Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Cancer Causes & Control
Published in: Cancer Causes & Control 2/2010

01-02-2010 | Original paper

Increasing trend of the incidence of esophageal squamous cell carcinoma, but not adenocarcinoma, in Taiwan

Authors: Ching-Liang Lu, Hui-Chu Lang, Jiing-Chyuan Luo, Chun-Chu Liu, Han-Chieh Lin, Full-Young Chang, Shou-Dong Lee

Published in: Cancer Causes & Control | Issue 2/2010

Login to get access

Abstract

Epidemiologic data on esophageal cancer in Asia are extremely limited. We examined temporal trends in the incidence of esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EA) in Taiwan. Patients with esophageal cancer were identified from the Taiwan Cancer Registry between 1979 and 2003. Age-standardized incidences of ESCC and EA were calculated based on the national census and world standard population. Trends in incidence rates were estimated by calculating the annual percentage change (APC). The age-standardized incidence of ESCC increased progressively (from 1979–1983 to 1999–2003: 2.63 to 4.37 per 100,000-year), with an APC higher in male (3.27%, P < 0.0001) than that in female (1.23%, P = 0.03). Though the crude incidence of EA progressively increased in both gender (male: 0.28–0.49 per 100,000-year; female 0.07–0.11 per 100,000-year), the age-standardized incidence of EA is similar along the study period with an APC of 0.72% (P = 0.20) in male and 1.59% (P = 0.30) in female. In Taiwan, the incidence of ESCC significantly increased from 1979 to 2003, whereas the incidence of EA remained unchanged. Although EA incidence has not recently increased, it could in the future.
Literature
1.
Devesa SS, Blot WJ, Fraumeni JF Jr (1998) Changing patterns in the incidence of esophageal and gastric carcinoma in the United States. Cancer 83:2049–2053CrossRefPubMed
2.
Newnham A, Quinn MJ, Babb P, Kang JY, Majeed A (2003) Trends in oesophageal and gastric cancer incidence, mortality and survival in England and Wales 1971–1998/1999. Aliment Pharmacol Ther 17:655–664CrossRefPubMed
3.
Brown LM, Devesa SS, Chow WH (2008) Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age. J Natl Cancer Inst 100:1184–1187CrossRefPubMed
4.
Whiteman DC, Sadeghi S, Pandeya N et al (2008) Combined effects of obesity, acid reflux and smoking on the risk of adenocarcinomas of the oesophagus. Gut 57:173–180CrossRefPubMed
5.
Lagergren J, Bergstrom R, Lindgren A, Nyren O (1999) Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 340:825–831CrossRefPubMed
6.
Trivers KF, Sabatino SA, Stewart SL (2008) Trends in esophageal cancer incidence by histology, United States, 1998–2003. Int J Cancer 123:1422–1428CrossRefPubMed
7.
Fernandes ML, Seow A, Chan YH, Ho KY (2006) Opposing trends in incidence of esophageal squamous cell carcinoma and adenocarcinoma in a multi-ethnic Asian country. Am J Gastroenterol 101:1430–1436CrossRefPubMed
8.
Yee YK, Cheung TK, Chan AO, Yuen MF, Wong BC (2007) Decreasing trend of esophageal adenocarcinoma in Hong Kong. Cancer Epidemiol Biomarkers Prev 16:2637–2640CrossRefPubMed
9.
Shibata A, Matsuda T, Ajiki W, Sobue T (2008) Trend in incidence of adenocarcinoma of the esophagus in Japan, 1993–2001. Jpn J Clin Oncol 38:464–468CrossRefPubMed
10.
Chang SS, Lu CL, Chao JY et al (2002) Unchanging trend of adenocarcinoma of the esophagus and gastric cardia in Taiwan: a 15-year experience in a single center. Dig Dis Sci 47:735–740CrossRefPubMed
11.
Fwu CW, Chien YC, Kirk GD et al (2009) Hepatitis B virus infection and hepatocellular carcinoma among parous Taiwanese women: nationwide cohort study. J Natl Cancer Inst 101:1019–1027CrossRefPubMed
12.
Chang MH, Chen CJ, Lai MS et al (1997) Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan childhood hepatoma study group. N Engl J Med 336:1855–1859CrossRefPubMed
13.
Chen MC, Feng IJ, Lu CH et al (2008) The incidence and risk of second primary cancers in patients with nasopharyngeal carcinoma: a population-based study in Taiwan over a 25-year period (1979–2003). Ann Oncol 19:1180–1186CrossRefPubMed
14.
Chen YY, You SL, Chen CA et al (2009) Effectiveness of national cervical cancer screening programme in Taiwan: 12-year experiences. Br J Cancer 101:174–177CrossRefPubMed
15.
Huang SY, Yao M, Tang JL et al (2007) Epidemiology of multiple myeloma in Taiwan: increasing incidence for the past 25 years and higher prevalence of extramedullary myeloma in patients younger than 55 years. Cancer 110:896–905CrossRefPubMed
16.
Parkin D, Whelan S, Ferlay J (2003) Cancer incidence in five continents Volume VIII. IARC Scientific Publications; IARC press, Lyon
17.
Walther C, Zilling T, Perfekt R, Moller T (2001) Increasing prevalence of adenocarcinoma of the oesophagus and gastro-oesophageal junction: a study of the Swedish population between 1970 and 1997. Eur J Surg 167:748–757CrossRefPubMed
18.
Vainio H, Wilbourn J (1992) Identification of carcinogens within the IARC monograph program. Scand J Work Environ Health 18(Suppl 1):64–73PubMed
19.
Hsu CC, Levy DT, Wen CP et al (2005) The effect of the market opening on trends in smoking rates in Taiwan. Health Policy 74:69–76CrossRefPubMed
