Skip to main content
Top
Published in: Intensive Care Medicine 7/2012

01-07-2012 | Original

Increased nonbeneficial care in patients spending their birthday in the ICU

Authors: Elie Azoulay, Maité Garrouste, Dany Goldgran-Toledano, Christophe Adrie, Adeline Max, Aurélien Vesin, Adrien Francais, Jean-Ralph Zahar, Yves Cohen, Bernard Allaouchiche, Benoît Schlemmer, Jean-François Timsit

Published in: Intensive Care Medicine | Issue 7/2012

Login to get access

Abstract

Objective

End-of-life decisions are based on objective and subjective criteria. Previous studies identified substantial subjective biases during end-of-life decision-making. We evaluated whether in-ICU patient’s birthday influenced management decisions.

Design

We used a case–control design in which patients spending their birthday in the ICU (cases) were matched to controls on center, gender, age, severity, type of admission, and length of ICU stay before birthday.

Setting

12 ICUs in French hospitals.

Patients

The cases and controls were patients with ICU admissions >48 h over a 10-year period.

Interventions

None.

Measurements and main results

Compared with the 1,042 controls, the 223 cases were more often trauma patients and received a larger number and longer durations of life-sustaining interventions. This increased intensity of life support occurred after, but not before, the birthday. The cases had longer ICU stay lengths. ICU and hospital mortality were not different between the two groups. End-of-life decisions were made in 22% and 24% of cases and controls, respectively. However, these decisions were made later in the cases than in the controls (18 [5–33] versus 9 [3–19] days).

