditional medicines of eastern Cuba. J Ethnopharmacol. 2004;90:293–316.CrossRefPubMed
56.
go back to reference Haq F, Ahmad H, Alam M. Traditional uses of medicinal plants of Nandiar Khuwarr catchment (District Battagram), Pakistan. J Med Plants Res. 2011;5(1):39–48. Haq F, Ahmad H, Alam M. Traditional uses of medicinal plants of Nandiar Khuwarr catchment (District Battagram), Pakistan. J Med Plants Res. 2011;5(1):39–48.
57.
go back to reference Arshad M, Nisar FM, Majeed A, Ismail S, Ahmad M. Ethno medicinal flora in District Sialkot, Punjab, Pakistan. Middle-East J Sci Res. 2011;9(2):209–14. Arshad M, Nisar FM, Majeed A, Ismail S, Ahmad M. Ethno medicinal flora in District Sialkot, Punjab, Pakistan. Middle-East J Sci Res. 2011;9(2):209–14.
58.
go back to reference Kamal M, Wazir SM, Hassan M, Subhan M, Khan SU, Muhammad M, Taj S. Ethnobotanically important plants of district Bannu, Pakistan. Pak J Plant Sci. 2009;15(2):87–93. Kamal M, Wazir SM, Hassan M, Subhan M, Khan SU, Muhammad M, Taj S. Ethnobotanically important plants of district Bannu, Pakistan. Pak J Plant Sci. 2009;15(2):87–93.
59.
go back to reference Qureshi RM, Maqsood M, Arshad M, Chaudhry AK. Ethnomedicinal uses of plants by the people of Kadhi areas of Khushab, Punjab, Pakistan. Pak J Bot. 2011;43(1):121–33. Qureshi RM, Maqsood M, Arshad M, Chaudhry AK. Ethnomedicinal uses of plants by the people of Kadhi areas of Khushab, Punjab, Pakistan. Pak J Bot. 2011;43(1):121–33.
60.
go back to reference Ishtiaq M, Mumtaz SA, Hussain T, Ghani A. Medicinal plant diversity in the flora of Leepa Valley, Muzaffarabad (AJK), Pakistan. Afr J Biotechnol. 2012;11(13):3087–98. Ishtiaq M, Mumtaz SA, Hussain T, Ghani A. Medicinal plant diversity in the flora of Leepa Valley, Muzaffarabad (AJK), Pakistan. Afr J Biotechnol. 2012;11(13):3087–98.
61.
go back to reference Imtiaz S, Abdullah S, Afzal S, Rehman G, Waheed M. Medicinal plants used by traditional healers of Punjab, Pakistan. Can J App Sci. 2013;3(4):496–515. Imtiaz S, Abdullah S, Afzal S, Rehman G, Waheed M. Medicinal plants used by traditional healers of Punjab, Pakistan. Can J App Sci. 2013;3(4):496–515.
62.
go back to reference Begum S, Abdeislam NM, Adnan M, Tariq A, Yasmin A, Hameed R. Ethnomedicines of highly utilized plants in the temperate himalayan region. Afr J Tradit Complement Altern Med. 2014;11(3):132–42.PubMedCentralCrossRefPubMed Begum S, Abdeislam NM, Adnan M, Tariq A, Yasmin A, Hameed R. Ethnomedicines of highly utilized plants in the temperate himalayan region. Afr J Tradit Complement Altern Med. 2014;11(3):132–42.PubMedCentralCrossRefPubMed
63.
go back to reference Mahmood A, Mahmood A, Mujtaba G, Mumtaz MS, Kayani WK, Khan MA. Indigenous medicinal knowledge of common plants from district Kotli Azad Jammu and Kashmir Pakistan. J Med Plant Res. 2012;6:4961–7.CrossRef Mahmood A, Mahmood A, Mujtaba G, Mumtaz MS, Kayani WK, Khan MA. Indigenous medicinal knowledge of common plants from district Kotli Azad Jammu and Kashmir Pakistan. J Med Plant Res. 2012;6:4961–7.CrossRef
64.
go back to reference Abbasi AM, Khan MA, Ahmed M, Zafar M. Herbal medicines used to cure various ailments by the inhabitants of Abbottabad district, North West Frontier Province, Pakistan. Indian J Trad Know. 2010;9(1):175–83. Abbasi AM, Khan MA, Ahmed M, Zafar M. Herbal medicines used to cure various ailments by the inhabitants of Abbottabad district, North West Frontier Province, Pakistan. Indian J Trad Know. 2010;9(1):175–83.
65.
go back to reference Sabeen M, Ahmad DSS. Exploring the folk medicinal flora of Abbotabad City, Pakistan. Ethnobotl Leaflets. 2009;13:810–33. Sabeen M, Ahmad DSS. Exploring the folk medicinal flora of Abbotabad City, Pakistan. Ethnobotl Leaflets. 2009;13:810–33.
66.
go back to reference Rauf F, Qureshi R, Shaheen H. Folk medicinal uses of indigenous plant species of Barroha, Bhara Kahu and Maanga in Islamabad, Pakistan. J Med Plant Res. 2012;6(11):2061–70. Rauf F, Qureshi R, Shaheen H. Folk medicinal uses of indigenous plant species of Barroha, Bhara Kahu and Maanga in Islamabad, Pakistan. J Med Plant Res. 2012;6(11):2061–70.
