Skip to main content
Top
Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2020

Open Access 01-12-2020 | Original research

Including oxygen supplement in the early warning score: a prediction study comparing TOKS, modified TOKS and NEWS in a cohort of emergency patients

Authors: Maj Juhl Skov, Jacob Dynesen, Marie K. Jessen, Janet Yde Liesanth, Julie Mackenhauer, Hans Kirkegaard

Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | Issue 1/2020

Login to get access

Abstract

Background

Early warning scores (EWS) are widely used in emergency departments and on general wards to detect critical illness and deterioration. TOKS (“Tidlig Opsporing af Kritisk Sygdom”) is an early warning score used in Central Denmark Region to monitor hospitalized patients.
The objective of this study is to investigate whether inclusion of supplement in the TOKS algorithm (modified TOKS; mTOKS), would improve the ability to predict 7-day mortality. Secondarily, we compare the discriminatory ability between TOKS, mTOKS and the National Early Warning Score (NEWS).

Methods

This is a prediction study including a cohort of adult patients who attended an emergency department in Central Denmark Region during a 3-month period in 2015. The discriminatory ability of TOKS, mTOKS and NEWS was evaluated by calculating the area under the receiver operating characteristics- curve (AUROC) with 7-day mortality as outcome. mTOKS was defined by adding 2 points for oxygen supplement to the normal TOKS score.

Results

18.853 patients were included. AUROC for TOKS: 0,78 (95%-CI: 0,76-0,81). AUROC for mTOKS: 0,81 (95 %-CI: 0,78-0,83). AUROC for NEWS: 0,83 (95%-CI: 0,80-0,85). The predictive ability of all three early warning scores are statistically significantly different from each other (p-value < 0,01).