Conclusions

Our finding that patients who spent their birthday in the ICU received a higher intensity of life-sustaining care and had longer ICU stays but did not have significantly different mortality rates compared with the controls suggests the use of nonbeneficial interventions. Staff members caring for patients whose birthdays fall during the ICU stay should be aware that this feature can bias end-of-life decisions, leading to an inappropriate level of care.
Appendix
Available only for authorised users
Literature
1.
go back to reference Pochard F, Azoulay E, Chevret S, Vinsonneau C, Grassin M, Lemaire F, Herve C, Schlemmer B, Zittoun R, Dhainaut JF (2001) French intensivists do not apply American recommendations regarding decisions to forgo life-sustaining therapy. Crit Care Med 29:1887–1892PubMedCrossRef Pochard F, Azoulay E, Chevret S, Vinsonneau C, Grassin M, Lemaire F, Herve C, Schlemmer B, Zittoun R, Dhainaut JF (2001) French intensivists do not apply American recommendations regarding decisions to forgo life-sustaining therapy. Crit Care Med 29:1887–1892PubMedCrossRef
2.
go back to reference Prendergast TJ, Claessens MT, Luce JM (1998) A national survey of end-of-life care for critically ill patients. Am J Respir Crit Care Med 158:1163–1167PubMed Prendergast TJ, Claessens MT, Luce JM (1998) A national survey of end-of-life care for critically ill patients. Am J Respir Crit Care Med 158:1163–1167PubMed
3.
go back to reference Smedira NG, Evans BH, Grais LS, Cohen NH, Lo B, Cooke M, Schecter WP, Fink C, Epstein-Jaffe E, May C et al (1990) Withholding and withdrawal of life support from the critically ill. N Engl J Med 322:309–315PubMedCrossRef Smedira NG, Evans BH, Grais LS, Cohen NH, Lo B, Cooke M, Schecter WP, Fink C, Epstein-Jaffe E, May C et al (1990) Withholding and withdrawal of life support from the critically ill. N Engl J Med 322:309–315PubMedCrossRef
4.
go back to reference Sprung CL, Cohen SL, Sjokvist P, Baras M, Bulow HH, Hovilehto S, Ledoux D, Lippert A, Maia P, Phelan D, Schobersberger W, Wennberg E, Woodcock T (2003) End-of-life practices in European intensive care units: the Ethicus Study. JAMA 290:790–797PubMedCrossRef Sprung CL, Cohen SL, Sjokvist P, Baras M, Bulow HH, Hovilehto S, Ledoux D, Lippert A, Maia P, Phelan D, Schobersberger W, Wennberg E, Woodcock T (2003) End-of-life practices in European intensive care units: the Ethicus Study. JAMA 290:790–797PubMedCrossRef
5.
go back to reference Esteban A, Gordo F, Solsona JF, Alia I, Caballero J, Bouza C, Alcala-Zamora J, Cook DJ, Sanchez JM, Abizanda R, Miro G, Fernandez Del Cabo MJ, de Miguel E, Santos JA, Balerdi B (2001) Withdrawing and withholding life support in the intensive care unit: a Spanish prospective multi-centre observational study. Intensive Care Med 27:1744–1749PubMedCrossRef Esteban A, Gordo F, Solsona JF, Alia I, Caballero J, Bouza C, Alcala-Zamora J, Cook DJ, Sanchez JM, Abizanda R, Miro G, Fernandez Del Cabo MJ, de Miguel E, Santos JA, Balerdi B (2001) Withdrawing and withholding life support in the intensive care unit: a Spanish prospective multi-centre observational study. Intensive Care Med 27:1744–1749PubMedCrossRef
6.
go back to reference Azoulay E, Adrie C, De Lassence A, Pochard F, Moreau D, Thiery G, Cheval C, Moine P, Garrouste-Orgeas M, Alberti C, Cohen Y, Timsit JF (2003) Determinants of postintensive care unit mortality: a prospective multicenter study. Crit Care Med 31:428–432PubMedCrossRef Azoulay E, Adrie C, De Lassence A, Pochard F, Moreau D, Thiery G, Cheval C, Moine P, Garrouste-Orgeas M, Alberti C, Cohen Y, Timsit JF (2003) Determinants of postintensive care unit mortality: a prospective multicenter study. Crit Care Med 31:428–432PubMedCrossRef
7.
