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European Archives of Oto-Rhino-Laryngology

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01-10-2013 | Otology

Increased levels of mean platelet volume: a possible relationship with idiopathic sudden hearing loss

Authors: Sahin Ulu, M. Sena Ulu, Ahmet Ahsen, Fatih Yucedag, Abdullah Aycicek, Sefa Celik

Published in: European Archives of Oto-Rhino-Laryngology | Issue 11/2013

Abstract

Mean platelet volume (MPV) is one of the platelet function indices which reflects the platelet production rate and functions. While vascular occlusion, acute or chronic syndromes and vasculitis are increasing the MPV levels, infections, autoimmune diseases, and inflammatory situations reduce it. The indicator for idiopathic sudden sensorineural hearing loss (ISHL) etiology remains a matter of debate because it is associated with many different disorders. We evaluated MPV levels in ISHL patients. Forty patients with ISHL and 40 healthy, age and sex matched subjects were enrolled to the study. Audiometer and laboratory results were recorded. Comparative multivariate analyses between indicator factors and hearing outcomes were conducted. MPV and platelet distribution width is significantly higher in ISHL. Platelet count is lower in the ISHL than control group (p < 0.001), (p < 0.001), (p = 0.003), respectively. Our findings indicate that, ISHL appears to be characterized by ischaemic or thrombotic events. Considering the increased MPV levels; MPV may be used to evaluate ISHL as an hepler indicator.

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Title: Increased levels of mean platelet volume: a possible relationship with idiopathic sudden hearing loss
Authors: Sahin Ulu
M. Sena Ulu
Ahmet Ahsen
Fatih Yucedag
Abdullah Aycicek
Sefa Celik
Publication date: 01-10-2013
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 11/2013
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-013-2348-9

At a glance: The STEP trials

Springer Medicine

Increased levels of mean platelet volume: a possible relationship with idiopathic sudden hearing loss

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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