67.
go back to reference Hussain K, Nisar FM, Majeed A, Nawaz K, Bhatti HK. Ethnomedicinal survey for important plants of Jalalpur Jattan, District Gujrat, Punjab, Pakistan. Ethnobot Leaflets. 2010;14:807–25. Hussain K, Nisar FM, Majeed A, Nawaz K, Bhatti HK. Ethnomedicinal survey for important plants of Jalalpur Jattan, District Gujrat, Punjab, Pakistan. Ethnobot Leaflets. 2010;14:807–25.
68.
go back to reference Naz I, Ahmad M, Ul-Hassan T. Ethnobotanical investigation of medicinal flora used by indigenous People in District Attock, Pakistan. J Adv Bot Zool. 2014;1(4):1–7. Naz I, Ahmad M, Ul-Hassan T. Ethnobotanical investigation of medicinal flora used by indigenous People in District Attock, Pakistan. J Adv Bot Zool. 2014;1(4):1–7.
69.
go back to reference Ahmad M, Khan AM, Manzoor S, Zafar M, Sultana S. Check list of medicinal flora of Tehsil Isakhel, District Mianwali-Pakistan. Ethnobot Leaflets. 2006;10:41–8. Ahmad M, Khan AM, Manzoor S, Zafar M, Sultana S. Check list of medicinal flora of Tehsil Isakhel, District Mianwali-Pakistan. Ethnobot Leaflets. 2006;10:41–8.
70.
go back to reference Ghani A, Ali Z, Perveen S. Folk recipes and ethno botanical survey of medicinal plants Mianwali district (Pakistan). Int J Curr Pharm Res. 2012;4(2):61–3. Ghani A, Ali Z, Perveen S. Folk recipes and ethno botanical survey of medicinal plants Mianwali district (Pakistan). Int J Curr Pharm Res. 2012;4(2):61–3.
71.
go back to reference Panhwar QA, Abro H. Ethnobotanical studies of Mahal Kohistan (Khirthar national park). Pak J Bot. 2009;39(7):2301–15. Panhwar QA, Abro H. Ethnobotanical studies of Mahal Kohistan (Khirthar national park). Pak J Bot. 2009;39(7):2301–15.
72.
go back to reference Mahmood A, Mahmood A, Shaheen H, Qureshi RA, Sangi Y, Gilani SA. Ethno medicinal survey of plants from district Bhimber Azad Jammu and Kashmir, Pakistan. J Med Plant Res. 2011;5(11):2348–60. Mahmood A, Mahmood A, Shaheen H, Qureshi RA, Sangi Y, Gilani SA. Ethno medicinal survey of plants from district Bhimber Azad Jammu and Kashmir, Pakistan. J Med Plant Res. 2011;5(11):2348–60.
73.
go back to reference Jabeen A, Khan MA, Ahmad M, Zafar M, Ahmad F. Indigenous uses of economically important flora of Margallah hills national park, Islamabad, Pakistan. Afr J Biotechnol. 2009;8(5):763–84. Jabeen A, Khan MA, Ahmad M, Zafar M, Ahmad F. Indigenous uses of economically important flora of Margallah hills national park, Islamabad, Pakistan. Afr J Biotechnol. 2009;8(5):763–84.
74.
go back to reference Mahmood A, Mahmood A, Malik RN. Indigenous knowledge of medicinal plants from Leepa valley, Azad Jammu and Kashmir, Pakistan. J Ethnopharmacol. 2012;143(1):338–46.CrossRefPubMed Mahmood A, Mahmood A, Malik RN. Indigenous knowledge of medicinal plants from Leepa valley, Azad Jammu and Kashmir, Pakistan. J Ethnopharmacol. 2012;143(1):338–46.CrossRefPubMed
75.
go back to reference Nisar MF, Jaleel F, Haider SM, Toor Y, Ismail S, Arfan M, Azeem M. Exploration of ethno-medicinal plants and their ritual uses in Bahawalnagar, Pakistan. Middle-East J Sci Res. 2014;21(9):1466–71. Nisar MF, Jaleel F, Haider SM, Toor Y, Ismail S, Arfan M, Azeem M. Exploration of ethno-medicinal plants and their ritual uses in Bahawalnagar, Pakistan. Middle-East J Sci Res. 2014;21(9):1466–71.
76.
go back to reference Shedayi AA, Xu M, Gulraiz B. Traditional medicinal uses of plants in Gilgit-Baltistan, Pakistan. J Med Plants Res. 2014;8(30):992–1004.CrossRef Shedayi AA, Xu M, Gulraiz B. Traditional medicinal uses of plants in Gilgit-Baltistan, Pakistan. J Med Plants Res. 2014;8(30):992–1004.CrossRef
77.
go back to reference Khan N, Ahmed M, Ahmed A, Shaukat SS, Wahab M, Ajaib M, Siddiqui FM, Nasir M. Important medicinal plants of Chitral Gol National Park (CGNP) Pakistan. Pak J Bot. 2011;43(2):797–809. Khan N, Ahmed M, Ahmed A, Shaukat SS, Wahab M, Ajaib M, Siddiqui FM, Nasir M. Important medicinal plants of Chitral Gol National Park (CGNP) Pakistan. Pak J Bot. 2011;43(2):797–809.