go back to reference Azoulay E, Metnitz B, Sprung CL, Timsit JF, Lemaire F, Bauer P, Schlemmer B, Moreno R, Metnitz P (2009) End-of-life practices in 282 intensive care units: data from the SAPS 3 database. Intensive Care Med 35:623–630PubMedCrossRef Azoulay E, Metnitz B, Sprung CL, Timsit JF, Lemaire F, Bauer P, Schlemmer B, Moreno R, Metnitz P (2009) End-of-life practices in 282 intensive care units: data from the SAPS 3 database. Intensive Care Med 35:623–630PubMedCrossRef
8.
go back to reference Azoulay E, Pochard F, Garrouste-Orgeas M, Moreau D, Montesino L, Adrie C, De Lassence A, Cohen Y, Timsit JF (2003) Decisions to forgo life-sustaining therapy in ICU patients independently predict hospital death. Intensive Care Med 29:1895–1901PubMedCrossRef Azoulay E, Pochard F, Garrouste-Orgeas M, Moreau D, Montesino L, Adrie C, De Lassence A, Cohen Y, Timsit JF (2003) Decisions to forgo life-sustaining therapy in ICU patients independently predict hospital death. Intensive Care Med 29:1895–1901PubMedCrossRef
9.
go back to reference Cook D, Rocker G, Marshall J, Sjokvist P, Dodek P, Griffith L, Freitag A, Varon J, Bradley C, Levy M, Finfer S, Hamielec C, McMullin J, Weaver B, Walter S, Guyatt G (2003) Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit. N Engl J Med 349:1123–1132PubMedCrossRef Cook D, Rocker G, Marshall J, Sjokvist P, Dodek P, Griffith L, Freitag A, Varon J, Bradley C, Levy M, Finfer S, Hamielec C, McMullin J, Weaver B, Walter S, Guyatt G (2003) Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit. N Engl J Med 349:1123–1132PubMedCrossRef
10.
go back to reference Asch DA (1996) The role of critical care nurses in euthanasia and assisted suicide. N Engl J Med 334:1374–1379PubMedCrossRef Asch DA (1996) The role of critical care nurses in euthanasia and assisted suicide. N Engl J Med 334:1374–1379PubMedCrossRef
11.
go back to reference Christakis NA, Asch DA (1993) Biases in how physicians choose to withdraw life support. Lancet 342:642–646PubMedCrossRef Christakis NA, Asch DA (1993) Biases in how physicians choose to withdraw life support. Lancet 342:642–646PubMedCrossRef
12.
go back to reference Prendergast TJ, Luce JM (1997) Increasing incidence of withholding and withdrawal of life support from the critically ill. Am J Respir Crit Care Med 155:15–20PubMed Prendergast TJ, Luce JM (1997) Increasing incidence of withholding and withdrawal of life support from the critically ill. Am J Respir Crit Care Med 155:15–20PubMed
13.
go back to reference Prendergast TJ, Puntillo KA (2002) Withdrawal of life support: intensive caring at the end of life. JAMA 288:2732–2740PubMedCrossRef Prendergast TJ, Puntillo KA (2002) Withdrawal of life support: intensive caring at the end of life. JAMA 288:2732–2740PubMedCrossRef
14.
go back to reference Asai A, Fukuhara S, Lo B (1995) Attitudes of Japanese and Japanese-American physicians towards life-sustaining treatment. Lancet 346:356–359PubMedCrossRef Asai A, Fukuhara S, Lo B (1995) Attitudes of Japanese and Japanese-American physicians towards life-sustaining treatment. Lancet 346:356–359PubMedCrossRef
15.
go back to reference van der Maas PJ, van der Wal G, Haverkate I, de Graaff CL, Kester JG, Onwuteaka-Philipsen BD, van der Heide A, Bosma JM, Willems DL (1996) Euthanasia, physician-assisted suicide, and other medical practices involving the end of life in the Netherlands, 1990–1995. N Engl J Med 335:1699–1705PubMedCrossRef van der Maas PJ, van der Wal G, Haverkate I, de Graaff CL, Kester JG, Onwuteaka-Philipsen BD, van der Heide A, Bosma JM, Willems DL (1996) Euthanasia, physician-assisted suicide, and other medical practices involving the end of life in the Netherlands, 1990–1995. N Engl J Med 335:1699–1705PubMedCrossRef
16.
go back to reference Keenan SP, Busche KD, Chen LM, Esmail R, Inman KJ, Sibbald WJ (1998) Withdrawal and withholding of life support in the intensive care unit: a comparison of teaching and community hospitals. The Southwestern Ontario Critical Care Research Network. Crit Care Med 26:245–251PubMedCrossRef Keenan SP, Busche KD, Chen LM, Esmail R, Inman KJ, Sibbald WJ (1998) Withdrawal and withholding of life support in the intensive care unit: a comparison of teaching and community hospitals. The Southwestern Ontario Critical Care Research Network. Crit Care Med 26:245–251PubMedCrossRef
