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01-10-2010 | Interventional Neuroradiology

In vivo hemodynamic analysis of intracranial aneurysms obtained by magnetic resonance fluid dynamics (MRFD) based on time-resolved three-dimensional phase-contrast MRI

Authors: Haruo Isoda, Yasuhide Ohkura, Takashi Kosugi, Masaya Hirano, Hiroyasu Takeda, Hisaya Hiramatsu, Shuhei Yamashita, Yasuo Takehara, Marcus T. Alley, Roland Bammer, Norbert J. Pelc, Hiroki Namba, Harumi Sakahara

Published in: Neuroradiology | Issue 10/2010

Abstract

Introduction

Hemodynamics is thought to play a very important role in the initiation, growth, and rupture of intracranial aneurysms. The purpose of our study was to perform in vivo hemodynamic analysis of unruptured intracranial aneurysms of magnetic resonance fluid dynamics using time-resolved three-dimensional phase-contrast MRI (4D-Flow) at 1.5 T and to analyze relationships between hemodynamics and wall shear stress (WSS) and oscillatory shear index (OSI).

Methods

This study included nine subjects with 14 unruptured aneurysms. 4D-Flow was performed by a 1.5-T magnetic resonance scanner with a head coil. We calculated in vivo streamlines, WSS, and OSI of intracranial aneurysms based on 4D-Flow with our software. We evaluated the number of spiral flows in the aneurysms and compared the differences in WSS or OSI between the vessel and aneurysm and between whole aneurysm and the apex of the spiral flow.

Results

3D streamlines, WSS, and OSI distribution maps in arbitrary direction during the cardiac phase were obtained for all intracranial aneurysms. Twelve aneurysms had one spiral flow each, and two aneurysms had two spiral flows each. The WSS was lower and the OSI was higher in the aneurysm compared to the vessel. The apex of the spiral flow had a lower WSS and higher OSI relative to the whole aneurysm.

Conclusion

Each intracranial aneurysm in this study had at least one spiral flow. The WSS was lower and OSI was higher at the apex of the spiral flow than the whole aneurysmal wall.

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Title: In vivo hemodynamic analysis of intracranial aneurysms obtained by magnetic resonance fluid dynamics (MRFD) based on time-resolved three-dimensional phase-contrast MRI
Authors: Haruo Isoda
Yasuhide Ohkura
Takashi Kosugi
Masaya Hirano
Hiroyasu Takeda
Hisaya Hiramatsu
Shuhei Yamashita
Yasuo Takehara
Marcus T. Alley
Roland Bammer
Norbert J. Pelc
Hiroki Namba
Harumi Sakahara
Publication date: 01-10-2010
Publisher: Springer-Verlag
Published in: Neuroradiology / Issue 10/2010
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-009-0635-3

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Springer Medicine

In vivo hemodynamic analysis of intracranial aneurysms obtained by magnetic resonance fluid dynamics (MRFD) based on time-resolved three-dimensional phase-contrast MRI

Abstract

Introduction

Methods

Results

Conclusion

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Abstract

Introduction

Methods

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