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Oral and Maxillofacial Surgery

Published in:

01-12-2018 | Original Article

Incidental finding of subgemmal neurogenous plaque upon retrospective evaluation of oral lymphoepithelial cysts

Authors: Marcos Custódio, Priscila Lie Tobouti, Bruno Matuck, Suzana C. O. M. de Sousa

Published in: Oral and Maxillofacial Surgery | Issue 4/2018

Abstract

Purpose

We aimed to compare the histomorphological features of oral lymphoepithelial cysts (OLC) in different locations of the oral cavity and to verify the association between oral lymphoepithelial cysts and subgemmal neurogenous plaque (SNP) on biopsies from the lateral border of the tongue.

Methods

All cases diagnosed as OLC from the Oral Pathology Service at the School of Dentistry/University of São Paulo were retrieved. For all the cysts located in the tongue, their association to SNP was analyzed. Immunohistochemical staining against S100 was performed to confirm the diagnosis of SNP.

Results

Thirty-one cases were selected for morphological analysis and SNP was identified in 40% of cases, all of them positive for S100. In these cases, macroscopic analysis demonstrated two independent fragments. Microscopic analysis showed that cysts located in the floor of the mouth and ventral surface of the tongue showed less intense exocytosis, less formation of lymphoid follicles, and predominantly a moderate inflammatory infiltrate.

Conclusions

OLC have a similar histological pattern regardless the location within the oral cavity and. In some cases, the biopsy specimen may be accompanied by a SNP as an adjacent independent structure.

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Title: Incidental finding of subgemmal neurogenous plaque upon retrospective evaluation of oral lymphoepithelial cysts
Authors: Marcos Custódio
Priscila Lie Tobouti
Bruno Matuck
Suzana C. O. M. de Sousa
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: Oral and Maxillofacial Surgery / Issue 4/2018
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI: https://doi.org/10.1007/s10006-018-0726-6

At a glance: The STEP trials

Springer Medicine

Incidental finding of subgemmal neurogenous plaque upon retrospective evaluation of oral lymphoepithelial cysts

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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