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Published in: Surgical Endoscopy 9/2015

01-09-2015 | Technique

Improved procedures and comparative results for video-assisted thoracoscopic extended thymectomy for myasthenia gravis

Authors: Tomoyuki Nakagiri, Masayoshi Inoue, Yasushi Shintani, Soichiro Funaki, Tomohiro Kawamura, Masato Minami, Mitsunori Ohta, Yoshihisa Kadota, Hiroyuki Shiono, Meinoshin Okumura

Published in: Surgical Endoscopy | Issue 9/2015

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Abstract

Introduction

We previously introduced video-assisted thoracoscopic ET (VATS-ET) as a therapeutic option for MG with acceptable results. We have conducted further investigations to improve the procedure without deterioration of operative results, including myasthenia gravis (MG) remission rate and palliation rate. Here, we report the details of our current procedure, as well as surgical results and patient outcomes as compared with the original VATS-ET procedure.

Material and methods

From January 2002 to September 2013, we performed a VATS-ET procedure with an anterior chest wall lifting method for 77 patients who had MG with or without a thymoma. During that period, we investigated the appropriate indications and improved the procedure.

Results

Our current indication for this procedure is MG with the anti-acetylcholine receptor antibody or sero-negative type, or MG with a thymoma <5 cm in diameter without invasion to adjacent organs. With our procedure, the thymus and surrounding tissue are sufficiently resected using a bilateral thoracoscopic surgical method without neck incision. Remission and palliation rates were found to be equivalent to those obtained with the original VATS-ET procedure.

Conclusion

VATS-ET is suitable for select patients with MG with or without a thymoma. In addition, our current method has shown to be effective while also offering cosmetic advantages as compared with the original, neck incision needed, VATS-ET method.
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Metadata
Title
Improved procedures and comparative results for video-assisted thoracoscopic extended thymectomy for myasthenia gravis
Authors
Tomoyuki Nakagiri
Masayoshi Inoue
Yasushi Shintani
Soichiro Funaki
Tomohiro Kawamura
Masato Minami
Mitsunori Ohta
Yoshihisa Kadota
Hiroyuki Shiono
Meinoshin Okumura
Publication date
01-09-2015
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 9/2015
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-014-3964-1

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