17.
18.
go back to reference Mebane EW, Oman RF, Kroonen LT, Goldstein MK (1999) The influence of physician race, age, and gender on physician attitudes toward advance care directives and preferences for end-of-life decision-making. J Am Geriatr Soc 47:579–591PubMed Mebane EW, Oman RF, Kroonen LT, Goldstein MK (1999) The influence of physician race, age, and gender on physician attitudes toward advance care directives and preferences for end-of-life decision-making. J Am Geriatr Soc 47:579–591PubMed
19.
go back to reference Kelly WF, Eliasson AH, Stocker DJ, Hnatiuk OW (2002) Do specialists differ on do-not-resuscitate decisions? Chest 121:957–963PubMedCrossRef Kelly WF, Eliasson AH, Stocker DJ, Hnatiuk OW (2002) Do specialists differ on do-not-resuscitate decisions? Chest 121:957–963PubMedCrossRef
20.
go back to reference Kollef MH (1996) Private attending physician status and the withdrawal of life-sustaining interventions in a medical intensive care unit population. Crit Care Med 24:968–975PubMedCrossRef Kollef MH (1996) Private attending physician status and the withdrawal of life-sustaining interventions in a medical intensive care unit population. Crit Care Med 24:968–975PubMedCrossRef
22.
go back to reference Cook DJ, Guyatt GH, Jaeschke R, Reeve J, Spanier A, King D, Molloy DW, Willan A, Streiner DL (1995) Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill. Canadian Critical Care Trials Group. JAMA 273:703–708PubMedCrossRef Cook DJ, Guyatt GH, Jaeschke R, Reeve J, Spanier A, King D, Molloy DW, Willan A, Streiner DL (1995) Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill. Canadian Critical Care Trials Group. JAMA 273:703–708PubMedCrossRef
23.
go back to reference Luce JM, Lemaire F (2001) Two transatlantic viewpoints on an ethical quandary. Am J Respir Crit Care Med 163:818–821PubMed Luce JM, Lemaire F (2001) Two transatlantic viewpoints on an ethical quandary. Am J Respir Crit Care Med 163:818–821PubMed
24.
go back to reference Abel EL, Kruger ML (2006) Heaping in anniversary reaction studies: a cautionary note. Omega (Westport) 54:59–65 Abel EL, Kruger ML (2006) Heaping in anniversary reaction studies: a cautionary note. Omega (Westport) 54:59–65
25.
go back to reference Abel EL, Kruger ML (2009) Mortality salience of birthdays on day of death in the Major Leagues. Death Stud 33:175–184PubMedCrossRef Abel EL, Kruger ML (2009) Mortality salience of birthdays on day of death in the Major Leagues. Death Stud 33:175–184PubMedCrossRef
27.
go back to reference Timsit JF, Fosse JP, Troche G, De Lassence A, Alberti C, Garrouste-Orgeas M, Bornstain C, Adrie C, Cheval C, Chevret S (2002) Calibration and discrimination by daily Logistic Organ Dysfunction scoring comparatively with daily Sequential Organ Failure Assessment scoring for predicting hospital mortality in critically ill patients. Crit Care Med 30:2003–2013PubMedCrossRef Timsit JF, Fosse JP, Troche G, De Lassence A, Alberti C, Garrouste-Orgeas M, Bornstain C, Adrie C, Cheval C, Chevret S (2002) Calibration and discrimination by daily Logistic Organ Dysfunction scoring comparatively with daily Sequential Organ Failure Assessment scoring for predicting hospital mortality in critically ill patients. Crit Care Med 30:2003–2013PubMedCrossRef
28.
go back to reference Timsit JF, Fosse JP, Troche G, De Lassence A, Alberti C, Garrouste-Orgeas M, Azoulay E, Chevret S, Moine P, Cohen Y (2001) Accuracy of a composite score using daily SAPS II and LOD scores for predicting hospital mortality in ICU patients hospitalized for more than 72 h. Intensive Care Med 27:1012–1021PubMedCrossRef Timsit JF, Fosse JP, Troche G, De Lassence A, Alberti C, Garrouste-Orgeas M, Azoulay E, Chevret S, Moine P, Cohen Y (2001) Accuracy of a composite score using daily SAPS II and LOD scores for predicting hospital mortality in ICU patients hospitalized for more than 72 h. Intensive Care Med 27:1012–1021PubMedCrossRef