78.
go back to reference Parvaiz M, Bhatti KH, Nawaz K, Hussain Z, Khan RMW, Hussain A. Ethno-botanical studies of medicinal plants of Dinga, District Gujrat, Punjab, Pakistan. World Appl Sci J. 2013;26(6):826–33. Parvaiz M, Bhatti KH, Nawaz K, Hussain Z, Khan RMW, Hussain A. Ethno-botanical studies of medicinal plants of Dinga, District Gujrat, Punjab, Pakistan. World Appl Sci J. 2013;26(6):826–33.
79.
go back to reference Husain SZ, Malik RN, Javaid M, Bibi S. Ethonobotanical properties and uses of medicinal plants of Morgah biodiversity park, Rawalpindi. Pak J Bot. 2008;40(5):1897–911. Husain SZ, Malik RN, Javaid M, Bibi S. Ethonobotanical properties and uses of medicinal plants of Morgah biodiversity park, Rawalpindi. Pak J Bot. 2008;40(5):1897–911.
80.
go back to reference Awan AA, Murtaza G. Ethnobotanical uses of plants of family Solanaceae muzaffarabad division Azad Jammu and Kashmir, Pakistan-13100. Int Pharm Sci Invention. 2013;2(7):5–11. Awan AA, Murtaza G. Ethnobotanical uses of plants of family Solanaceae muzaffarabad division Azad Jammu and Kashmir, Pakistan-13100. Int Pharm Sci Invention. 2013;2(7):5–11.
81.
go back to reference Shah A, Marwat KS, Gohar F, Khan A, Bhatti HK, Amin M, Ud-Din N, Ahmad M, Zafar M. Ethnobotanical study of medicinal plants of semi-tribal area of Makerwal & Gulla Khel (lying between Khyber Pakhtunkhwa and Punjab Provinces), Pakistan. Am J Plant Sci. 2013;4:98–116.CrossRef Shah A, Marwat KS, Gohar F, Khan A, Bhatti HK, Amin M, Ud-Din N, Ahmad M, Zafar M. Ethnobotanical study of medicinal plants of semi-tribal area of Makerwal & Gulla Khel (lying between Khyber Pakhtunkhwa and Punjab Provinces), Pakistan. Am J Plant Sci. 2013;4:98–116.CrossRef
82.
go back to reference Jan G, Khan MA, Gul F. Ethnomedicinal plants used against diarrhea and dysentery in Dir Kohistan valley (NWFP), Pakistan. Ethnobot Leaflets. 2008;12:620–37. Jan G, Khan MA, Gul F. Ethnomedicinal plants used against diarrhea and dysentery in Dir Kohistan valley (NWFP), Pakistan. Ethnobot Leaflets. 2008;12:620–37.
83.
go back to reference Khan B, Abdukadir A, Qureshi R, Mustafa G. Medicinal uses of plants by the inhabitants of Khunjerab National Park, Gilgit, Pakistan. Pak J Bot. 2011;43(5):2301–10. Khan B, Abdukadir A, Qureshi R, Mustafa G. Medicinal uses of plants by the inhabitants of Khunjerab National Park, Gilgit, Pakistan. Pak J Bot. 2011;43(5):2301–10.
84.
go back to reference Afzal S, Afzal N, Awan RM, Khan ST, Gilani A, Khanum R, Tariq S. Ethno-botanical studies from Northern Pakistan. J Ayub Med Coll Abbottabad. 2009;21(1):52–7.PubMed Afzal S, Afzal N, Awan RM, Khan ST, Gilani A, Khanum R, Tariq S. Ethno-botanical studies from Northern Pakistan. J Ayub Med Coll Abbottabad. 2009;21(1):52–7.PubMed
85.
go back to reference Sarangzai MA, Ahmed A, Laghari KS. Traditional uses of some useful medicinal plants of Ziarat district Balochistan, Pakistan. FUUAST J Biol. 2013;3(1):101–7. Sarangzai MA, Ahmed A, Laghari KS. Traditional uses of some useful medicinal plants of Ziarat district Balochistan, Pakistan. FUUAST J Biol. 2013;3(1):101–7.
