Improvement in Psoriasis following Treatment with Gabapentin and Pregabalin

Excerpt

A 56-year-old White male with a history of psoriasis presented to a retail pharmacy stating that he had experienced improvement in his psoriasis since starting gabapentin and pregabalin for neuropathic pain. His medical history consisted of dyslipidemia, hypertension, panic attacks, neuropathic pain, and psoriasis. The patient had a family history of psoriasis, with both his father and brother having mild psoriasis covering <5% of their body. Based on the subjective data from the patient and limited objective documentation in his medical chart, the patient was classified as having mild-to-moderate psoriasis with guttate and erythrodermic lesions affecting at least 2–3% of his body surface. The main areas affected were his elbows, knees, back of the hands, face, legs, and buttocks. He had tried multiple topical treatments, including hydrocortisone and clobetasol, with only minimal benefits. The patient had never received systemic treatment for his psoriasis. …