29.
go back to reference Zahar JR, Timsit JF, Garrouste-Orgeas M, Francais A, Vesin A, Descorps-Declere A, Dubois Y, Souweine B, Haouache H, Goldgran-Toledano D, Allaouchiche B, Azoulay E, Adrie C (2011) Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality. Crit Care Med 39:1886–1895PubMedCrossRef Zahar JR, Timsit JF, Garrouste-Orgeas M, Francais A, Vesin A, Descorps-Declere A, Dubois Y, Souweine B, Haouache H, Goldgran-Toledano D, Allaouchiche B, Azoulay E, Adrie C (2011) Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality. Crit Care Med 39:1886–1895PubMedCrossRef
30.
go back to reference Schneiderman LJ, Gilmer T, Teetzel HD, Dugan DO, Blustein J, Cranford R, Briggs KB, Komatsu GI, Goodman-Crews P, Cohn F, Young EW (2003) Effect of ethics consultations on nonbeneficial life-sustaining treatments in the intensive care setting: a randomized controlled trial. JAMA 290:1166–1172PubMedCrossRef Schneiderman LJ, Gilmer T, Teetzel HD, Dugan DO, Blustein J, Cranford R, Briggs KB, Komatsu GI, Goodman-Crews P, Cohn F, Young EW (2003) Effect of ethics consultations on nonbeneficial life-sustaining treatments in the intensive care setting: a randomized controlled trial. JAMA 290:1166–1172PubMedCrossRef
31.
go back to reference Gerstel E, Engelberg RA, Koepsell T, Curtis JR (2008) Duration of withdrawal of life support in the intensive care unit and association with family satisfaction. Am J Respir Crit Care Med 178:798–804PubMedCrossRef Gerstel E, Engelberg RA, Koepsell T, Curtis JR (2008) Duration of withdrawal of life support in the intensive care unit and association with family satisfaction. Am J Respir Crit Care Med 178:798–804PubMedCrossRef
32.
go back to reference Dodek PM, Heyland DK, Rocker GM, Cook DJ (2004) Translating family satisfaction data into quality improvement. Crit Care Med 32:1922–1927PubMedCrossRef Dodek PM, Heyland DK, Rocker GM, Cook DJ (2004) Translating family satisfaction data into quality improvement. Crit Care Med 32:1922–1927PubMedCrossRef
33.
go back to reference Phillips DP, King EW (1988) Death takes a holiday: mortality surrounding major social occasions. Lancet 2:728–732PubMedCrossRef Phillips DP, King EW (1988) Death takes a holiday: mortality surrounding major social occasions. Lancet 2:728–732PubMedCrossRef
34.
go back to reference Phillips DP, Smith DG (1990) Postponement of death until symbolically meaningful occasions. JAMA 263:1947–1951PubMedCrossRef Phillips DP, Smith DG (1990) Postponement of death until symbolically meaningful occasions. JAMA 263:1947–1951PubMedCrossRef
35.
go back to reference Young DC, Hade EM (2004) Holidays, birthdays, and postponement of cancer death. JAMA 292:3012–3016PubMedCrossRef Young DC, Hade EM (2004) Holidays, birthdays, and postponement of cancer death. JAMA 292:3012–3016PubMedCrossRef
36.
go back to reference Kesebir S, Oishi S (2010) A spontaneous self-reference effect in memory: why some birthdays are harder to remember than others. Psychol Sci 21:1525–1531PubMedCrossRef Kesebir S, Oishi S (2010) A spontaneous self-reference effect in memory: why some birthdays are harder to remember than others. Psychol Sci 21:1525–1531PubMedCrossRef
Metadata
Title
Increased nonbeneficial care in patients spending their birthday in the ICU
Authors
Elie Azoulay
Maité Garrouste
Dany Goldgran-Toledano
Christophe Adrie
Adeline Max
Aurélien Vesin
Adrien Francais
Jean-Ralph Zahar
Yves Cohen
Bernard Allaouchiche
Benoît Schlemmer
Jean-François Timsit
Publication date
01-07-2012
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 7/2012
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-012-2510-7

Other articles of this Issue 7/2012

Intensive Care Medicine 7/2012 Go to the issue