86.
go back to reference Patil RA, Makwana AB. Anti-hyperbilirubinemic and wound healing activity of aqueous extract of Calotropis procera leaves in Wistar rats. Ind J Pharmacol. 2015;47(4):398.CrossRef Patil RA, Makwana AB. Anti-hyperbilirubinemic and wound healing activity of aqueous extract of Calotropis procera leaves in Wistar rats. Ind J Pharmacol. 2015;47(4):398.CrossRef
87.
go back to reference Qaiser Joshi AL, Roham PH, Mhaske R, Jadhav M, Krishnadas K, Kharat A, Hardikar B, Kharat KR. Calotropis procera extract induces apoptosis and cell cycle arrest at G2/M phase in human skin melanoma (SK-MEL-2) cells. Nat Prod Res. 2015;29(23):2261–4.CrossRef Qaiser Joshi AL, Roham PH, Mhaske R, Jadhav M, Krishnadas K, Kharat A, Hardikar B, Kharat KR. Calotropis procera extract induces apoptosis and cell cycle arrest at G2/M phase in human skin melanoma (SK-MEL-2) cells. Nat Prod Res. 2015;29(23):2261–4.CrossRef
88.
go back to reference Aderounmu AO, Omonisi AE, Akingbasote JA, Makanjuola M, Bejide RA, Orafidiya LO, Adelusola KA. Wound-healing and potential anti-keloidal properties of the latex of Calotropis procera (Aiton) Asclepiadaceae in rabbits. Afr J Tradit Complement Altern Med. 2013;10(3):574–9.PubMedCentralPubMed Aderounmu AO, Omonisi AE, Akingbasote JA, Makanjuola M, Bejide RA, Orafidiya LO, Adelusola KA. Wound-healing and potential anti-keloidal properties of the latex of Calotropis procera (Aiton) Asclepiadaceae in rabbits. Afr J Tradit Complement Altern Med. 2013;10(3):574–9.PubMedCentralPubMed
89.
go back to reference Laitiff AA, Teoh SL, Das S. Wound healing in diabetes mellitus: traditional treatment modalities. Clin Ter. 2010;161(4):359–64.PubMed Laitiff AA, Teoh SL, Das S. Wound healing in diabetes mellitus: traditional treatment modalities. Clin Ter. 2010;161(4):359–64.PubMed
90.
go back to reference Rasik AM, Raghubir R, Gupta A, Shukla A, Dubey PM, Srivastava S, Jain KH, Kulshrestha KD. Healing potential of Calotropis procera on dermal wounds in Guinea pigs. J Ethnopharmacol. 1999;68(1–3):261–6.CrossRefPubMed Rasik AM, Raghubir R, Gupta A, Shukla A, Dubey PM, Srivastava S, Jain KH, Kulshrestha KD. Healing potential of Calotropis procera on dermal wounds in Guinea pigs. J Ethnopharmacol. 1999;68(1–3):261–6.CrossRefPubMed
91.
go back to reference Asif A, Kakub G, Mehmood S, Khunum R, Gulfraz M. Wound healing activity of root extracts of Berberis lyceum royle in rats. Phytother Res. 2007;21(6):589–91.CrossRefPubMed Asif A, Kakub G, Mehmood S, Khunum R, Gulfraz M. Wound healing activity of root extracts of Berberis lyceum royle in rats. Phytother Res. 2007;21(6):589–91.CrossRefPubMed
92.
go back to reference Pirzada AJ, Shaikh W, Usmanghani K, Mohiuddin E. Antifungal activity of Dodonaea viscosa Jacq extract on pathogenic fungi isolated from superficial skin infection. Pak J Pharm Sci. 2010;23(3):337–40.PubMed Pirzada AJ, Shaikh W, Usmanghani K, Mohiuddin E. Antifungal activity of Dodonaea viscosa Jacq extract on pathogenic fungi isolated from superficial skin infection. Pak J Pharm Sci. 2010;23(3):337–40.PubMed
93.
go back to reference Teshome K, Gebre-Mariam T, Asres K, Engidawork E. Toxicity studies on dermal application of plant extract of Dodonaea viscosa used in Ethiopian traditional medicine. Phytother Res. 2010;24(1):60–9.CrossRefPubMed Teshome K, Gebre-Mariam T, Asres K, Engidawork E. Toxicity studies on dermal application of plant extract of Dodonaea viscosa used in Ethiopian traditional medicine. Phytother Res. 2010;24(1):60–9.CrossRefPubMed
94.
go back to reference Patel M, Coogan MM, Teshome K, Gebre-Mariam T, Asres K, Engidawork E. Antifungal activity of the plant Dodonaea viscosa var. angustifolia on Candida albicans from HIV-infected patients. J Ethnopharmacol. 2008;118(1):173–6.CrossRefPubMed Patel M, Coogan MM, Teshome K, Gebre-Mariam T, Asres K, Engidawork E. Antifungal activity of the plant Dodonaea viscosa var. angustifolia on Candida albicans from HIV-infected patients. J Ethnopharmacol. 2008;118(1):173–6.CrossRefPubMed
95.
go back to reference Chakraborty A, Brantner A, Mukainaka T, Nobukuni Y, Kuchide M, Konoshima T, Tokuda H, Nishino H. Cancer chemopreventive activity of Achyranthes aspera leaves on Epstein–Barr virus activation and two-stage mouse skin carcinogenesis. Cancer Lett. 2002;177(1):1–5.CrossRefPubMed Chakraborty A, Brantner A, Mukainaka T, Nobukuni Y, Kuchide M, Konoshima T, Tokuda H, Nishino H. Cancer chemopreventive activity of Achyranthes aspera leaves on Epstein–Barr virus activation and two-stage mouse skin carcinogenesis. Cancer Lett. 2002;177(1):1–5.CrossRefPubMed
96.
