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La radiologia medica

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01-11-2014 | Diagnostic Imaging in Oncology

In-depth analysis of local recurrence of giant cell tumour of bone with soft tissue extension after intralesional curettage

Authors: Liang Chen, Xiao-Yi Ding, Chengs-Sheng Wang, Ming-Jue Si, Lian-Jun Du, Wei-Bin Zhang, Yong Lu

Published in: La radiologia medica | Issue 11/2014

Abstract

Purpose

The aim of this study was to assess the local recurrence rate of giant cell tumour of bone (GCTB) with soft tissue extension, to identify characteristics of the soft tissue extension that can best indicate recurrence of GCTB after intralesional curettage.

Materials and methods

A total of 48 cases of GCTB with soft tissue extension after intralesional curettage were recruited. Patients were divided into two groups based on various objective features of soft tissue extension including size, number, margins, involvement of adjacent tissues, signal intensity, static enhancement and Jaffe grade. The local recurrence rate was compared using the Chi-square test and Chi-square value correction for continuity. Risk factors were assessed by multivariate logistic regression analysis.

Results

The local recurrence rate was significantly different according to soft tissue extension size, number and margins (p < 0.05). There was no significant difference in the groups of adjacent tissue involvement and Jaffe grade (p > 0.05). Size, number and margins of the soft tissue extension were independent risk factors of local recurrence of GCTB after intralesional curettage (p < 0.05).

Conclusions

The local recurrence rate of GCTB with soft tissue extension after intralesional curettage is higher if the soft tissue extension is large, multiple and lacking bone envelope integrity. For cases with the above-mentioned features, we suggest that the higher recurrence rate can be taken into full consideration when choosing appropriate surgical procedures.

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Title: In-depth analysis of local recurrence of giant cell tumour of bone with soft tissue extension after intralesional curettage
Authors: Liang Chen
Xiao-Yi Ding
Chengs-Sheng Wang
Ming-Jue Si
Lian-Jun Du
Wei-Bin Zhang
Yong Lu
Publication date: 01-11-2014
Publisher: Springer Milan
Published in: La radiologia medica / Issue 11/2014
Print ISSN: 0033-8362
Electronic ISSN: 1826-6983
DOI: https://doi.org/10.1007/s11547-014-0396-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

In-depth analysis of local recurrence of giant cell tumour of bone with soft tissue extension after intralesional curettage

Abstract

Purpose

Materials and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusions

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