20.
Freedman ND, Abnet CC, Leitzmann MF et al (2007) A prospective study of tobacco, alcohol, and the risk of esophageal and gastric cancer subtypes. Am J Epidemiol 165:1424–1433CrossRefPubMed
21.
Yang MJ (2002) The Chinese drinking problem: a review of the literature and its implication in a cross-cultural study. Kaohsiung J Med Sci 18:543–550PubMed
22.
Chou Q, Hong J, Chou P (1997) Prevalence of cigarettes smoking and betel nut chewing in Taiwan. Chin J Dent 16:28–36
23.
Yen L, Lu D, Lee L, Huang M, Teng H (1995) An investigation of healthy behaviors in Taiwanese adult: distribution, factor structure, and related factors. Chin J Public Health 14:358–368
24.
Ho PS, Ko YC, Yang YH, Shieh TY, Tsai CC (2002) The incidence of oropharyngeal cancer in Taiwan: an endemic betel quid chewing area. J Oral Pathol Med 31:213–219CrossRefPubMed
25.
Wu IC, Lu CY, Kuo FC et al (2006) Interaction between cigarette, alcohol and betel nut use on esophageal cancer risk in Taiwan. Eur J Clin Invest 36:236–241CrossRefPubMed
26.
Wu MT, Lee YC, Chen CJ (2001) Risk of betel chewing for oesophageal cancer in Taiwan. Br J Cancer 85:658–660CrossRefPubMed
27.
Wen CP, Tsai SP, Cheng TY et al (2005) Uncovering the relation between betel quid chewing and cigarette smoking in Taiwan. Tob Control 14(Suppl 1):i16–i22CrossRefPubMed
28.
Hwu HG, Yeh EK, Yeh YL, Chang LY (1988) Alcoholism by Chinese diagnostic interview schedule: a prevalence and validity study. Acta Psychiatr Scand 77:7–13CrossRefPubMed
29.
Wong BC, Kinoshita Y (2006) Systematic review on epidemiology of gastroesophageal reflux disease in Asia. Clin Gastroenterol Hepatol 4:398–407CrossRefPubMed
30.
Lu CL, Lang HC, Chang FY et al (2005) Social and medical impact, sleep quality and the pharmaceutical costs of heartburn in Taiwan. Aliment Pharmacol Ther 22:739–747CrossRefPubMed
31.
Lee YC, Wang HP, Chiu HM et al (2006) Comparative analysis between psychological and endoscopic profiles in patients with gastroesophageal reflux disease: a prospective study based on screening endoscopy. J Gastroenterol Hepatol 21:798–804CrossRefPubMed
32.
Chen PC, Wu CS, Chang-Chien CS, Liaw YF (1979) Comparison of Olympus GIF-P2 and GIF-K panendoscopy. Taiwan Yi Xue Hui Za Zhi 78:136–140PubMed
33.
Mold JW, Reed LE, Davis AB, Allen ML, Decktor DL, Robinson M (1991) Prevalence of gastroesophageal reflux in elderly patients in a primary care setting. Am J Gastroenterol 86:965–970PubMed
34.
Vaughan TL, Davis S, Kristal A, Thomas DB (1995) Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: adenocarcinoma versus squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 4:85–92PubMed
35.
Deurenberg P, Yap M, van Staveren WA (1998) Body mass index and percent body fat: a meta analysis among different ethnic groups. Int J Obes Relat Metab Disord 22:1164–1171CrossRefPubMed
36.
Rokkas T, Pistiolas D, Sechopoulos P, Robotis I, Margantinis G (2007) Relationship between Helicobacter pylori infection and esophageal neoplasia: a meta-analysis. Clin Gastroenterol Hepatol 5: 1413–1417, 1417 e1–1417 e12
37.
Teh BH, Lin JT, Pan WH et al (1994) Seroprevalence and associated risk factors of Helicobacter pylori infection in Taiwan. Anticancer Res 14:1389–1392PubMed
38.
Yang JC, Wang TH, Wang HJ, Kuo CH, Wang JT, Wang WC (1997) Genetic analysis of the cytotoxin-associated gene and the vacuolating toxin gene in Helicobacter pylori strains isolated from Taiwanese patients. Am J Gastroenterol 92:1316–1321PubMed
39.
Dooley CP, Cohen H, Fitzgibbons PL et al (1989) Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med 321:1562–1566PubMedCrossRef
40.
Crabtree JE, Taylor JD, Wyatt JI et al (1991) Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology. Lancet 338:332–335CrossRefPubMed
Metadata
Title
Increasing trend of the incidence of esophageal squamous cell carcinoma, but not adenocarcinoma, in Taiwan
Authors
Ching-Liang Lu
Hui-Chu Lang
Jiing-Chyuan Luo
Chun-Chu Liu
Han-Chieh Lin
Full-Young Chang
Shou-Dong Lee
Publication date
01-02-2010
Publisher
Springer Netherlands
Published in
Cancer Causes & Control / Issue 2/2010
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI
https://doi.org/10.1007/s10552-009-9458-0

Other articles of this Issue 2/2010

Cancer Causes & Control 2/2010 Go to the issue

Original paper

A comprehensive analysis of common genetic variation in MUC1, MUC5AC, MUC6 genes and risk of stomach cancer

Original paper

Objectively measured physical activity and sedentary time of breast cancer survivors, and associations with adiposity: findings from NHANES (2003–2006)

Original paper

Family history of cancer and malignant germ cell tumors in children: A report from the Children’s Oncology Group

Original paper

Citrus fruit and cancer risk in a network of case–control studies

Original paper

Mortality from malignant diseases—update of the Baltimore union poultry cohort

Original paper

Estimates of overdiagnosis of invasive breast cancer associated with screening mammography
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
Image Credits