go back to reference Taye B, Giday M, Animut A, Seid J. Antibacterial activities of selected medicinal plants in traditional treatment of human wounds in Ethiopia. Asian Pac J Trop Biomed. 2011;1(5):370–5.PubMedCentralCrossRefPubMed Taye B, Giday M, Animut A, Seid J. Antibacterial activities of selected medicinal plants in traditional treatment of human wounds in Ethiopia. Asian Pac J Trop Biomed. 2011;1(5):370–5.PubMedCentralCrossRefPubMed
97.
go back to reference Barua CC, Talukdar A, Begum SA, Pathak DC, Sarma DK, Borah RS, Gupta A. In vivo wound-healing efficacy and antioxidant activity of Achyranthes aspera in experimental burns. Pharm Biol. 2012;50(7):892–9.CrossRefPubMed Barua CC, Talukdar A, Begum SA, Pathak DC, Sarma DK, Borah RS, Gupta A. In vivo wound-healing efficacy and antioxidant activity of Achyranthes aspera in experimental burns. Pharm Biol. 2012;50(7):892–9.CrossRefPubMed
98.
go back to reference Fikru A, Makonnen E, Eguale T, Debella A, Abie Mekonnen G. Evaluation of in vivo wound healing activity of methanol extract of Achyranthes aspera L. J Ethnopharmacol. 2012;143(2):469–74.CrossRefPubMed Fikru A, Makonnen E, Eguale T, Debella A, Abie Mekonnen G. Evaluation of in vivo wound healing activity of methanol extract of Achyranthes aspera L. J Ethnopharmacol. 2012;143(2):469–74.CrossRefPubMed
99.
go back to reference Mukherjee H, Ojha D, Bag P, Chandel HS, Bhattacharyya S, Chatterjee TK, Mukherjee PK, Chakraborti S, Chattopadhyay D. Anti-herpes virus activities of Achyranthes aspera: an indian ethnomedicine, and its triterpene acid. Microbiol Res. 2013;168(4):238–44.CrossRefPubMed Mukherjee H, Ojha D, Bag P, Chandel HS, Bhattacharyya S, Chatterjee TK, Mukherjee PK, Chakraborti S, Chattopadhyay D. Anti-herpes virus activities of Achyranthes aspera: an indian ethnomedicine, and its triterpene acid. Microbiol Res. 2013;168(4):238–44.CrossRefPubMed
100.
go back to reference Gangopadhyay KS, Khan M, Pandit S, Chakrabarti S, Mondal TK, Biswas TK. Pharmacological evaluation and chemical standardization of an ayurvedic formulation for wound healing activity. Int J Low Extrem Wounds. 2014;13(1):41–9.CrossRefPubMed Gangopadhyay KS, Khan M, Pandit S, Chakrabarti S, Mondal TK, Biswas TK. Pharmacological evaluation and chemical standardization of an ayurvedic formulation for wound healing activity. Int J Low Extrem Wounds. 2014;13(1):41–9.CrossRefPubMed
101.
go back to reference Benson KF, Newman RA, Jensen GS. Antioxidant, anti-inflammatory, anti-apoptotic, and skin regenerative properties of an Aloe vera-based extract of Nerium oleander leaves (nae-8(®)). Clin Cosmet Investig Dermatol. 2015;8:239–48.PubMedCentralPubMed Benson KF, Newman RA, Jensen GS. Antioxidant, anti-inflammatory, anti-apoptotic, and skin regenerative properties of an Aloe vera-based extract of Nerium oleander leaves (nae-8(®)). Clin Cosmet Investig Dermatol. 2015;8:239–48.PubMedCentralPubMed
102.
go back to reference Ajose FO. Some Nigerian plants of dermatologic importance. Int J Dermatol. 2007;1:48–55.CrossRef Ajose FO. Some Nigerian plants of dermatologic importance. Int J Dermatol. 2007;1:48–55.CrossRef
103.
go back to reference Ali-Shtayeh MS, Al-Assali AA, Jamous RM. Antimicrobial activity of Palestinian medicinal plants against acne-inducing bacteria. Univ J Microbiol Res. 2013;7(21):2560–73. Ali-Shtayeh MS, Al-Assali AA, Jamous RM. Antimicrobial activity of Palestinian medicinal plants against acne-inducing bacteria. Univ J Microbiol Res. 2013;7(21):2560–73.
104.
go back to reference Nemudzivhadi V, Masoko P. In vitro assessment of cytotoxicity, antioxidant, and anti-inflammatory activities of ricinus communis (Euphorbiaceae) leaf extracts. Evid Based Complement Altern Med. 2014;2014:625961.CrossRef Nemudzivhadi V, Masoko P. In vitro assessment of cytotoxicity, antioxidant, and anti-inflammatory activities of ricinus communis (Euphorbiaceae) leaf extracts. Evid Based Complement Altern Med. 2014;2014:625961.CrossRef
105.
go back to reference Martínez GJ, Barboza GE. Natural pharmacopoeia used in traditional Toba medicine for the treatment of parasitosis and skin disorders (Central Chaco, Argentina). J Ethnopharmacol. 2010;132(1):86–100.CrossRefPubMed Martínez GJ, Barboza GE. Natural pharmacopoeia used in traditional Toba medicine for the treatment of parasitosis and skin disorders (Central Chaco, Argentina). J Ethnopharmacol. 2010;132(1):86–100.CrossRefPubMed
106.
go back to reference Lomash V, Parihar SK, Jain NK, Katiyar AK. Effect of Solanum nigrum and Ricinus communis extracts on histamine and carrageenan-induced inflammation in the chicken skin. Cell Mol Biol. 2010;9:56. Lomash V, Parihar SK, Jain NK, Katiyar AK. Effect of Solanum nigrum and Ricinus communis extracts on histamine and carrageenan-induced inflammation in the chicken skin. Cell Mol Biol. 2010;9:56.