Conclusion

The discriminatory ability of TOKS improved statistically by including oxygen supplement. All models showed moderate to good discriminatory ability.
Appendix
Available only for authorised users
Literature
1.
go back to reference Prytherch DR, Smith GB, Schmidt PE, Featherstone PI. ViEWS--Towards a national early warning score for detecting adult inpatient deterioration. Resuscitation. 2010;81:932–7.CrossRef Prytherch DR, Smith GB, Schmidt PE, Featherstone PI. ViEWS--Towards a national early warning score for detecting adult inpatient deterioration. Resuscitation. 2010;81:932–7.CrossRef
2.
go back to reference Smith GB, Prytherch DR, Meredith P, Schmidt PE, Featherstone PI. The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arrest, unanticipated intensive care unit admission, and death. Resuscitation. 2013;84:465–70.CrossRef Smith GB, Prytherch DR, Meredith P, Schmidt PE, Featherstone PI. The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arrest, unanticipated intensive care unit admission, and death. Resuscitation. 2013;84:465–70.CrossRef
3.
go back to reference Schein RM, Hazday N, Pena M, Ruben BH, Sprung CL. Clinical antecedents to in-hospital cardiopulmonary arrest. Chest. 1990;98:1388–92.CrossRef Schein RM, Hazday N, Pena M, Ruben BH, Sprung CL. Clinical antecedents to in-hospital cardiopulmonary arrest. Chest. 1990;98:1388–92.CrossRef
4.
go back to reference Lyons PG, Edelson DP, Churpek MM. Rapid response systems. Resuscitation. 2018;128:191–7.CrossRef Lyons PG, Edelson DP, Churpek MM. Rapid response systems. Resuscitation. 2018;128:191–7.CrossRef
5.
go back to reference Smith GB, Prytherch DR, Schmidt PE, Featherstone PI, Higgins B. A review, and performance evaluation, of single-parameter “track and trigger” systems. Resuscitation. 2008;79:11–21.CrossRef Smith GB, Prytherch DR, Schmidt PE, Featherstone PI, Higgins B. A review, and performance evaluation, of single-parameter “track and trigger” systems. Resuscitation. 2008;79:11–21.CrossRef
6.
go back to reference Christensen D, Jensen NM, Maaloe R, Rudolph SS, Belhage B, Perrild H. Nurse-administered early warning score system can be used for emergency department triage. Dan Med Bull. 2011;58:A4221.PubMed Christensen D, Jensen NM, Maaloe R, Rudolph SS, Belhage B, Perrild H. Nurse-administered early warning score system can be used for emergency department triage. Dan Med Bull. 2011;58:A4221.PubMed
7.
go back to reference Sestoft B, Rohde CV. The complexity of the implementation of an observation and tracking chart for critical illness. Ugeskr Laeger. 2011;173:2487–90.PubMed Sestoft B, Rohde CV. The complexity of the implementation of an observation and tracking chart for critical illness. Ugeskr Laeger. 2011;173:2487–90.PubMed
8.
go back to reference Petersen JA, Mackel R, Antonsen K, Rasmussen LS. Serious adverse events in a hospital using early warning score - what went wrong? Resuscitation. 2014;85:1699–703.CrossRef Petersen JA, Mackel R, Antonsen K, Rasmussen LS. Serious adverse events in a hospital using early warning score - what went wrong? Resuscitation. 2014;85:1699–703.CrossRef
9.
go back to reference Royal College of Physicians. National Early Warning Score (NEWS): Standardising the assessment of acute-illness severity in the NHS. Report of a working party. London: RCP; 2012. Royal College of Physicians. National Early Warning Score (NEWS): Standardising the assessment of acute-illness severity in the NHS. Report of a working party. London: RCP; 2012.
10.
go back to reference Smith GB, Prytherch DR, Schmidt PE, Featherstone PI, Kellett J, Deane B, et al. Should age be included as a component of track and trigger systems used to identify sick adult patients? Resuscitation. 2008;78:109–15.CrossRef Smith GB, Prytherch DR, Schmidt PE, Featherstone PI, Kellett J, Deane B, et al. Should age be included as a component of track and trigger systems used to identify sick adult patients? Resuscitation. 2008;78:109–15.CrossRef
11.
go back to reference Thygesen SK, Christiansen CF, Christensen S, Lash TL, Sorensen HT. The predictive value of ICD-10 diagnostic coding used to assess Charlson comorbidity index conditions in the population-based Danish National Registry of Patients. BMC Med Res Methodol. 2011;11:83.CrossRef Thygesen SK, Christiansen CF, Christensen S, Lash TL, Sorensen HT. The predictive value of ICD-10 diagnostic coding used to assess Charlson comorbidity index conditions in the population-based Danish National Registry of Patients. BMC Med Res Methodol. 2011;11:83.CrossRef
12.
go back to reference Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83.CrossRef Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83.CrossRef
13.
go back to reference Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982;143:29–36.CrossRef Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982;143:29–36.CrossRef
14.
go back to reference DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44:837–45.CrossRef DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44:837–45.CrossRef
15.
go back to reference O’Driscoll BR, Howard LS, Earis J, Mak V. British Thoracic Society Guideline for oxygen use in adults in healthcare and emergency settings. BMJ Open Respir Res. 2017;4:e000170.CrossRef O’Driscoll BR, Howard LS, Earis J, Mak V. British Thoracic Society Guideline for oxygen use in adults in healthcare and emergency settings. BMJ Open Respir Res. 2017;4:e000170.CrossRef
16.
go back to reference Smith GB, Prytherch DR, Schmidt PE, Featherstone PI. Review and performance evaluation of aggregate weighted ‘track and trigger’ systems. Resuscitation. 2008;77:170–9.CrossRef Smith GB, Prytherch DR, Schmidt PE, Featherstone PI. Review and performance evaluation of aggregate weighted ‘track and trigger’ systems. Resuscitation. 2008;77:170–9.CrossRef
17.
go back to reference Gao H, McDonnell A, Harrison DA, Moore T, Adam S, Daly K, et al. Systematic review and evaluation of physiological track and trigger warning systems for identifying at-risk patients on the ward. Intensive Care Med. 2007;33:667–79.CrossRef Gao H, McDonnell A, Harrison DA, Moore T, Adam S, Daly K, et al. Systematic review and evaluation of physiological track and trigger warning systems for identifying at-risk patients on the ward. Intensive Care Med. 2007;33:667–79.CrossRef
18.
go back to reference Petersen JA, Rasmussen LS, Rydahl-Hansen S. Barriers and facilitating factors related to use of early warning score among acute care nurses: a qualitative study. BMC Emerg Med. 2017;17:36.CrossRef Petersen JA, Rasmussen LS, Rydahl-Hansen S. Barriers and facilitating factors related to use of early warning score among acute care nurses: a qualitative study. BMC Emerg Med. 2017;17:36.CrossRef
19.
go back to reference Pedersen NE, Oestergaard D, Lippert A. End points for validating early warning scores in the context of rapid response systems: a Delphi consensus study. Acta Anaesthesiol Scand. 2016;60:616–22.CrossRef Pedersen NE, Oestergaard D, Lippert A. End points for validating early warning scores in the context of rapid response systems: a Delphi consensus study. Acta Anaesthesiol Scand. 2016;60:616–22.CrossRef
20.
go back to reference Dynesen J, Skov MJ, Mackenhauer J, Jessen MK, Liesanth JY, Ebdrup L, et al. The 7-day mortality associated with an early warning score varies between age groups in a cohort of adult Danish emergency department patients. Eur J Emerg Med. 2019;26(6):453–7.CrossRef Dynesen J, Skov MJ, Mackenhauer J, Jessen MK, Liesanth JY, Ebdrup L, et al. The 7-day mortality associated with an early warning score varies between age groups in a cohort of adult Danish emergency department patients. Eur J Emerg Med. 2019;26(6):453–7.CrossRef
Metadata
Title
Including oxygen supplement in the early warning score: a prediction study comparing TOKS, modified TOKS and NEWS in a cohort of emergency patients
Authors
Maj Juhl Skov
Jacob Dynesen
Marie K. Jessen
Janet Yde Liesanth
Julie Mackenhauer
Hans Kirkegaard
Publication date
01-12-2020
Publisher
BioMed Central
DOI
https://doi.org/10.1186/s13049-020-00720-1

Other articles of this Issue 1/2020

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2020 Go to the issue