107.
go back to reference Roh JS, Han JY, Kim JH, Hwang JK. Inhibitory effects of active compounds isolated from safflower (Carthamus tinctorius L.) seeds for melanogenesis. BiolPharm Bull. 2004;27(12):1976–8.CrossRef Roh JS, Han JY, Kim JH, Hwang JK. Inhibitory effects of active compounds isolated from safflower (Carthamus tinctorius L.) seeds for melanogenesis. BiolPharm Bull. 2004;27(12):1976–8.CrossRef
108.
go back to reference Chen YS, Lee SM, Lin CC, Liu CY, Wu MC, Shi WL. Kinetic study on the tyrosinase and melanin formation inhibitory activities of carthamus yellow isolated from Carthamus tinctorius L. J Biosci Bioeng. 2013;115(3):242–5.CrossRefPubMed Chen YS, Lee SM, Lin CC, Liu CY, Wu MC, Shi WL. Kinetic study on the tyrosinase and melanin formation inhibitory activities of carthamus yellow isolated from Carthamus tinctorius L. J Biosci Bioeng. 2013;115(3):242–5.CrossRefPubMed
109.
go back to reference Kong SZ, Shi XG, Feng XX, Li WJ, Liu WH, Chen ZW, Xie JH, Lai XP, Zhang SX, Zhang XJ, Su ZR. Inhibitory effect of hydroxysafflor yellow on mouse skin photoaging induced by ultraviolet irradiation. Rejuvenation Res. 2013;16(5):404–13.PubMedCentralCrossRefPubMed Kong SZ, Shi XG, Feng XX, Li WJ, Liu WH, Chen ZW, Xie JH, Lai XP, Zhang SX, Zhang XJ, Su ZR. Inhibitory effect of hydroxysafflor yellow on mouse skin photoaging induced by ultraviolet irradiation. Rejuvenation Res. 2013;16(5):404–13.PubMedCentralCrossRefPubMed
110.
go back to reference Joshi A, Sengar N, Prasad SK, Goel RK, Singh A, Hemalatha S. Wound-healing potential of the root extract of Albizzia lebbeck. Planta Med. 2013;79(9):737–43.CrossRefPubMed Joshi A, Sengar N, Prasad SK, Goel RK, Singh A, Hemalatha S. Wound-healing potential of the root extract of Albizzia lebbeck. Planta Med. 2013;79(9):737–43.CrossRefPubMed
111.
go back to reference Kováč I, Ďurkáč J, Hollý M, Jakubčová K, Peržeľová V, Mučaji P, Smetana K. Plantago lanceolata L. water extract induces transition of fibroblasts into myofibroblasts and increases tensile strength of healing skin wounds. J Pharm Pharmacol. 2015;67(1):117–25.CrossRefPubMed Kováč I, Ďurkáč J, Hollý M, Jakubčová K, Peržeľová V, Mučaji P, Smetana K. Plantago lanceolata L. water extract induces transition of fibroblasts into myofibroblasts and increases tensile strength of healing skin wounds. J Pharm Pharmacol. 2015;67(1):117–25.CrossRefPubMed
112.
go back to reference Sultana S, Khan AM, Ahmad M, Zafar M. Indigenous knowledge of folk herbal medicines by the women of District Chakwal, Pakistan. Ethnobot Leaflets. 2006;10:243–53. Sultana S, Khan AM, Ahmad M, Zafar M. Indigenous knowledge of folk herbal medicines by the women of District Chakwal, Pakistan. Ethnobot Leaflets. 2006;10:243–53.
113.
go back to reference Qureshi R, Bhatti GR, Memon RA. Ethnomedicinal uses of herbs from northern part of Nara desert, Pakistan. Pak J Bot. 2010;42(2):839–51. Qureshi R, Bhatti GR, Memon RA. Ethnomedicinal uses of herbs from northern part of Nara desert, Pakistan. Pak J Bot. 2010;42(2):839–51.
114.
go back to reference Ishtiaq M. Medicinal plant diversity in the flora of Leepa Valley, Muzaffarabad (AJK), Pakistan. Afr J Biotechnol. 2012;11(12):2087–98. Ishtiaq M. Medicinal plant diversity in the flora of Leepa Valley, Muzaffarabad (AJK), Pakistan. Afr J Biotechnol. 2012;11(12):2087–98.
115.
go back to reference Alam P, Ali M. Phytochemical investigation of Calotropis procera Ait roots. CSIR. 2009;48B(03):443–6. Alam P, Ali M. Phytochemical investigation of Calotropis procera Ait roots. CSIR. 2009;48B(03):443–6.
116.
go back to reference Sabir S, Tahir K, Rashid N, Naz S, Masood B, Shah MA, Sualeh M. Phytochemical and antioxidant studies of Berberis lycium. Pak J Pharm Sci. 2013;26(6):1165–72.PubMed Sabir S, Tahir K, Rashid N, Naz S, Masood B, Shah MA, Sualeh M. Phytochemical and antioxidant studies of Berberis lycium. Pak J Pharm Sci. 2013;26(6):1165–72.PubMed
117.
go back to reference Rani MS, Pippalla RS, Mohan K. Dodonaea viscosa Linn.—an overview. Asian J Pharm Res Health Care. 2009;1(1):97–112. Rani MS, Pippalla RS, Mohan K. Dodonaea viscosa Linn.—an overview. Asian J Pharm Res Health Care. 2009;1(1):97–112.
118.
go back to reference Srivastav S, Singh P, Mishra G, Jha KK, Khosa RL. Achyranthes aspera—n important medicinal plant: a review. J Nat Prod Plant Resour. 2011;1(1):1–14. Srivastav S, Singh P, Mishra G, Jha KK, Khosa RL. Achyranthes aspera—n important medicinal plant: a review. J Nat Prod Plant Resour. 2011;1(1):1–14.
119.
go back to reference Derwich E, Benziane Z, Boukir A. Antibacterial activity and chemical composition of the essential oil from flowers of Nerium oleander. Electronic J Environ Agric Food Chem. 2010;9:6. Derwich E, Benziane Z, Boukir A. Antibacterial activity and chemical composition of the essential oil from flowers of Nerium oleander. Electronic J Environ Agric Food Chem. 2010;9:6.
120.
go back to reference Jena J, Gupta AK. Ricinus communis Linn: a phytopharmacological review. Int J Pharm Pharm Sci. 2012;4(4):25–9. Jena J, Gupta AK. Ricinus communis Linn: a phytopharmacological review. Int J Pharm Pharm Sci. 2012;4(4):25–9.
121.
go back to reference Zhou YZ, Chen H, Qiao L, Hao DF, Hua HM, Pei YH. Chemical constituents from Carthamus tinctorius L. Chinese J Med Chem. 2007;17(6):380. Zhou YZ, Chen H, Qiao L, Hao DF, Hua HM, Pei YH. Chemical constituents from Carthamus tinctorius L. Chinese J Med Chem. 2007;17(6):380.
122.
go back to reference Zhao Y, Liu F, Lou HX. Studies on the chemical constituents of Solanum nigrum. J Chin Med Mater. 2010;33(4):555–6. Zhao Y, Liu F, Lou HX. Studies on the chemical constituents of Solanum nigrum. J Chin Med Mater. 2010;33(4):555–6.
123.
go back to reference Kokila K, Priyadharshini SD, Sujatha V. Phytopharmacological properties of Albizia species: a review. Int J Pharm Pharm Sci. 2013;5(3):70–3. Kokila K, Priyadharshini SD, Sujatha V. Phytopharmacological properties of Albizia species: a review. Int J Pharm Pharm Sci. 2013;5(3):70–3.
124.
go back to reference Tamura Y, Nishibe S. Changes in the concentrations of bioactive compounds in plantain leaves. J Agric Food Chem. 2002;50(9):2514–8.CrossRefPubMed Tamura Y, Nishibe S. Changes in the concentrations of bioactive compounds in plantain leaves. J Agric Food Chem. 2002;50(9):2514–8.CrossRefPubMed
125.
go back to reference Kavishankar GB, Lakshmidevi N, Murthy SM, Prakash HS, Niranjana SR. Diabetes and medicinal plants—a review. Int J Pharm Biomed Sci. 2011;2(3):65–80. Kavishankar GB, Lakshmidevi N, Murthy SM, Prakash HS, Niranjana SR. Diabetes and medicinal plants—a review. Int J Pharm Biomed Sci. 2011;2(3):65–80.
126.
go back to reference Ahmed N, Mahmood A, Mahmood A, Tahir SS, Bano A, Malik NR, Hassan S, Ishtiaq M. Relative importance of indigenous medicinal plants from Layyah district, Punjab Province, Pakistan. J Ethnopharmacol. 2014;155(1):509–23.CrossRefPubMed Ahmed N, Mahmood A, Mahmood A, Tahir SS, Bano A, Malik NR, Hassan S, Ishtiaq M. Relative importance of indigenous medicinal plants from Layyah district, Punjab Province, Pakistan. J Ethnopharmacol. 2014;155(1):509–23.CrossRefPubMed
127.
go back to reference Shinwari KZ, Gilani SS. Sustainable harvest of medicinal plants at Bulashbar Nullah, Astore (Northern Pakistan). J Ethnopharmacol. 2003;84:289–98.CrossRefPubMed Shinwari KZ, Gilani SS. Sustainable harvest of medicinal plants at Bulashbar Nullah, Astore (Northern Pakistan). J Ethnopharmacol. 2003;84:289–98.CrossRefPubMed
128.
go back to reference Hussain I, Bano A, Ullah F. Traditional drug therapies from various medicinal plants of Central Karakoram National Park. Pak J Bot. 2011;43:79–84. Hussain I, Bano A, Ullah F. Traditional drug therapies from various medicinal plants of Central Karakoram National Park. Pak J Bot. 2011;43:79–84.
129.
go back to reference Marwat KS, Khan AM, Ahmad M, Zafar M, Ur-Rehman F. Ethnophytomedicines for treatment of various diseases in DI, Khan District. J Agric. 2008;24(2):305–16. Marwat KS, Khan AM, Ahmad M, Zafar M, Ur-Rehman F. Ethnophytomedicines for treatment of various diseases in DI, Khan District. J Agric. 2008;24(2):305–16.
130.
go back to reference Hamayun M, Khan A, Afzal S, Khan MA. Study on traditional knowledge and utility of medicinal herbs of district Buner, NWFP, Pakistan. Indian J Trad Know. 2006;5(3):407–12. Hamayun M, Khan A, Afzal S, Khan MA. Study on traditional knowledge and utility of medicinal herbs of district Buner, NWFP, Pakistan. Indian J Trad Know. 2006;5(3):407–12.
131.
go back to reference Ghani A, Batool M. Folk recipes of some medicinal plants used by the inhabitants of soon valley khushab (Pakistan). Int J Curr Pharm Res. 2012;4(1):60–3. Ghani A, Batool M. Folk recipes of some medicinal plants used by the inhabitants of soon valley khushab (Pakistan). Int J Curr Pharm Res. 2012;4(1):60–3.
132.
go back to reference Marwat KS, Ur-Rehman F, Usman K, Khakwani AA, Ghulam S, Anwar N, Sadiq M, Khan JS. Medico-ethnobotanical studies of edible wild fruit plants species from the flora of north western Pakistan (D. I. Khan district). J Med Plants Res. 2011;5(16):3679–86. Marwat KS, Ur-Rehman F, Usman K, Khakwani AA, Ghulam S, Anwar N, Sadiq M, Khan JS. Medico-ethnobotanical studies of edible wild fruit plants species from the flora of north western Pakistan (D. I. Khan district). J Med Plants Res. 2011;5(16):3679–86.
133.
go back to reference Ajaib M, Ud-Din Khan Z. Ethnobotanical studies of useful trees of District Kotli, Azad Jammu and Kashmir. Biologia. 2014;60(1):63–71. Ajaib M, Ud-Din Khan Z. Ethnobotanical studies of useful trees of District Kotli, Azad Jammu and Kashmir. Biologia. 2014;60(1):63–71.
134.
go back to reference Khan K, Erum A, Ahmad B, Akram M, Anwar M, Junaid A, Saleem U. Ethnobotanical studies from northern areas of Pakistan. Pharmacologyonline. 2009;354:328–54. Khan K, Erum A, Ahmad B, Akram M, Anwar M, Junaid A, Saleem U. Ethnobotanical studies from northern areas of Pakistan. Pharmacologyonline. 2009;354:328–54.
135.
go back to reference Gulshan BA, Dasti AA, Hussain S, Atta IM, Amin-Ud-Din M. Indigenous uses of medicinal plants in rural areas of Dera ghazi khan, Punjab, Pakistan. Agric Biol Sci. 2012;7(9):750. Gulshan BA, Dasti AA, Hussain S, Atta IM, Amin-Ud-Din M. Indigenous uses of medicinal plants in rural areas of Dera ghazi khan, Punjab, Pakistan. Agric Biol Sci. 2012;7(9):750.
136.
go back to reference Hamayun M. Ethnobotanical studies of some useful shrubs and trees of District Buner, NWFP, Pakistan. Ethnobot Leaflets. 2003;1:12. Hamayun M. Ethnobotanical studies of some useful shrubs and trees of District Buner, NWFP, Pakistan. Ethnobot Leaflets. 2003;1:12.
137.
go back to reference Pavela R. History, presence and perspective of using plant extracts as commercial botanical insecticides and farm products for protection against insects—a review. Plant Prot Sci. 2016;52:229–41.CrossRef Pavela R. History, presence and perspective of using plant extracts as commercial botanical insecticides and farm products for protection against insects—a review. Plant Prot Sci. 2016;52:229–41.CrossRef
138.
go back to reference Jivad N, Bahmani M, Asadi-Samani M. A review of the most important medicinal plants effective on wound healing on ethnobotany evidence of Iran. Der Pharm Lett. 2016;8(2):353–7. Jivad N, Bahmani M, Asadi-Samani M. A review of the most important medicinal plants effective on wound healing on ethnobotany evidence of Iran. Der Pharm Lett. 2016;8(2):353–7.
Metadata
Title
Indigenous medicinal plants of Pakistan used to treat skin diseases: a review
Authors
Alamgeer
Amber Sharif
Hira Asif
Waqas Younis
Humayun Riaz
Ishfaq Ali Bukhari
Asaad Mohamed Assiri
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Chinese Medicine / Issue 1/2018
Electronic ISSN: 1749-8546
DOI
https://doi.org/10.1186/s13020-018-0210-0

Other articles of this Issue 1/2018

Chinese Medicine 1/2018 Go to the issue